YOL006C TOP1 SGDID:S000005366, Chr XV from 315387-313078, Genome Release 64-1-1, reverse complement, Verified ORF, "Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination"