Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR031C
Length:
1579
Number of sequences:
5887
Description:
YNR031C SSK2 SGDID:S000005314, Chr XIV from 685433-680694, Genome Release 64-1-1, reverse complement, Verified ORF, "MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901Q10KY3    600   CAMK1_ORYSJ Calcium/calmodulin-dependent seri...3074e-18     93.6     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
902P13863    303   CDK1_CHICK Cyclin-dependent kinase 1 OS=Gallu...3145e-18     90.9     25     43GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
903Q6DGS3    554   KC2D2_DANRE Calcium/calmodulin-dependent prot...3085e-18     93.6     26     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
904O23145    431   KSG2_ARATH Shaggy-related protein kinase beta...3695e-18     92.4     24     44GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
905Q8C0V0    766   TLK1_MOUSE Serine/threonine-protein kinase to...2955e-18     94     27     41GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0001672; P:regulation of chromatin assembly or disassembly; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
906Q08CW1    697   TLK2_XENTR Serine/threonine-protein kinase to...2965e-18     94     27     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
907Q9GN62    617   PAR4_CAEEL Serine/threonine-protein kinase pa...2955e-18     93.6     25     46GO:0005938; C:cell cortex; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:WormBase.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IGI:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.
908Q9NRH2    765   SNRK_HUMAN SNF-related serine/threonine-prote...2915e-18     94     25     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
909P16912    583   KDC2_DROME Protein kinase DC2 OS=Drosophila m...2315e-18     93.6     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.
910Q6Z8C8    459   CDKF4_ORYSJ Cyclin-dependent kinase F-4 OS=Or...2295e-18     92.4     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
911P92199    1173   ROCK_CAEEL Rho-associated protein kinase let-...2805e-18     94.4     29     43GO:0005913; C:cell-cell adherens junction; IDA:WormBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0043292; C:contractile fiber; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; TAS:WormBase.
912Q9P7J8    569   GAD8_SCHPO Serine/threonine-protein kinase ga...2755e-18     93.6     28     41
GO:0005524; F:ATP binding; IC:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0031142; P:induction of conjugation upon nitrogen starvation; IGI:PomBase.::GO:2000750; P:negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; TAS:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
913Q03407    766   PKH1_YEAST Serine/threonine-protein kinase PK...2825e-18     94     25     46GO:0005829; C:cytosol; IDA:SGD.::GO:0032126; C:eisosome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
914P53894    756   CBK1_YEAST Serine/threonine-protein kinase CB...3195e-18     94     26     41GO:0005938; C:cell cortex; IDA:SGD.::GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0007118; P:budding cell apical bud growth; IMP:SGD.::GO:2000695; P:cytokinetic cell separation involved in cell cycle cytokinesis; IMP:SGD.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IGI:SGD.
915Q62726    629   ICK_RAT Serine/threonine-protein kinase ICK O...2985e-18     93.6     27     45GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
916A2VDZ4    893   PLK4_BOVIN Serine/threonine-protein kinase PL...2926e-18     94     27     44GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
917Q07785    288   CDC2H_PLAFK Cell division control protein 2 h...2376e-18     90.5     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
918P61075    288   CDC2H_PLAF7 Cell division control protein 2 h...2376e-18     90.5     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
919Q1ECX4    697   TLK2_DANRE Serine/threonine-protein kinase to...3106e-18     93.6     27     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
920Q6SA08    328   TSSK4_HUMAN Testis-specific serine/threonine-...2946e-18     90.9     25     47
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
921Q6FP74    773   CBK1_CANGA Serine/threonine-protein kinase CB...3156e-18     94     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
922Q621J7    709   ZYG1_CAEBR Probable serine/threonine-protein ...3126e-18     93.6     29     43GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
923Q64261    326   CDK6_MOUSE Cyclin-dependent kinase 6 OS=Mus m...3386e-18     90.9     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0002244; P:hemopoietic progenitor cell differentiation; IMP:MGI.::GO:0060218; P:hemopoietic stem cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0033077; P:T cell differentiation in thymus; IMP:MGI.
924P34100    714   PKD1_DICDI Developmentally-regulated protein ...2316e-18     93.6     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
925Q9DG02    475   KCC2D_XENLA Calcium/calmodulin-dependent prot...3076e-18     92.4     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
926Q09136    385   AAPK1_PIG 5'-AMP-activated protein kinase cat...2676e-18     91.3     27     47GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
927Q9FVS6    420   KSG4_ARATH Shaggy-related protein kinase delt...2486e-18     92     27     47GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
928Q6ZWH5    1172   NEK10_HUMAN Serine/threonine-protein kinase N...2986e-18     94.4     27     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
929Q03114    292   CDK5_RAT Cyclin-dependent kinase 5 OS=Rattus ...3236e-18     90.5     25     43GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; TAS:RGD.::GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IDA:RGD.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:RGD.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:RGD.::GO:0006913; P:nucleocytoplasmic transport; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0045055; P:regulated secretory pathway; IMP:RGD.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0009611; P:response to wounding; IMP:RGD.::GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; IMP:RGD.
930O55047    718   TLK2_MOUSE Serine/threonine-protein kinase to...2966e-18     93.6     27     42GO:0005882; C:intermediate filament; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001672; P:regulation of chromatin assembly or disassembly; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
931Q1DUU8    364   HOG1_COCIM Mitogen-activated protein kinase H...3256e-18     90.9     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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