Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL312W
Length:
273
Number of sequences:
5887
Description:
YNL312W RFA2 SGDID:S000005256, Chr XIV from 48287-48293,48402-49216, Genome Release 64-1-1, Verified ORF, "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P26754    273   RFA2_YEAST Replication factor A protein 2 OS=...2730     567     100     100GO:0000781; C:chromosome, telomeric region; IMP:SGD.::GO:0000794; C:condensed nuclear chromosome; IDA:SGD.::GO:0005662; C:DNA replication factor A complex; IDA:SGD.
GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0000724; P:double-strand break repair via homologous recombination; IGI:SGD.::GO:0045184; P:establishment of protein localization; IMP:SGD.::GO:0030491; P:heteroduplex formation; IDA:SGD.::GO:0006289; P:nucleotide-excision repair; IMP:SGD.::GO:0016567; P:protein ubiquitination; IPI:SGD.::GO:0007131; P:reciprocal meiotic recombination; IPI:SGD.::GO:0000722; P:telomere maintenance via recombination; IPI:SGD.::GO:0007004; P:telomere maintenance via telomerase; IMP:SGD.
2Q92373    279   RFA2_SCHPO Replication factor A protein 2 OS=...2466e-20     90.5     32     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005662; C:DNA replication factor A complex; IDA:PomBase.
GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0065007; P:biological regulation; NAS:PomBase.::GO:0006310; P:DNA recombination; ISS:PomBase.::GO:0006281; P:DNA repair; ISS:PomBase.::GO:0006269; P:DNA replication, synthesis of RNA primer; ISS:PomBase.
3Q5RC43    270   RFA2_PONAB Replication protein A 32 kDa subun...2673e-17     82.4     28     45GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
4P15927    270   RFA2_HUMAN Replication protein A 32 kDa subun...2674e-17     82     28     45GO:0005662; C:DNA replication factor A complex; IPI:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0000075; P:cell cycle checkpoint; TAS:Reactome.::GO:0000730; P:DNA recombinase assembly; TAS:Reactome.::GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.::GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
5Q63528    270   RFA2_RAT Replication protein A 32 kDa subunit...2610.00000000000001     75.1     27     44GO:0005662; C:DNA replication factor A complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0047485; F:protein N-terminus binding; IMP:RGD.::GO:0003697; F:single-stranded DNA binding; IDA:RGD.
GO:0006284; P:base-excision repair; NAS:RGD.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IC:RGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
6Q62193    270   RFA2_MOUSE Replication protein A 32 kDa subun...2660.00000000000001     74.7     27     43GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
7Q13156    261   RFA4_HUMAN Replication protein A 30 kDa subun...2560.000000000004     67.8     25     40GO:0005662; C:DNA replication factor A complex; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
8Q4R804    368   STN1_MACFA CST complex subunit STN1 OS=Macaca...1970.17     36.6     23     43GO:0000784; C:nuclear chromosome, telomeric region; ISS:UniProtKB.
GO:0043047; F:single-stranded telomeric DNA binding; ISS:UniProtKB.
GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
9Q8K2X3    378   STN1_MOUSE CST complex subunit STN1 OS=Mus mu...1990.22     36.2     24     44GO:0070188; C:Stn1-Ten1 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043047; F:single-stranded telomeric DNA binding; ISS:UniProtKB.
GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
10Q9H668    368   STN1_HUMAN CST complex subunit STN1 OS=Homo s...1970.34     35.8     23     43GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043047; F:single-stranded telomeric DNA binding; IDA:UniProtKB.
GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.::GO:0010833; P:telomere maintenance via telomere lengthening; IMP:UniProtKB.
11Q9X2E6    388   RIBBA_THEMA Riboflavin biosynthesis protein r...540.64     35     35     54
GO:0008686; F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity; IEA:EC.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003935; F:GTP cyclohydrolase II activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0009231; P:riboflavin biosynthetic process; IEA:UniProtKB-KW.
12Q23697    258   RFA2_CRIFA Replication protein A 28 kDa subun...2810.8     34.3     23     38GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13Q08DB2    370   STN1_BOVIN CST complex subunit STN1 OS=Bos ta...1991.1     34.3     25     40
GO:0043047; F:single-stranded telomeric DNA binding; ISS:UniProtKB.
GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
14Q6AYD2    408   STN1_RAT CST complex subunit STN1 OS=Rattus n...1992.4     33.1     22     42
GO:0043047; F:single-stranded telomeric DNA binding; ISS:UniProtKB.
GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.::GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
15Q8YW42    412   EX7L_NOSS1 Exodeoxyribonuclease 7 large subun...532.6     33.1     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
GO:0008855; F:exodeoxyribonuclease VII activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006308; P:DNA catabolic process; IEA:InterPro.
16Q9KDN6    320   YHAM_BACHD 3'-5' exoribonuclease yhaM OS=9153...774.5     32.3     25     42
GO:0000175; F:3'-5'-exoribonuclease activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
17Q1RJT5    357   RF1_RICBR Peptide chain release factor 1 OS=R...886.6     31.6     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
18A8GXI1    357   RF1_RICB8 Peptide chain release factor 1 OS=R...886.6     31.6     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
19P26208    448   BGLA_CLOTH Beta-glucosidase A OS=Clostridium ...457.8     31.6     38     56
GO:0008422; F:beta-glucosidase activity; IEA:EC.::GO:0043169; F:cation binding; IEA:InterPro.
GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
20Q6K669    598   AMPL2_ORYSJ Leucine aminopeptidase 2, chlorop...2037.9     31.6     24     40GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
records
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