Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL307C
Length:
375
Number of sequences:
5887
Description:
YNL307C MCK1 SGDID:S000005251, Chr XIV from 57573-56446, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q3T0N5    366   MK13_BOVIN Mitogen-activated protein kinase 1...3166e-41     153     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92Q0U4L8    355   HOG1_PHANO Mitogen-activated protein kinase H...3227e-41     152     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93P24100    294   CDKA1_ARATH Cyclin-dependent kinase A-1 OS=Ar...3027e-41     151     32     52GO:0010005; C:cortical microtubule, transverse to long axis; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009574; C:preprophase band; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000910; P:cytokinesis; IMP:TAIR.::GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0008284; P:positive regulation of cell proliferation; IMP:TAIR.::GO:0040020; P:regulation of meiosis; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
94P42525    529   ERK1_DICDI Extracellular signal-regulated kin...3018e-41     155     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030587; P:sorocarp development; IMP:dictyBase.
95Q39027    368   MPK7_ARATH Mitogen-activated protein kinase 7...3279e-41     152     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0042542; P:response to hydrogen peroxide; IDA:TAIR.
96Q9WUI1    364   MK11_MOUSE Mitogen-activated protein kinase 1...3051e-40     152     31     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97A2QN07    396   MPKC_ASPNC Mitogen-activated protein kinase m...3231e-40     152     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
98Q9UV50    387   HOG1_DEBHA Mitogen-activated protein kinase H...3072e-40     152     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99Q40531    371   NTF6_TOBAC Mitogen-activated protein kinase h...3322e-40     152     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
100Q40884    384   MAPK_PETHY Mitogen-activated protein kinase h...3053e-40     151     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
101O08911    367   MK12_MOUSE Mitogen-activated protein kinase 1...3323e-40     151     31     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102O61443    365   MK14B_DROME Mitogen-activated protein kinase ...2973e-40     151     31     53GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; NAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IDA:UniProtKB.::GO:0006955; P:immune response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0045088; P:regulation of innate immune response; IDA:UniProtKB.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0009651; P:response to salt stress; IMP:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
103Q15759    364   MK11_HUMAN Mitogen-activated protein kinase 1...3003e-40     151     32     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
104Q92207    377   HOG1_CANAL Mitogen-activated protein kinase H...3404e-40     151     32     52GO:0005737; C:cytoplasm; IDA:CGD.::GO:0005634; C:nucleus; IDA:CGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:CGD.
GO:0071276; P:cellular response to cadmium ion; IMP:CGD.::GO:0034605; P:cellular response to heat; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0006973; P:intracellular accumulation of glycerol; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0046173; P:polyol biosynthetic process; IMP:CGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; IDA:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q9UBE8    527   NLK_HUMAN Serine/threonine-protein kinase NLK...3094e-40     153     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
106Q9WTY9    366   MK13_RAT Mitogen-activated protein kinase 13 ...3524e-40     150     32     51GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
107Q39025    376   MPK5_ARATH Mitogen-activated protein kinase 5...3124e-40     151     30     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
108E1BMN8    534   NLK_BOVIN Serine/threonine-protein kinase NLK...3094e-40     153     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
109A3LN91    385   HOG1_PICST Mitogen-activated protein kinase H...3414e-40     151     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110D3ZSZ3    527   NLK_RAT Serine/threonine-protein kinase NLK O...3094e-40     153     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
111O54949    527   NLK_MOUSE Serine/threonine-protein kinase NLK...3094e-40     153     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
112E2QWQ2    527   NLK_CANFA Serine/threonine-protein kinase NLK...3094e-40     153     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
113Q9U9Y8    634   NLK_CAEEL Serine/threonine kinase NLK OS=Caen...3284e-40     154     31     53GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001714; P:endodermal cell fate specification; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0042694; P:muscle cell fate specification; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0010085; P:polarity specification of proximal/distal axis; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:WormBase.
114Q10N20    369   MPK5_ORYSJ Mitogen-activated protein kinase 5...3674e-40     150     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006952; P:defense response; IEA:UniProtKB-KW.
115A2XFC8    369   MPK5_ORYSI Mitogen-activated protein kinase 5...3674e-40     150     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006952; P:defense response; IEA:UniProtKB-KW.
116O15264    365   MK13_HUMAN Mitogen-activated protein kinase 1...3345e-40     150     33     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q6CJA8    444   HOG1_KLULA Mitogen-activated protein kinase H...3345e-40     152     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118Q39021    370   MPK1_ARATH Mitogen-activated protein kinase 1...3036e-40     150     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; TAS:TAIR.
119Q6C4M9    386   HOG1_YARLI Mitogen-activated protein kinase H...3467e-40     150     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120O62618    366   MK14A_DROME Mitogen-activated protein kinase ...3037e-40     150     30     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; TAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0008348; P:negative regulation of antimicrobial humoral response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0080134; P:regulation of response to stress; IMP:FlyBase.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0006970; P:response to osmotic stress; IDA:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
121Q8NJT7    359   HOG1_HORWE Mitogen-activated protein kinase H...2967e-40     150     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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