rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P42837 | 879 | FIG4_YEAST Polyphosphoinositide phosphatase O... | 879 | 0 | 1832 | 100 | 100 | GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0070772; C:PAS complex; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD. | 2 | Q91WF7 | 907 | FIG4_MOUSE Polyphosphoinositide phosphatase O... | 736 | 1e-166 | 515 | 40 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0048666; P:neuron development; IMP:MGI.::GO:0046488; P:phosphatidylinositol metabolic process; IMP:MGI.::GO:0043473; P:pigmentation; IMP:MGI.::GO:0007033; P:vacuole organization; IMP:MGI. | 3 | Q92562 | 907 | FIG4_HUMAN Polyphosphoinositide phosphatase O... | 735 | 5e-166 | 513 | 40 | 58 | GO:0010008; C:endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW. | 4 | Q7Z9H9 | 832 | FIG4_SCHPO Polyphosphoinositide phosphatase O... | 694 | 2e-165 | 509 | 42 | 57 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0019898; C:extrinsic to membrane; ISS:PomBase.::GO:0000329; C:fungal-type vacuole membrane; ISS:PomBase. | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0000753; P:cell morphogenesis involved in conjugation with cellular fusion; ISS:PomBase.::GO:0046488; P:phosphatidylinositol metabolic process; NAS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase. | 5 | Q6GM29 | 586 | SAC1_XENLA Phosphatidylinositide phosphatase ... | 496 | 3e-54 | 202 | 32 | 47 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 6 | Q9W0I6 | 592 | SAC1_DROME Phosphatidylinositide phosphatase ... | 479 | 2e-53 | 200 | 33 | 50 | GO:0030424; C:axon; IDA:FlyBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:FlyBase.::GO:0071683; C:sensory dendrite; IDA:FlyBase. | | | | | | | | | | GO:0052866; F:phosphatidylinositol phosphate phosphatase activity; IDA:FlyBase. | | | | | | | | | | GO:0016199; P:axon midline choice point recognition; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0046329; P:negative regulation of JNK cascade; IMP:FlyBase. | 7 | Q9ES21 | 587 | SAC1_RAT Phosphatidylinositide phosphatase SA... | 491 | 4e-50 | 190 | 32 | 46 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:RGD. | | | | | | | | | | GO:0034593; F:phosphatidylinositol bisphosphate phosphatase activity; IDA:RGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:RGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD. | 8 | A6QL88 | 587 | SAC1_BOVIN Phosphatidylinositide phosphatase ... | 491 | 6e-50 | 189 | 32 | 46 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 9 | A1L244 | 586 | SAC1A_DANRE Phosphatidylinositide phosphatase... | 504 | 1e-48 | 186 | 31 | 47 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 10 | Q9EP69 | 587 | SAC1_MOUSE Phosphatidylinositide phosphatase ... | 491 | 2e-47 | 182 | 31 | 46 | | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 11 | Q5R921 | 587 | SAC1_PONAB Phosphatidylinositide phosphatase ... | 488 | 3e-47 | 181 | 32 | 46 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 12 | Q9NTJ5 | 587 | SAC1_HUMAN Phosphatidylinositide phosphatase ... | 488 | 5e-47 | 181 | 31 | 46 | GO:0005794; C:Golgi apparatus; IDA:LIFEdb. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 13 | A4VCH0 | 586 | SAC1B_DANRE Phosphatidylinositide phosphatase... | 512 | 2e-46 | 179 | 30 | 46 | GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016791; F:phosphatase activity; ISS:UniProtKB. | | | | | | | | | | | 14 | O60162 | 598 | YG23_SCHPO Uncharacterized protein C19F5.03 O... | 487 | 2e-44 | 173 | 31 | 45 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.::GO:0030173; C:integral to Golgi membrane; ISS:PomBase.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase. | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0016192; P:vesicle-mediated transport; ISS:PomBase. | 15 | Q55AW9 | 581 | SAC1_DICDI Phosphatidylinositide phosphatase ... | 482 | 2e-43 | 170 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; ISS:dictyBase.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:dictyBase.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; ISS:dictyBase. | | | | | | | | | | GO:0048017; P:inositol lipid-mediated signaling; ISS:dictyBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:dictyBase. | 16 | P32368 | 623 | SAC1_YEAST Phosphoinositide phosphatase SAC1 ... | 487 | 3e-40 | 161 | 29 | 45 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0030173; C:integral to Golgi membrane; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.::GO:0035339; C:SPOTS complex; IDA:UniProtKB. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD. | 17 | P50942 | 1183 | INP52_YEAST Polyphosphatidylinositol phosphat... | 419 | 5e-37 | 154 | 28 | 47 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 18 | O18964 | 1324 | SYNJ1_BOVIN Synaptojanin-1 OS=Bos taurus (Bov... | 518 | 9e-34 | 144 | 27 | 45 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 19 | O43426 | 1573 | SYNJ1_HUMAN Synaptojanin-1 OS=Homo sapiens (H... | 518 | 1e-33 | 144 | 27 | 44 | | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 20 | O14127 | 611 | YF51_SCHPO Uncharacterized protein C3C7.01c O... | 483 | 2e-33 | 140 | 28 | 44 | GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0000139; C:Golgi membrane; ISS:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase. | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; ISS:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase. | 21 | Q62910 | 1574 | SYNJ1_RAT Synaptojanin-1 OS=Rattus norvegicus... | 518 | 5e-32 | 138 | 26 | 44 | GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0014015; P:positive regulation of gliogenesis; IMP:RGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0032526; P:response to retinoic acid; IMP:RGD. | 22 | Q8CHC4 | 1574 | SYNJ1_MOUSE Synaptojanin-1 OS=Mus musculus (M... | 518 | 6e-32 | 138 | 25 | 44 | GO:0030118; C:clathrin coat; TAS:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI.::GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. | 23 | A8E7C5 | 1120 | SAC2_DANRE Phosphatidylinositide phosphatase ... | 461 | 1e-31 | 137 | 29 | 44 | | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | | 24 | Q12271 | 1107 | INP53_YEAST Polyphosphatidylinositol phosphat... | 519 | 1e-31 | 137 | 25 | 44 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0042598; C:vesicular fraction; IDA:SGD. | | | | | | | | | | GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:SGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IDA:SGD. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 25 | O55207 | 1496 | SYNJ2_RAT Synaptojanin-2 OS=Rattus norvegicus... | 535 | 5e-31 | 135 | 28 | 42 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0005881; C:cytoplasmic microtubule; IDA:RGD.::GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0032587; C:ruffle membrane; IDA:RGD. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0052744; F:phosphatidylinositol monophosphate phosphatase activity; IDA:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:RGD.::GO:0048312; P:intracellular distribution of mitochondria; IDA:RGD.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 26 | Q9D2G5 | 1434 | SYNJ2_MOUSE Synaptojanin-2 OS=Mus musculus (M... | 535 | 2e-30 | 134 | 27 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 27 | O15056 | 1496 | SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens (H... | 534 | 2e-30 | 133 | 27 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 28 | Q8CDA1 | 1132 | SAC2_MOUSE Phosphatidylinositide phosphatase ... | 451 | 3e-26 | 119 | 27 | 42 | | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | | 29 | O43001 | 1076 | SYJ1_SCHPO Inositol-1,4,5-trisphosphate 5-pho... | 546 | 1e-24 | 114 | 26 | 42 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 30 | Q9Y2H2 | 1132 | SAC2_HUMAN Phosphatidylinositide phosphatase ... | 448 | 2e-24 | 114 | 26 | 42 | | | | | | | | | | | GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro. | | | | | | | | | | | 31 | P40559 | 946 | INP51_YEAST Phosphatidylinositol 4,5-bisphosp... | 423 | 0.0000000002 | 68.2 | 23 | 40 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. |