Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR006W
Length:
622
Number of sequences:
5887
Description:
YNR006W VPS27 SGDID:S000005289, Chr XIV from 636986-638854, Genome Release 64-1-1, Verified ORF, "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q0P4S0    951   LST2_XENTR Lateral signaling target protein 2...630.0000000000002     77     48     65GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
32Q6ZPK7    905   LST2_MOUSE Lateral signaling target protein 2...670.0000000000002     77     46     64GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
33B4PRU6    984   LST2_DROYA Lateral signaling target protein 2...740.0000000000003     76.6     45     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
34B4IC49    975   LST2_DROSE Lateral signaling target protein 2...740.0000000000003     76.6     45     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
35Q9HCC9    887   LST2_HUMAN Lateral signaling target protein 2...810.0000000000003     76.6     44     60GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB.
36B3P851    981   LST2_DROER Lateral signaling target protein 2...740.0000000000003     76.6     45     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
37Q9VB70    989   LST2_DROME Lateral signaling target protein 2...740.0000000000003     76.6     45     59
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
38Q92783    540   STAM1_HUMAN Signal transducing adapter molecu...1410.0000000000004     75.9     33     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
39B4JHI7    1115   LST2_DROGR Lateral signaling target protein 2...640.0000000000004     76.6     50     64
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
40P70297    548   STAM1_MOUSE Signal transducing adapter molecu...1410.0000000000005     75.5     33     53GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
41Q7QAJ2    1161   LST2_ANOGA Lateral signaling target protein 2...630.000000000001     75.1     51     63
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
42B4K982    1051   LST2_DROMO Lateral signaling target protein 2...640.000000000001     74.7     48     61GO:0016020; C:membrane; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:InterPro.
43B4M140    1052   LST2_DROVI Lateral signaling target protein 2...640.000000000002     74.7     48     61
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
44A0JMD2    969   LST2_DANRE Lateral signaling target protein 2...630.000000000002     74.3     48     65GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
45B4NFJ7    993   LST2_DROWI Lateral signaling target protein 2...630.000000000002     73.9     49     60
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
46Q15075    1411   EEA1_HUMAN Early endosome antigen 1 OS=Homo s...630.000000000003     73.9     44     59GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:UniProtKB.
GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB.::GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB.::GO:0006906; P:vesicle fusion; IMP:UniProtKB.
47Q8R4C2    606   RUFY2_MOUSE RUN and FYVE domain-containing pr...590.000000000003     73.2     56     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
48B3MT31    985   LST2_DROAN Lateral signaling target protein 2...600.000000000003     73.6     50     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
49Q5R5R4    606   RUFY2_PONAB RUN and FYVE domain-containing pr...590.000000000009     71.6     54     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
50B4G2G5    1009   LST2_DROPE Lateral signaling target protein 2...600.00000000001     72     48     62
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
51Q8BL66    1411   EEA1_MOUSE Early endosome antigen 1 OS=Mus mu...540.00000000001     71.6     50     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0005969; C:serine-pyruvate aminotransferase complex; IDA:MGI.
GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:UniProtKB.
52Q8WXA3    655   RUFY2_HUMAN RUN and FYVE domain-containing pr...590.00000000001     71.2     54     68GO:0005634; C:nucleus; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
53Q810B6    1169   ANFY1_MOUSE Ankyrin repeat and FYVE domain-co...620.00000000003     70.5     42     58GO:0010008; C:endosome membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; NAS:UniProtKB.
54A8XJZ8    651   LST2_CAEBR Lateral signaling target protein 2...600.00000000005     69.3     43     63
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
55Q8BIJ7    712   RUFY1_MOUSE RUN and FYVE domain-containing pr...840.00000000006     68.9     45     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.
56Q9P2R3    1169   ANFY1_HUMAN Ankyrin repeat and FYVE domain-co...580.00000000006     69.3     41     60GO:0010008; C:endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
57Q96T51    708   RUFY1_HUMAN RUN and FYVE domain-containing pr...840.00000000006     68.9     45     54GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
58Q9TZD0    661   LST2_CAEEL Lateral signaling target protein 2...600.0000000001     68.6     42     63
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.
GO:0040027; P:negative regulation of vulval development; IMP:WormBase.
59Q6ZV73    1430   FGD6_HUMAN FYVE, RhoGEF and PH domain-contain...790.0000000001     68.2     44     58GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
60Q91XS1    1190   MTMR4_MOUSE Myotubularin-related protein 4 OS...580.0000000002     67.4     45     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
61O93436    468   STAM2_CHICK Signal transducing adapter molecu...1490.0000000003     66.2     30     50GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
records
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