Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR016C
Length:
2233
Number of sequences:
5887
Description:
YNR016C ACC1 SGDID:S000005299, Chr XIV from 661374-654673, Genome Release 64-1-1, reverse complement, Verified ORF, "Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q00955    2233   ACAC_YEAST Acetyl-CoA carboxylase OS=Saccharo...22330     4618     100     100GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0003989; F:acetyl-CoA carboxylase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IMP:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006998; P:nuclear envelope organization; TAS:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.
2P78820    2280   ACAC_SCHPO Acetyl-CoA carboxylase OS=Schizosa...22410     2746     59     75GO:0005829; C:cytosol; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:PomBase.::GO:0005524; F:ATP binding; ISS:PomBase.::GO:0004075; F:biotin carboxylase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0042759; P:long-chain fatty acid biosynthetic process; IMP:PomBase.::GO:0007088; P:regulation of mitosis; IMP:PomBase.
3A6ZMR9    2273   HFA1_YEAS7 Acetyl-CoA carboxylase, mitochondr...22280     2525     55     73GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
4P32874    2273   HFA1_YEAST Acetyl-CoA carboxylase, mitochondr...22270     2521     55     72GO:0005739; C:mitochondrion; IDA:SGD.
GO:0003989; F:acetyl-CoA carboxylase activity; IGI:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IGI:SGD.
5C8ZF72    2273   HFA1_YEAS8 Acetyl-CoA carboxylase, mitochondr...22270     2517     55     72GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
6C7GRE4    2273   HFA1_YEAS2 Acetyl-CoA carboxylase, mitochondr...22260     2512     55     72GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
7B3LM95    2273   HFA1_YEAS1 Acetyl-CoA carboxylase, mitochondr...22260     2509     55     72GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
8P11029    2324   ACAC_CHICK Acetyl-CoA carboxylase OS=Gallus g...22440     1941     46     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
9O00763    2458   ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo ...22480     1919     46     63GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.
10Q13085    2346   ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo ...22690     1904     45     63GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
11Q5SWU9    2345   ACACA_MOUSE Acetyl-CoA carboxylase 1 OS=Mus m...22650     1901     45     63GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.::GO:0055088; P:lipid homeostasis; IMP:MGI.::GO:0044268; P:multicellular organismal protein metabolic process; IMP:MGI.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI.
12Q28559    2346   ACACA_SHEEP Acetyl-CoA carboxylase 1 OS=Ovis ...22650     1899     45     63GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
13Q9TTS3    2346   ACACA_BOVIN Acetyl-CoA carboxylase 1 OS=Bos t...22650     1896     45     63GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
14P11497    2345   ACACA_RAT Acetyl-CoA carboxylase 1 OS=Rattus ...22650     1877     45     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0003989; F:acetyl-CoA carboxylase activity; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006084; P:acetyl-CoA metabolic process; IDA:RGD.::GO:0006633; P:fatty acid biosynthetic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IMP:RGD.
15Q54J08    2282   ACAC_DICDI Acetyl-CoA carboxylase OS=Dictyost...23190     1729     42     60GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005739; C:mitochondrion; ISS:dictyBase.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; ISS:dictyBase.::GO:0006998; P:nuclear envelope organization; ISS:dictyBase.::GO:0006606; P:protein import into nucleus; ISS:dictyBase.
16F4I1L3    2355   ACC2_ARATH Acetyl-CoA carboxylase 2 OS=Arabid...22770     1590     40     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
17Q38970    2254   ACC1_ARATH Acetyl-CoA carboxylase 1 OS=Arabid...22850     1588     40     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030497; P:fatty acid elongation; IMP:TAIR.::GO:0010072; P:primary shoot apical meristem specification; IMP:TAIR.::GO:0009735; P:response to cytokinin stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.
18Q8S6N5    2267   ACC1_ORYSJ Acetyl-CoA carboxylase 1 OS=Oryza ...22990     1582     39     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
19B9FK36    2327   ACC2_ORYSJ Acetyl-CoA carboxylase 2 OS=Oryza ...22240     1548     41     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
20O27939    491   PYCA_METTH Pyruvate carboxylase subunit A OS=...5139e-73     259     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
21P05165    728   PCCA_HUMAN Propionyl-CoA carboxylase alpha ch...7393e-69     255     29     47GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:ProtInc.
GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.::GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
22Q06862    447   ACCC_NOSS1 Biotin carboxylase OS=Nostoc sp. (...5208e-69     246     32     49
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
23Q91ZA3    724   PCCA_MOUSE Propionyl-CoA carboxylase alpha ch...7397e-66     244     29     47GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IMP:MGI.
24P14882    737   PCCA_RAT Propionyl-CoA carboxylase alpha chai...7394e-65     243     29     47GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:RGD.
GO:0009063; P:cellular amino acid catabolic process; TAS:RGD.::GO:0009062; P:fatty acid catabolic process; TAS:RGD.
25Q5I0C3    715   MCCA_RAT Methylcrotonoyl-CoA carboxylase subu...5498e-65     241     32     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
26Q2QMG2    737   MCCA_ORYSJ Methylcrotonoyl-CoA carboxylase su...7482e-63     237     29     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
27Q96RQ3    725   MCCA_HUMAN Methylcrotonoyl-CoA carboxylase su...7279e-63     235     28     46GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; NAS:UniProtKB.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; NAS:UniProtKB.
GO:0006768; P:biotin metabolic process; NAS:UniProtKB.::GO:0006552; P:leucine catabolic process; NAS:UniProtKB.
28O34544    444   ACCC2_BACSU Biotin carboxylase 2 OS=Bacillus ...5093e-62     227     32     50
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
29P49787    450   ACCC1_BACSU Biotin carboxylase 1 OS=Bacillus ...5165e-61     223     32     49
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
30Q42523    734   MCCA_ARATH Methylcrotonoyl-CoA carboxylase su...7512e-60     228     28     43GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0050897; F:cobalt ion binding; IDA:TAIR.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IDA:TAIR.
GO:0006552; P:leucine catabolic process; IDA:TAIR.
31Q58626    501   PYCA_METJA Pyruvate carboxylase subunit A OS=...5231e-59     221     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
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