Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR006W
Length:
622
Number of sequences:
5887
Description:
YNR006W VPS27 SGDID:S000005289, Chr XIV from 636986-638854, Genome Release 64-1-1, Verified ORF, "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q54IL5    1697   UGT52_DICDI UDP-sugar-dependent glycosyltrans...580.00000007     59.7     41     60
GO:0051507; F:beta-sitosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0051505; F:cholesterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051506; F:ergosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051508; F:stigmasterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051509; F:tomatidine UDP-glucosyltransferase activity; IDA:dictyBase.
GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
92Q3TB82    279   PKHF1_MOUSE Pleckstrin homology domain-contai...650.00000009     57.4     45     58GO:0005764; C:lysosome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:MGI.
93Q96P53    400   WDFY2_HUMAN WD repeat and FYVE domain-contain...720.0000002     57     42     51
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
94Q8BUB4    400   WDFY2_MOUSE WD repeat and FYVE domain-contain...720.0000003     57     42     51
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
95Q810J8    777   ZFYV1_MOUSE Zinc finger FYVE domain-containin...830.000001     55.5     40     53GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
96Q9HBF4    777   ZFYV1_HUMAN Zinc finger FYVE domain-containin...830.0000009     55.8     40     53GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
97O60784    492   TOM1_HUMAN Target of Myb protein 1 OS=Homo sa...1390.0000004     56.6     27     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
98O88746    492   TOM1_MOUSE Target of Myb protein 1 OS=Mus mus...1660.0000005     56.2     28     51GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
99Q5RFL4    789   ZFYV1_PONAB Zinc finger FYVE domain-containin...830.000001     55.8     40     53GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
100Q923U0    474   TM1L1_MOUSE TOM1-like protein 1 OS=Mus muscul...1490.0000005     56.2     28     50GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
GO:0030295; F:protein kinase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:MGI.
101P34756    2278   FAB1_YEAST 1-phosphatidylinositol 3-phosphate...610.0000007     56.6     41     52GO:0010008; C:endosome membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0070772; C:PAS complex; IDA:SGD.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
102Q80UZ0    1219   FGD5_MOUSE FYVE, RhoGEF and PH domain-contain...570.0000008     56.2     42     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
103Q7ZUV1    247   PKHF2_DANRE Pleckstrin homology domain-contai...640.0000008     54.3     47     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
104B0G126    2656   FYV1_DICDI 1-phosphatidylinositol 3-phosphate...630.0000009     56.2     41     57GO:0005739; C:mitochondrion; ISS:dictyBase.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
105Q9Y7M3    293   YNT3_SCHPO FYVE-type zinc finger-containing p...550.000001     54.3     44     56GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
106Q9BQS8    1478   FYCO1_HUMAN FYVE and coiled-coil domain-conta...710.000001     55.5     37     56GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0072383; P:plus-end-directed vesicle transport along microtubule; IMP:UniProtKB.
107F1LM81    475   TM1L1_RAT TOM1-like protein 1 OS=Rattus norve...1450.000002     54.3     27     50GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
108Q9Y2I7    2098   FYV1_HUMAN 1-phosphatidylinositol 3-phosphate...500.000002     55.1     40     54GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:HGNC.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:EC.::GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; TAS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
109Q9Z1T6    2097   FYV1_MOUSE 1-phosphatidylinositol 3-phosphate...500.000002     54.7     40     54GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:EC.::GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
110O96838    1809   FYV1_DROME Putative 1-phosphatidylinositol 3-...590.000003     54.3     41     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; ISS:UniProtKB.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IMP:FlyBase.::GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0008333; P:endosome to lysosome transport; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
111Q6ZNL6    1462   FGD5_HUMAN FYVE, RhoGEF and PH domain-contain...510.000005     53.5     45     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
112Q8IWB7    410   WDFY1_HUMAN WD repeat and FYVE domain-contain...690.000005     52.8     38     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
113Q2KIY3    410   WDFY1_BOVIN WD repeat and FYVE domain-contain...690.000005     52.8     38     52GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
114Q10410    510   YD85_SCHPO Probable ADP-ribosylation factor-b...1500.000006     52.8     30     53GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005802; C:trans-Golgi network; ISS:PomBase.
GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.
115Q7Z3T8    1539   ZFY16_HUMAN Zinc finger FYVE domain-containin...610.000009     52.8     43     56GO:0031901; C:early endosome membrane; TAS:Reactome.
GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IMP:UniProtKB.
GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0016197; P:endosome transport; IMP:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0016050; P:vesicle organization; NAS:UniProtKB.
116Q22712    1006   MTMR3_CAEEL Myotublarin-related protein 3 OS=...690.00001     52.4     38     57
GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:WormBase.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:WormBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:WormBase.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0045807; P:positive regulation of endocytosis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
117O75674    476   TM1L1_HUMAN TOM1-like protein 1 OS=Homo sapie...1510.00001     52     26     48GO:0005829; C:cytosol; IDA:HGNC.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; TAS:ProtInc.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; TAS:HGNC.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; NAS:HGNC.
118Q8VDC1    1437   FYCO1_MOUSE FYVE and coiled-coil domain-conta...870.00001     52     30     51GO:0005776; C:autophagic vacuole; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:InterPro.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0072383; P:plus-end-directed vesicle transport along microtubule; ISS:UniProtKB.
119Q80U44    1528   ZFY16_MOUSE Zinc finger FYVE domain-containin...610.00002     51.6     43     56GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
120Q54TC3    585   SLOB1_DICDI Probable inactive serine/threonin...850.00004     50.4     35     52
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
121Q0U6X7    618   HSE1_PHANO Class E vacuolar protein-sorting m...1540.0002     48.5     25     46GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
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