Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL004W
Length:
1536
Number of sequences:
5887
Description:
YOL004W SIN3 SGDID:S000005364, Chr XV from 316938-321548, Genome Release 64-1-1, Verified ORF, "Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P22579    1536   SIN3_YEAST Transcriptional regulatory protein...15360     3192     100     100GO:0033698; C:Rpd3L complex; IDA:SGD.::GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.::GO:0032221; C:Rpd3S complex; IDA:SGD.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; IMP:SGD.::GO:0003714; F:transcription corepressor activity; IMP:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0016575; P:histone deacetylation; IMP:SGD.::GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:SGD.::GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031939; P:negative regulation of chromatin silencing at telomere; IMP:SGD.::GO:0051038; P:negative regulation of transcription during meiosis; IMP:SGD.::GO:0016479; P:negative regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IGI:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q09750    1522   PST1_SCHPO Paired amphipathic helix protein p...3484e-53     209     41     51GO:0005721; C:centromeric heterochromatin; IDA:PomBase.::GO:0033698; C:Rpd3L complex; IDA:PomBase.::GO:0032221; C:Rpd3S complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0003714; F:transcription corepressor activity; ISS:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0016575; P:histone deacetylation; IGI:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q62141    1098   SIN3B_MOUSE Paired amphipathic helix protein ...670.00006     51.6     34     55GO:0030849; C:autosome; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000805; C:X chromosome; IDA:MGI.::GO:0001741; C:XY body; IDA:UniProtKB.::GO:0000806; C:Y chromosome; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0048738; P:cardiac muscle tissue development; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007519; P:skeletal muscle tissue development; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q60520    1274   SIN3A_MOUSE Paired amphipathic helix protein ...2820.00000003     62.4     26     45GO:0000776; C:kinetochore; IDA:MGI.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IPI:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IGI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:MGI.
GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0071333; P:cellular response to glucose stimulus; IDA:MGI.::GO:0006260; P:DNA replication; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0051329; P:interphase of mitotic cell cycle; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051595; P:response to methylglyoxal; IDA:MGI.
5Q96ST3    1273   SIN3A_HUMAN Paired amphipathic helix protein ...2800.00000003     62.8     25     46GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0016580; C:Sin3 complex; IDA:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
6O75182    1162   SIN3B_HUMAN Paired amphipathic helix protein ...670.00006     51.6     34     55GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O74755    1154   PST3_SCHPO Paired amphipathic helix protein p...2731e-46     187     42     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0070210; C:Rpd3L-Expanded complex; IDA:PomBase.::GO:0032221; C:Rpd3S complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; NAS:PomBase.::GO:0006342; P:chromatin silencing; ISS:PomBase.::GO:0006303; P:double-strand break repair via nonhomologous end joining; ISS:PomBase.::GO:0016575; P:histone deacetylation; IC:PomBase.
8O13919    1075   PST2_SCHPO Paired amphipathic helix protein p...1030.000000002     66.2     32     56GO:0032221; C:Rpd3S complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; ISS:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0006342; P:chromatin silencing; ISS:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0016575; P:histone deacetylation; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9O04539    1326   SNL4_ARATH Paired amphipathic helix protein S...860.009     44.7     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10O48686    1330   SNL3_ARATH Paired amphipathic helix protein S...620.008     44.7     31     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q9SRH9    1372   SNL1_ARATH Paired amphipathic helix protein S...711.8     37     28     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q9XIE1    1162   SNL5_ARATH Paired amphipathic helix protein S...828.9     34.7     22     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q9LFQ3    1367   SNL2_ARATH Paired amphipathic helix protein S...711.3     37.4     28     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q9XIK6    1173   SNL6_ARATH Paired amphipathic helix protein S...800.12     40.8     28     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q9SZ67    1895   WRK19_ARATH Probable WRKY transcription facto...662.4     36.6     30     52GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q3T8J9    2241   GON4L_HUMAN GON-4-like protein OS=Homo sapien...690.76     38.1     28     57GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
17P41014    162   ATPF_BACCA ATP synthase subunit b OS=Bacillus...1021.1     35.8     30     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
18C0S7Q7    309   SHO1_PARBP High osmolarity signaling protein ...961.5     36.6     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
19C1GJ63    302   SHO1_PARBD High osmolarity signaling protein ...961.5     36.6     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
20Q9DB00    2260   GON4L_MOUSE GON-4-like protein OS=Mus musculu...1085.7     35.4     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
21Q15149    4684   PLEC_HUMAN Plectin OS=Homo sapiens (Human). G...1882.1     37     23     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
22Q54XT6    783   GACR_DICDI Rho GTPase-activating protein gacR...783     36.2     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
23P23351    508   RMS5_NEUCR Ribosomal protein S5, mitochondria...843.1     35.8     31     48GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:UniProtKB-KW.
24Q1B550    443   ATPFD_MYCSS ATP synthase subunit b-delta OS=M...693.2     35.8     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
GO:0003824; F:catalytic activity; IEA:UniProtKB-KW.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
25A1UJY7    443   ATPFD_MYCSK ATP synthase subunit b-delta OS=M...693.2     35.8     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
GO:0003824; F:catalytic activity; IEA:UniProtKB-KW.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
26A3Q3B4    443   ATPFD_MYCSJ ATP synthase subunit b-delta OS=M...693.2     35.8     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
GO:0003824; F:catalytic activity; IEA:UniProtKB-KW.::GO:0046933; F:hydrogen ion transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
27Q7NCS0    174   ATPX_GLOVI ATP synthase subunit b' OS=Gloeoba...733.2     34.7     36     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045263; C:proton-transporting ATP synthase complex, coupling factor F(o); IEA:UniProtKB-KW.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
28B4S6S2    397   PGK_PROA2 Phosphoglycerate kinase OS=Prosthec...984     35.4     37     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004618; F:phosphoglycerate kinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
29Q96PE2    2063   ARHGH_HUMAN Rho guanine nucleotide exchange f...1424.9     35.4     29     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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