rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q0U6X7 | 618 | HSE1_PHANO Class E vacuolar protein-sorting m... | 154 | 0.0002 | 48.5 | 25 | 46 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 122 | Q9H1K0 | 784 | RBNS5_HUMAN Rabenosyn-5 OS=Homo sapiens (Huma... | 79 | 0.0002 | 48.5 | 39 | 57 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 123 | Q80Y56 | 783 | RBNS5_MOUSE Rabenosyn-5 OS=Mus musculus (Mous... | 79 | 0.0002 | 48.1 | 39 | 57 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 124 | O95405 | 1425 | ZFYV9_HUMAN Zinc finger FYVE domain-containin... | 59 | 0.0003 | 48.1 | 42 | 53 | GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 125 | Q06651 | 286 | PIB1_YEAST E3 ubiquitin-protein ligase PIB1 O... | 68 | 0.0007 | 45.4 | 28 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 126 | A1DFN5 | 603 | HSE1_NEOFI Class E vacuolar protein-sorting m... | 133 | 0.0007 | 46.2 | 22 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 127 | Q4P5J4 | 593 | HSE1_USTMA Class E vacuolar protein-sorting m... | 134 | 0.0008 | 46.2 | 25 | 50 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 128 | Q5BIM5 | 404 | ZFY27_BOVIN Protrudin OS=Bos taurus (Bovine).... | 58 | 0.001 | 45.4 | 34 | 50 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 129 | O74749 | 373 | HSE1_SCHPO Class E vacuolar protein-sorting m... | 142 | 0.001 | 45.4 | 27 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 130 | P32609 | 515 | PEP7_YEAST Vacuolar segregation protein PEP7 ... | 46 | 0.001 | 45.4 | 46 | 57 | GO:0010009; C:external side of endosome membrane; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:SGD.::GO:0006906; P:vesicle fusion; IMP:SGD. | 131 | O13786 | 536 | PEP7_SCHPO Vacuolar segregation protein pep7 ... | 68 | 0.13 | 38.9 | 32 | 49 | GO:0005794; C:Golgi apparatus; IDA:PomBase. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006904; P:vesicle docking involved in exocytosis; ISS:PomBase.::GO:0006906; P:vesicle fusion; ISS:PomBase. | 132 | A4RF61 | 718 | HSE1_MAGO7 Class E vacuolar protein-sorting m... | 132 | 0.002 | 45.1 | 22 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 133 | A8XXC7 | 417 | WDFY2_CAEBR WD repeat and FYVE domain-contain... | 68 | 0.002 | 44.3 | 32 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 134 | A1CEK6 | 599 | HSE1_ASPCL Class E vacuolar protein-sorting m... | 133 | 0.002 | 44.7 | 20 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 135 | Q0CJU8 | 597 | HSE1_ASPTN Class E vacuolar protein-sorting m... | 133 | 0.002 | 44.7 | 21 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 136 | Q18964 | 415 | WDFY2_CAEEL WD repeat and FYVE domain-contain... | 68 | 0.003 | 44.3 | 31 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IMP:WormBase. | 137 | O59722 | 1932 | FAB1_SCHPO 1-phosphatidylinositol 3-phosphate... | 53 | 0.003 | 44.7 | 32 | 53 | GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase. | | | | | | | | | | GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IDA:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:PomBase. | | | | | | | | | | GO:0044267; P:cellular protein metabolic process; IEA:InterPro.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.::GO:0007033; P:vacuole organization; ISS:PomBase.::GO:0016192; P:vesicle-mediated transport; IGI:PomBase. | 138 | A2QW93 | 611 | HSE1_ASPNC Class E vacuolar protein-sorting m... | 133 | 0.004 | 43.9 | 21 | 47 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 139 | O88387 | 766 | FGD4_RAT FYVE, RhoGEF and PH domain-containin... | 74 | 0.006 | 43.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; IMP:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:MGI.::GO:0008360; P:regulation of cell shape; IMP:RGD.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 140 | Q91ZT5 | 766 | FGD4_MOUSE FYVE, RhoGEF and PH domain-contain... | 74 | 0.006 | 43.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0030032; P:lamellipodium assembly; IDA:MGI.::GO:0030035; P:microspike assembly; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 141 | Q8BY35 | 655 | FGD2_MOUSE FYVE, RhoGEF and PH domain-contain... | 52 | 0.007 | 43.1 | 40 | 54 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 142 | Q96M96 | 766 | FGD4_HUMAN FYVE, RhoGEF and PH domain-contain... | 77 | 0.008 | 43.1 | 34 | 48 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 143 | P87157 | 533 | YB0G_SCHPO Probable ADP-ribosylation factor-b... | 72 | 0.01 | 42.4 | 31 | 56 | GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase. | 144 | Q7S6J4 | 745 | HSE1_NEUCR Class E vacuolar protein-sorting m... | 132 | 0.011 | 42.4 | 23 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 145 | Q96K21 | 471 | ZFY19_HUMAN Zinc finger FYVE domain-containin... | 66 | 0.012 | 42.4 | 33 | 50 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 146 | Q7Z6J4 | 655 | FGD2_HUMAN FYVE, RhoGEF and PH domain-contain... | 55 | 0.012 | 42.4 | 40 | 51 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 147 | Q5T4F4 | 411 | ZFY27_HUMAN Protrudin OS=Homo sapiens (Human)... | 56 | 0.012 | 42 | 36 | 46 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IDA:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 148 | Q5R7K2 | 411 | ZFY27_PONAB Protrudin OS=Pongo abelii (Sumatr... | 56 | 0.013 | 42 | 36 | 46 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 149 | P38817 | 585 | GGA2_YEAST ADP-ribosylation factor-binding pr... | 136 | 0.015 | 42 | 26 | 49 | GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; IDA:SGD. | | | | | | | | | | GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD. | 150 | P0CR78 | 660 | HSE1_CRYNJ Class E vacuolar protein-sorting m... | 153 | 0.017 | 42 | 22 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 151 | P0CR79 | 660 | HSE1_CRYNB Class E vacuolar protein-sorting m... | 153 | 0.02 | 41.6 | 22 | 48 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. |