Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR074C
Length:
378
Number of sequences:
5887
Description:
YNR074C AIF1 SGDID:S000005357, Chr XIV from 778738-777602, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q1CNP4    466   STHA_YERPN Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
92A9R6N5    466   STHA_YERPG Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
93Q8ZA97    466   STHA_YERPE Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
94B2JZF3    466   STHA_YERPB Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
95Q1CBU5    466   STHA_YERPA Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
96A7FD10    466   STHA_YERP3 Soluble pyridine nucleotide transh...2170.006     42     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
97Q9Z773    461   DLDH_CHLPN Dihydrolipoyl dehydrogenase OS=Chl...2300.007     42     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
98P39040    491   TYTR_CRIFA Trypanothione reductase OS=Crithid...1980.007     42     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
99Q9BRQ8    373   AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Ho...3030.008     41.6     21     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IDA:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
GO:0008637; P:apoptotic mitochondrial changes; NAS:UniProtKB.::GO:0030261; P:chromosome condensation; IDA:UniProtKB.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.
100Q8CPV5    402   Y635_STAES NADH dehydrogenase-like protein SE...2450.009     41.6     25     42
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
101A1JI37    466   STHA_YERE8 Soluble pyridine nucleotide transh...2000.009     41.6     21     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
102P21880    470   DLDH1_BACSU Dihydrolipoyl dehydrogenase OS=Ba...1520.011     41.2     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
103P42435    805   NASD_BACSU Nitrite reductase [NAD(P)H] OS=Bac...2310.011     41.6     26     42
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0008942; F:nitrite reductase [NAD(P)H activity; IEA:EC.
GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.]
104Q5HQM1    402   Y527_STAEQ NADH dehydrogenase-like protein SE...2450.011     41.2     25     41
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
105O95831    613   AIFM1_HUMAN Apoptosis-inducing factor 1, mito...1690.017     40.8     24     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB.::GO:0044455; C:mitochondrial membrane part; IMP:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; TAS:ProtInc.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:ProtInc.::GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.::GO:0030182; P:neuron differentiation; IDA:UniProtKB.
106Q9Z0X1    612   AIFM1_MOUSE Apoptosis-inducing factor 1, mito...1690.02     40.8     25     46GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005792; C:microsome; IDA:MGI.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; TAS:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; TAS:MGI.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IMP:UniProtKB.::GO:0008637; P:apoptotic mitochondrial changes; TAS:MGI.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.
107Q9Y6N5    450   SQRD_HUMAN Sulfide:quinone oxidoreductase, mi...3110.021     40.4     24     43GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
GO:0070224; F:sulfide:quinone oxidoreductase activity; TAS:Reactome.
GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
108B2TWF7    466   STHA_SHIB3 Soluble pyridine nucleotide transh...2210.029     40     20     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
109A2RIB7    446   NAOX_LACLM NADH oxidase OS=Lactococcus lactis...3080.033     39.7     21     44GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003954; F:NADH dehydrogenase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
110P39050    491   TYTR_LEIDO Trypanothione reductase OS=Leishma...1940.034     39.7     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0015042; F:trypanothione-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
111P33009    409   TERPA_PSESP Terpredoxin reductase OS=Pseudomo...1790.036     39.7     26     45GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
112Q83MI1    466   STHA_SHIFL Soluble pyridine nucleotide transh...2210.036     39.7     19     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
113Q7MQ83    466   STHA_VIBVY Soluble pyridine nucleotide transh...2060.039     39.7     22     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
114Q8DD46    466   STHA_VIBVU Soluble pyridine nucleotide transh...2060.039     39.7     22     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
115A5W4E9    410   TODA_PSEP1 Toluene 1,2-dioxygenase system fer...2170.049     39.3     25     42GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008860; F:ferredoxin-NAD+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
116D0VWY5    463   GASHR_MARGR Glutathione amide reductase OS=Ma...2170.05     39.3     22     41GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004362; F:glutathione-disulfide reductase activity; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006749; P:glutathione metabolic process; IEA:InterPro.
117Q9JM53    612   AIFM1_RAT Apoptosis-inducing factor 1, mitoch...1710.054     39.3     27     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
118A4VMU6    464   STHA_PSEU5 Soluble pyridine nucleotide transh...2250.058     38.9     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
119P43784    478   DLDH_HAEIN Dihydrolipoyl dehydrogenase OS=Hae...2210.064     38.9     20     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
120Q70G58    515   NTRC_ORYSJ Thioredoxin reductase NTRC OS=Oryz...3140.068     38.9     23     39
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB.::GO:0019430; P:removal of superoxide radicals; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
121P37062    447   NAPE_ENTFA NADH peroxidase OS=Enterococcus fa...2210.068     38.9     23     43GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016692; F:NADH peroxidase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
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