Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNR006W
Length:
622
Number of sequences:
5887
Description:
YNR006W VPS27 SGDID:S000005289, Chr XIV from 636986-638854, Genome Release 64-1-1, Verified ORF, "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q0U6X7    618   HSE1_PHANO Class E vacuolar protein-sorting m...1540.0002     48.5     25     46GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
122Q9H1K0    784   RBNS5_HUMAN Rabenosyn-5 OS=Homo sapiens (Huma...790.0002     48.5     39     57GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
123Q80Y56    783   RBNS5_MOUSE Rabenosyn-5 OS=Mus musculus (Mous...790.0002     48.1     39     57GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
124O95405    1425   ZFYV9_HUMAN Zinc finger FYVE domain-containin...590.0003     48.1     42     53GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
125Q06651    286   PIB1_YEAST E3 ubiquitin-protein ligase PIB1 O...680.0007     45.4     28     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
126A1DFN5    603   HSE1_NEOFI Class E vacuolar protein-sorting m...1330.0007     46.2     22     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
127Q4P5J4    593   HSE1_USTMA Class E vacuolar protein-sorting m...1340.0008     46.2     25     50GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
128Q5BIM5    404   ZFY27_BOVIN Protrudin OS=Bos taurus (Bovine)....580.001     45.4     34     50GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB.
129O74749    373   HSE1_SCHPO Class E vacuolar protein-sorting m...1420.001     45.4     27     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
130P32609    515   PEP7_YEAST Vacuolar segregation protein PEP7 ...460.001     45.4     46     57GO:0010009; C:external side of endosome membrane; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:SGD.::GO:0006906; P:vesicle fusion; IMP:SGD.
131O13786    536   PEP7_SCHPO Vacuolar segregation protein pep7 ...680.13     38.9     32     49GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.::GO:0006906; P:vesicle fusion; ISS:PomBase.
132A4RF61    718   HSE1_MAGO7 Class E vacuolar protein-sorting m...1320.002     45.1     22     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
133A8XXC7    417   WDFY2_CAEBR WD repeat and FYVE domain-contain...680.002     44.3     32     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
134A1CEK6    599   HSE1_ASPCL Class E vacuolar protein-sorting m...1330.002     44.7     20     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
135Q0CJU8    597   HSE1_ASPTN Class E vacuolar protein-sorting m...1330.002     44.7     21     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
136Q18964    415   WDFY2_CAEEL WD repeat and FYVE domain-contain...680.003     44.3     31     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IMP:WormBase.
137O59722    1932   FAB1_SCHPO 1-phosphatidylinositol 3-phosphate...530.003     44.7     32     53GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase.
GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IDA:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.
GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.::GO:0007033; P:vacuole organization; ISS:PomBase.::GO:0016192; P:vesicle-mediated transport; IGI:PomBase.
138A2QW93    611   HSE1_ASPNC Class E vacuolar protein-sorting m...1330.004     43.9     21     47GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
139O88387    766   FGD4_RAT FYVE, RhoGEF and PH domain-containin...740.006     43.5     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:MGI.::GO:0008360; P:regulation of cell shape; IMP:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
140Q91ZT5    766   FGD4_MOUSE FYVE, RhoGEF and PH domain-contain...740.006     43.5     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
141Q8BY35    655   FGD2_MOUSE FYVE, RhoGEF and PH domain-contain...520.007     43.1     40     54GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
142Q96M96    766   FGD4_HUMAN FYVE, RhoGEF and PH domain-contain...770.008     43.1     34     48GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
143P87157    533   YB0G_SCHPO Probable ADP-ribosylation factor-b...720.01     42.4     31     56GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; ISS:PomBase.
GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.
144Q7S6J4    745   HSE1_NEUCR Class E vacuolar protein-sorting m...1320.011     42.4     23     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
145Q96K21    471   ZFY19_HUMAN Zinc finger FYVE domain-containin...660.012     42.4     33     50
GO:0008270; F:zinc ion binding; IEA:InterPro.
146Q7Z6J4    655   FGD2_HUMAN FYVE, RhoGEF and PH domain-contain...550.012     42.4     40     51GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
147Q5T4F4    411   ZFY27_HUMAN Protrudin OS=Homo sapiens (Human)...560.012     42     36     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IDA:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB.
148Q5R7K2    411   ZFY27_PONAB Protrudin OS=Pongo abelii (Sumatr...560.013     42     36     46GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB.
149P38817    585   GGA2_YEAST ADP-ribosylation factor-binding pr...1360.015     42     26     49GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
150P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...1530.017     42     22     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
151P0CR79    660   HSE1_CRYNB Class E vacuolar protein-sorting m...1530.02     41.6     22     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
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