Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q28GL3    416   RNFT1_XENTR RING finger and transmembrane dom...550.063     39.7     33     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
212Q7XI08    513   XB34_ORYSJ Probable E3 ubiquitin-protein liga...700.063     39.7     30     44
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
213P28284    825   ICP0_HHV2H E3 ubiquitin-protein ligase ICP0 O...570.066     39.7     30     46
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
214Q3UF64    445   RNFT2_MOUSE RING finger and transmembrane dom...610.067     39.7     30     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
215Q3U2C5    394   RN149_MOUSE E3 ubiquitin-protein ligase RNF14...340.067     39.3     44     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
216P0C041    310   ATL53_ARATH Putative RING-H2 finger protein A...830.067     39.3     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
217P09309    467   IE61_VZVD E3 ubiquitin-protein ligase IE61 OS...1030.067     39.7     25     42
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
218Q8L9T5    304   ATL2_ARATH RING-H2 finger protein ATL2 OS=Ara...790.068     39.3     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IDA:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
219P08393    775   ICP0_HHV11 E3 ubiquitin-protein ligase ICP0 O...750.07     39.7     23     45GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:AgBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; TAS:AgBase.::GO:0000209; P:protein polyubiquitination; IDA:AgBase.::GO:0019046; P:reactivation of latent virus; TAS:AgBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0034340; P:response to type I interferon; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
220Q9M0R6    302   ATL35_ARATH Putative RING-H2 finger protein A...520.074     38.9     31     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
221Q05568    337   PEX10_YEAST Peroxisome biogenesis factor 10 O...290.077     39.3     45     59GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IMP:SGD.
222Q6ZNA4    994   RN111_HUMAN E3 ubiquitin-protein ligase Arkad...290.078     39.7     45     69GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:BHF-UCL.
223Q99ML9    989   RN111_MOUSE E3 ubiquitin-protein ligase Arkad...290.079     39.7     45     69GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:MGI.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007389; P:pattern specification process; IMP:MGI.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IMP:BHF-UCL.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IMP:BHF-UCL.
224Q8WWF5    429   ZNRF4_HUMAN Zinc/RING finger protein 4 OS=Hom...730.079     39.3     26     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
225Q5R476    986   RN111_PONAB E3 ubiquitin-protein ligase Arkad...290.08     39.7     45     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
226Q9SUS5    157   RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B...580.083     37.7     31     50
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
227B1AUE5    324   PEX10_MOUSE Peroxisome biogenesis factor 10 O...930.088     38.9     25     35GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
228Q84TF5    174   RHA4A_ARATH RING-H2 zinc finger protein RHA4a...550.089     38.1     31     51
GO:0008270; F:zinc ion binding; IEA:InterPro.
229P38239    180   YBR2_YEAST Uncharacterized RING finger protei...240.096     38.1     54     63
GO:0008270; F:zinc ion binding; IEA:InterPro.
230Q9LS99    220   ATL77_ARATH RING-H2 finger protein ATL77 OS=A...1150.1     38.1     27     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
231P22682    913   CBL_MOUSE E3 ubiquitin-protein ligase CBL OS=...260.1     39.3     54     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
232Q9SUS4    159   RHA1A_ARATH RING-H2 zinc finger protein RHA1a...800.1     37.4     28     45
GO:0008270; F:zinc ion binding; IEA:InterPro.
233Q9UUF0    306   PEX10_SCHPO Peroxisome biogenesis factor 10 O...520.11     38.5     35     42GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
234Q5RF74    428   RN128_PONAB E3 ubiquitin-protein ligase RNF12...640.11     38.9     27     48GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
235Q8TEB7    428   RN128_HUMAN E3 ubiquitin-protein ligase RNF12...640.11     38.9     27     48GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
236Q17551    3766   RPM1_CAEEL E3 ubiquitin-protein ligase rpm-1 ...860.12     39.3     23     44GO:0030424; C:axon; IDA:WormBase.::GO:0031594; C:neuromuscular junction; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0043409; P:negative regulation of MAPK cascade; IGI:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0031647; P:regulation of protein stability; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
237Q6P4U6    215   ZNRF1_DANRE E3 ubiquitin-protein ligase znrf1...550.12     38.1     33     51GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
238Q75DC2    328   ASR1_ASHGO Alcohol-sensitive RING finger prot...410.12     38.5     37     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
239P22681    906   CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=...260.12     38.9     54     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC.
240P12672    412   RAPSN_MOUSE 43 kDa receptor-associated protei...460.13     38.5     41     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0033130; F:acetylcholine receptor binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043525; P:positive regulation of neuron apoptotic process; IMP:MGI.
241Q29RU0    431   RN128_BOVIN E3 ubiquitin-protein ligase RNF12...870.13     38.5     23     46GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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