Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR026C
Length:
471
Number of sequences:
5887
Description:
YNR026C SEC12 SGDID:S000005309, Chr XIV from 674689-673274, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF), activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P11655    471   SEC12_YEAST Guanine nucleotide-exchange facto...4710     956     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000299; C:integral to membrane of membrane fraction; IDA:SGD.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005090; F:Sar guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0003400; P:regulation of COPII vesicle coating; IDA:SGD.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
2Q6FIY2    459   SEC12_CANGA Guanine nucleotide-exchange facto...4195e-131     394     51     70GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
3P25365    1065   SED4_YEAST Putative guanine nucleotide-exchan...3883e-106     346     45     66GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.
GO:0005101; F:Sar GTPase activator activity; IDA:SGD.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0003400; P:regulation of COPII vesicle coating; IDA:SGD.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
4Q6FPI5    1029   SED4_CANGA Putative guanine nucleotide-exchan...4054e-99     326     45     66GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
5Q10659    395   SPO14_SCHPO Membrane glycoprotein spo14 OS=Sc...3840.000000001     63.5     25     43GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.
GO:0032120; P:ascospore-type prospore membrane assembly; IMP:PomBase.::GO:0031322; P:ascospore-type prospore-specific spindle pole body remodeling; IMP:PomBase.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
6Q7ZVA0    513   SMU1_DANRE WD40 repeat-containing protein SMU...1860.021     40.8     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
7Q8N1V2    620   WDR16_HUMAN WD repeat-containing protein 16 O...730.18     38.1     36     49GO:0005737; C:cytoplasm; IDA:HPA.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.
8Q95JL5    571   WDR16_MACFA WD repeat-containing protein 16 O...730.18     38.1     36     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
9Q39221    393   STLP2_ARATH SEC12-like protein 2 OS=Arabidops...1950.19     37.7     23     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
10Q498F0    912   WDR44_XENLA WD repeat-containing protein 44 O...1030.29     37.4     30     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
11Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...2052     35     23     41
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
12Q5RHI5    647   DTL_DANRE Denticleless protein homolog OS=Dan...560.65     36.2     34     55GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:ZFIN.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
13P0CS36    435   HAT2_CRYNJ Histone acetyltransferase type B s...600.78     35.8     37     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
14P0CS37    435   HAT2_CRYNB Histone acetyltransferase type B s...600.78     35.8     37     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
15Q9N9X3    716   CTX80_EUPOC Ciliary WD repeat-containing prot...890.83     35.8     28     51
16Q8NA23    367   WDR31_HUMAN WD repeat-containing protein 31 O...1161.5     34.7     28     42
17P78706    604   RCO1_NEUCR Transcriptional repressor rco-1 OS...1931.8     34.7     23     41
GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18A8WVX8    327   EIF3I_CAEBR Eukaryotic translation initiation...2181.8     34.7     18     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
19Q6NVE8    915   WDR44_MOUSE WD repeat-containing protein 44 O...1031.9     34.7     29     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
20Q5DFU0    352   CIAO1_SCHJA Probable cytosolic iron-sulfur pr...751.9     34.7     33     48
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
21Q9R037    908   WDR44_RAT WD repeat-containing protein 44 OS=...1031.9     34.7     29     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0017137; F:Rab GTPase binding; IDA:RGD.
GO:0030334; P:regulation of cell migration; IMP:RGD.
22C4YFX2    511   TUP1_CANAW Transcriptional repressor TUP1 OS=...1622.1     34.7     23     41
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P0CY34    512   TUP1_CANAL Transcriptional repressor TUP1 OS=...1622.1     34.7     23     41GO:0005625; C:soluble fraction; IDA:CGD.
GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q91WQ5    589   TAF5L_MOUSE TAF5-like RNA polymerase II p300/...692.1     34.7     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q5JSH3    913   WDR44_HUMAN WD repeat-containing protein 44 O...1032.2     34.7     29     55GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
26Q54NA2    372   ATG18_DICDI Autophagy-related protein 18 OS=D...1282.4     34.3     27     51GO:0005829; C:cytosol; ISS:dictyBase.::GO:0070772; C:PAS complex; IBA:RefGenome.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:RefGenome.
GO:0016236; P:macroautophagy; IBA:RefGenome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
27Q9UUG8    598   TUP12_SCHPO Transcriptional repressor tup12 O...1712.5     34.3     27     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IDA:PomBase.
GO:0043156; P:chromatin remodeling in response to cation stress; IMP:PomBase.::GO:0006342; P:chromatin silencing; IMP:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1142.6     34.3     26     46
29B9LSS4    240   RL2_HALLT 50S ribosomal protein L2P OS=ACAM 3...1583.1     33.5     26     41GO:0015934; C:large ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
30O75529    589   TAF5L_HUMAN TAF5-like RNA polymerase II p300/...454.4     33.5     38     62GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
31Q06078    939   UTP21_YEAST U3 small nucleolar RNA-associated...735.8     33.1     32     48GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD.::GO:0032040; C:small-subunit processome; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0042274; P:ribosomal small subunit biogenesis; IC:SGD.::GO:0006364; P:rRNA processing; IGI:SGD.
records
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