Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL317W
Length:
465
Number of sequences:
5887
Description:
YNL317W PFS2 SGDID:S000005261, Chr XIV from 40619-42016, Genome Release 64-1-1, Verified ORF, "Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...2680.0002     47.4     21     37GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
452P53196    417   RPN14_YEAST 26S proteasome regulatory subunit...736.9     32.7     26     44GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
453P49027    334   GBLPA_ORYSJ Guanine nucleotide-binding protei...2820.00002     50.1     24     40GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IMP:UniProtKB.::GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.
454Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...2680.000008     52     20     37
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
455Q5ZMV9    705   WDR24_CHICK WD repeat-containing protein 24 O...2500.000000002     63.5     23     44
456B4LJT7    331   CIAO1_DROVI Probable cytosolic iron-sulfur pr...1880.019     40.8     22     40
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
457Q8SRK1    384   HAT2_ENCCU Histone acetyltransferase type B s...1292.6     33.9     21     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
458P49026    326   GBLP_TOBAC Guanine nucleotide-binding protein...2660.0000002     56.2     24     43
459Q54MP8    2200   Y5837_DICDI Bromodomain and WD repeat-contain...1170.89     35.8     22     41
460Q7ZYQ6    445   DCA13_XENLA DDB1- and CUL4-associated factor ...2590.000000002     62.8     23     43GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
461Q2UA71    436   HAT2_ASPOR Histone acetyltransferase type B s...2480.000000003     62.4     24     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
462Q38942    349   RAE1L_ARATH Rae1-like protein At1g80670 OS=Ar...2540.000000003     62     20     42GO:0080008; C:CUL4 RING ubiquitin ligase complex; IPI:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005635; C:nuclear envelope; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.
463P0CS32    341   EIF3I_CRYNJ Eukaryotic translation initiation...791.5     34.7     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
464P0CS33    341   EIF3I_CRYNB Eukaryotic translation initiation...791.5     34.7     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
465Q3KQ62    314   WDR83_XENLA WD repeat domain-containing prote...1594.3     33.1     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
466Q15269    919   PWP2_HUMAN Periodic tryptophan protein 2 homo...2650.000000005     62.4     22     42GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0004871; F:signal transducer activity; TAS:ProtInc.
467O13282    643   TAF5_SCHPO Transcription initiation factor TF...1100.32     37.4     18     39GO:0005829; C:cytosol; IDA:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.::GO:0005669; C:transcription factor TFIID complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; IC:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:PomBase.
468Q6L4F8    336   GBLPB_ORYSJ Guanine nucleotide-binding protei...3230.0000001     57     23     39
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
469Q5FVN8    476   WSDU1_RAT WD repeat, SAM and U-box domain-con...1070.013     41.6     25     36GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
470Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...2680.000008     52     21     37GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
471Q6H8D6    910   COB23_ORYSJ Putative coatomer subunit beta'-3...1780.062     39.7     26     46GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
472Q9CX97    388   WDR55_MOUSE WD repeat-containing protein 55 O...3010.000000004     62     22     38GO:0005737; C:cytoplasm; IMP:UniProtKB.::GO:0005730; C:nucleolus; IMP:UniProtKB.
GO:0006364; P:rRNA processing; IMP:UniProtKB.
473O55029    905   COPB2_MOUSE Coatomer subunit beta' OS=Mus mus...2490.0000002     57.4     20     39
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
474Q8TED0    518   UTP15_HUMAN U3 small nucleolar RNA-associated...2020.05     39.7     23     42GO:0005737; C:cytoplasm; IDA:LIFEdb.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
475Q4R4I8    906   COPB2_MACFA Coatomer subunit beta' OS=Macaca ...2490.0000002     57.4     20     39GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
476C5MJE8    490   LIS1_CANTT Nuclear distribution protein PAC1 ...2800.000000005     62     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
477Q5R664    906   COPB2_PONAB Coatomer subunit beta' OS=Pongo a...2490.0000002     57     20     39GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
478Q4P5F5    455   CIAO1_USTMA Probable cytosolic iron-sulfur pr...510.13     38.5     35     57
479P35606    906   COPB2_HUMAN Coatomer subunit beta' OS=Homo sa...2490.0000002     57     20     39GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0030126; C:COPI vesicle coat; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
480P35605    906   COPB2_BOVIN Coatomer subunit beta' OS=Bos tau...2490.0000002     57     20     39GO:0030126; C:COPI vesicle coat; IDA:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:AgBase.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
481Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...1600.0000003     56.6     24     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
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