Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q29RU0    431   RN128_BOVIN E3 ubiquitin-protein ligase RNF12...870.13     38.5     23     46GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
242Q9Y6U7    377   RN215_HUMAN RING finger protein 215 OS=Homo s...600.14     38.5     32     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
243Q4R6Y5    429   ZNRF4_MACFA Zinc/RING finger protein 4 OS=Mac...700.14     38.5     26     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
244O60117    268   YH73_SCHPO Uncharacterized RING finger protei...680.14     38.1     31     49GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
245Q9M0R5    345   ATL36_ARATH Putative RING-H2 finger protein A...520.15     38.1     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
246Q8TDB6    740   DTX3L_HUMAN E3 ubiquitin-protein ligase DTX3L...900.15     38.5     29     41GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.
247Q9ZT42    375   RHF2A_ARATH E3 ubiquitin-protein ligase RHF2A...550.15     38.1     33     44
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
248Q9FVV9    324   NAP5_ARATH Probable non-intrinsic ABC protein...1050.16     38.1     29     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
249Q1MTR5    556   YG66_SCHPO Uncharacterized RING finger membra...870.17     38.5     25     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
250Q9SZL4    145   ATL18_ARATH RING-H2 finger protein ATL18 OS=A...280.18     36.6     46     71GO:0031225; C:anchored to membrane; TAS:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
251Q66KG7    195   ZNRF1_XENLA E3 ubiquitin-protein ligase znrf1...530.18     37.4     34     51GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
252Q570X5    261   ATL58_ARATH RING-H2 finger protein ATL58 OS=A...680.18     37.7     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
253Q8GW38    369   ATL47_ARATH RING-H2 finger protein ATL47 OS=A...570.18     38.1     30     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
254P53804    2025   TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 O...330.19     38.5     39     55GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
255Q5SPX3    379   RN215_MOUSE RING finger protein 215 OS=Mus mu...570.19     38.1     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
256Q7KRW1    809   TRC8_DROME Protein TRC8 homolog OS=Drosophila...1030.2     38.1     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0007418; P:ventral midline development; IMP:UniProtKB.
257Q9SK92    381   ATL15_ARATH E3 ubiquitin-protein ligase ATL15...510.2     38.1     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033591; P:response to L-ascorbic acid; IEP:TAIR.::GO:0009416; P:response to light stimulus; IEP:TAIR.
258Q8LGA5    368   ATL31_ARATH E3 ubiquitin-protein ligase ATL31...530.2     37.7     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043562; P:cellular response to nitrogen levels; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IEP:UniProtKB.::GO:0010200; P:response to chitin; IEP:TAIR.
259Q8N7C7    305   RN148_HUMAN RING finger protein 148 OS=Homo s...610.2     37.7     30     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
260Q5Z5F2    251   ATL61_ORYSJ E3 ubiquitin-protein ligase Os06g...610.21     37.4     28     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
261Q61010    627   DTX1_MOUSE E3 ubiquitin-protein ligase DTX1 O...890.21     38.1     30     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IMP:MGI.::GO:0045581; P:negative regulation of T cell differentiation; IDA:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.
262Q93Z92    390   RING4_ARATH E3 ubiquitin-protein ligase At4g1...670.22     37.7     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
263F7EP40    195   ZNRF1_XENTR E3 ubiquitin-protein ligase znrf1...530.23     37     34     51GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
264Q67YI6    411   ATL65_ARATH RING-H2 finger protein ATL65 OS=A...700.23     37.7     27     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
265O82353    214   ATL67_ARATH RING-H2 finger protein ATL67 OS=A...550.23     37     31     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
266Q9UTL9    1375   YIV5_SCHPO Uncharacterized ATP-dependent heli...580.23     38.1     31     47GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:PomBase.
267P93823    381   ATL1_ARATH RING-H2 finger protein ATL1 OS=Ara...910.24     37.7     21     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
268A4IF63    744   TRIM2_BOVIN Tripartite motif-containing prote...650.26     37.7     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
269Q9FHG8    210   ATL50_ARATH Putative RING-H2 finger protein A...530.27     37     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
270Q9SG96    181   ATL72_ARATH RING-H2 finger protein ATL72 OS=A...600.27     36.6     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
271D2GXS7    744   TRIM2_AILME Tripartite motif-containing prote...650.28     37.7     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
records
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