rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q0P4S0 | 951 | LST2_XENTR Lateral signaling target protein 2... | 63 | 0.0000000000002 | 77 | 48 | 65 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 32 | Q6ZPK7 | 905 | LST2_MOUSE Lateral signaling target protein 2... | 67 | 0.0000000000002 | 77 | 46 | 64 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 33 | B4PRU6 | 984 | LST2_DROYA Lateral signaling target protein 2... | 74 | 0.0000000000003 | 76.6 | 45 | 59 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 34 | B4IC49 | 975 | LST2_DROSE Lateral signaling target protein 2... | 74 | 0.0000000000003 | 76.6 | 45 | 59 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 35 | Q9HCC9 | 887 | LST2_HUMAN Lateral signaling target protein 2... | 81 | 0.0000000000003 | 76.6 | 44 | 60 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB. | 36 | B3P851 | 981 | LST2_DROER Lateral signaling target protein 2... | 74 | 0.0000000000003 | 76.6 | 45 | 59 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 37 | Q9VB70 | 989 | LST2_DROME Lateral signaling target protein 2... | 74 | 0.0000000000003 | 76.6 | 45 | 59 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 38 | Q92783 | 540 | STAM1_HUMAN Signal transducing adapter molecu... | 141 | 0.0000000000004 | 75.9 | 33 | 53 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 39 | B4JHI7 | 1115 | LST2_DROGR Lateral signaling target protein 2... | 64 | 0.0000000000004 | 76.6 | 50 | 64 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 40 | P70297 | 548 | STAM1_MOUSE Signal transducing adapter molecu... | 141 | 0.0000000000005 | 75.5 | 33 | 53 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 41 | Q7QAJ2 | 1161 | LST2_ANOGA Lateral signaling target protein 2... | 63 | 0.000000000001 | 75.1 | 51 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 42 | B4K982 | 1051 | LST2_DROMO Lateral signaling target protein 2... | 64 | 0.000000000001 | 74.7 | 48 | 61 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:InterPro. | 43 | B4M140 | 1052 | LST2_DROVI Lateral signaling target protein 2... | 64 | 0.000000000002 | 74.7 | 48 | 61 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 44 | A0JMD2 | 969 | LST2_DANRE Lateral signaling target protein 2... | 63 | 0.000000000002 | 74.3 | 48 | 65 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB. | 45 | B4NFJ7 | 993 | LST2_DROWI Lateral signaling target protein 2... | 63 | 0.000000000002 | 73.9 | 49 | 60 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 46 | Q15075 | 1411 | EEA1_HUMAN Early endosome antigen 1 OS=Homo s... | 63 | 0.000000000003 | 73.9 | 44 | 59 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:UniProtKB. | | | | | | | | | | GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB.::GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB.::GO:0006906; P:vesicle fusion; IMP:UniProtKB. | 47 | Q8R4C2 | 606 | RUFY2_MOUSE RUN and FYVE domain-containing pr... | 59 | 0.000000000003 | 73.2 | 56 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | B3MT31 | 985 | LST2_DROAN Lateral signaling target protein 2... | 60 | 0.000000000003 | 73.6 | 50 | 62 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 49 | Q5R5R4 | 606 | RUFY2_PONAB RUN and FYVE domain-containing pr... | 59 | 0.000000000009 | 71.6 | 54 | 68 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | B4G2G5 | 1009 | LST2_DROPE Lateral signaling target protein 2... | 60 | 0.00000000001 | 72 | 48 | 62 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 51 | Q8BL66 | 1411 | EEA1_MOUSE Early endosome antigen 1 OS=Mus mu... | 54 | 0.00000000001 | 71.6 | 50 | 63 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0005969; C:serine-pyruvate aminotransferase complex; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB. | 52 | Q8WXA3 | 655 | RUFY2_HUMAN RUN and FYVE domain-containing pr... | 59 | 0.00000000001 | 71.2 | 54 | 68 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 53 | Q810B6 | 1169 | ANFY1_MOUSE Ankyrin repeat and FYVE domain-co... | 62 | 0.00000000003 | 70.5 | 42 | 58 | GO:0010008; C:endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB. | 54 | A8XJZ8 | 651 | LST2_CAEBR Lateral signaling target protein 2... | 60 | 0.00000000005 | 69.3 | 43 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 55 | Q8BIJ7 | 712 | RUFY1_MOUSE RUN and FYVE domain-containing pr... | 84 | 0.00000000006 | 68.9 | 45 | 52 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI. | 56 | Q9P2R3 | 1169 | ANFY1_HUMAN Ankyrin repeat and FYVE domain-co... | 58 | 0.00000000006 | 69.3 | 41 | 60 | GO:0010008; C:endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 57 | Q96T51 | 708 | RUFY1_HUMAN RUN and FYVE domain-containing pr... | 84 | 0.00000000006 | 68.9 | 45 | 54 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 58 | Q9TZD0 | 661 | LST2_CAEEL Lateral signaling target protein 2... | 60 | 0.0000000001 | 68.6 | 42 | 63 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase. | | | | | | | | | | GO:0040027; P:negative regulation of vulval development; IMP:WormBase. | 59 | Q6ZV73 | 1430 | FGD6_HUMAN FYVE, RhoGEF and PH domain-contain... | 79 | 0.0000000001 | 68.2 | 44 | 58 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 60 | Q91XS1 | 1190 | MTMR4_MOUSE Myotubularin-related protein 4 OS... | 58 | 0.0000000002 | 67.4 | 45 | 62 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 61 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 149 | 0.0000000003 | 66.2 | 30 | 50 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |