Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL013C
Length:
551
Number of sequences:
5887
Description:
YOL013C HRD1 SGDID:S000005373, Chr XV from 303035-301380, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q810L3    664   CHFR_MOUSE E3 ubiquitin-protein ligase CHFR O...550.008     42.7     40     44GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
122P0C035    310   ATL60_ARATH RING-H2 finger protein ATL60 OS=A...1070.008     42.4     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
123Q8GT75    236   NIP1_ARATH NEP1-interacting protein 1 OS=Arab...630.008     42     32     49GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
124Q9LY41    334   ATL4_ARATH E3 ubiquitin-protein ligase ATL4 O...750.008     42.4     27     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
125Q7T0Q3    312   R126A_XENLA RING finger protein 126-A OS=Xeno...280.008     42.4     46     71
GO:0008270; F:zinc ion binding; IEA:InterPro.
126Q9LRB7    325   EL5_ORYSJ E3 ubiquitin-protein ligase EL5 OS=...540.008     42.4     33     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IMP:UniProtKB.::GO:0048364; P:root development; IMP:UniProtKB.
127Q32L15    230   RN141_BOVIN RING finger protein 141 OS=Bos ta...570.008     41.6     33     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
128Q8R1Z9    327   RN121_MOUSE RING finger protein 121 OS=Mus mu...580.009     42     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
129Q2XNS1    231   RN141_CANFA RING finger protein 141 OS=Canis ...570.009     41.6     33     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
130Q6IV56    222   RN141_DANRE RING finger protein 141 OS=Danio ...780.009     41.6     27     40
GO:0008270; F:zinc ion binding; IEA:InterPro.
131Q8L649    248   BB_ARATH E3 ubiquitin ligase BIG BROTHER OS=A...320.009     41.6     41     59
GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048437; P:floral organ development; IMP:TAIR.::GO:0046621; P:negative regulation of organ growth; IMP:TAIR.::GO:0051865; P:protein autoubiquitination; IDA:TAIR.
132Q5R7K8    230   RN141_PONAB RING finger protein 141 OS=Pongo ...570.009     41.6     33     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
133Q8WVD5    230   RN141_HUMAN RING finger protein 141 OS=Homo s...570.009     41.6     33     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
134Q8WU17    664   RN139_HUMAN E3 ubiquitin-protein ligase RNF13...970.01     42.4     23     39GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0070613; P:regulation of protein processing; IDA:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
135Q6P360    327   RN121_XENTR RING finger protein 121 OS=Xenopu...580.01     42     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
136Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...1000.01     42.4     25     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
137Q8HXW8    326   PEX10_MACFA Peroxisome biogenesis factor 10 O...820.01     42     23     41GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.
GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016558; P:protein import into peroxisome matrix; ISS:UniProtKB.
138A5WW08    637   CHFR_DANRE E3 ubiquitin-protein ligase CHFR O...550.01     42.4     40     44GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
139Q5RF77    571   CHFR_PONAB E3 ubiquitin-protein ligase CHFR O...550.01     42.4     40     44GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
140Q9ULT6    936   ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Hom...1080.011     42.4     28     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
141Q96EP1    664   CHFR_HUMAN E3 ubiquitin-protein ligase CHFR O...550.011     42.4     40     44GO:0016605; C:PML body; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
142Q99MB7    230   RN141_MOUSE RING finger protein 141 OS=Mus mu...570.011     41.2     33     42
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IDA:MGI.
143Q6DD32    327   RN121_XENLA RING finger protein 121 OS=Xenopu...580.011     41.6     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
144Q9C7I1    327   ATL34_ARATH RING-H2 finger protein ATL34 OS=A...630.011     41.6     30     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
145Q80XL1    496   CBLC_MOUSE Signal transduction protein CBL-C ...820.011     42     32     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
146Q5M7Z0    435   RNFT1_HUMAN RING finger and transmembrane dom...670.011     42     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
147Q6IV57    230   RN141_RAT RING finger protein 141 OS=Rattus n...570.011     41.2     33     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
148Q9BV68    326   RN126_HUMAN RING finger protein 126 OS=Homo s...1490.011     41.6     24     40
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
149Q5BIY5    695   RN145_XENLA RING finger protein 145 OS=Xenopu...1090.012     42.4     20     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
150Q9BWF2    469   TRAIP_HUMAN TRAF-interacting protein OS=Homo ...860.012     42     34     42GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.
151Q6P256    626   CHFR_XENTR E3 ubiquitin-protein ligase CHFR O...280.012     42     54     57GO:0016605; C:PML body; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
records
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