rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
871 | Q9P1W9 | 311 | PIM2_HUMAN Serine/threonine-protein kinase pi... | 235 | 0.00000000000004 | 75.9 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007140; P:male meiosis; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB. | 872 | Q61084 | 626 | M3K3_MOUSE Mitogen-activated protein kinase k... | 297 | 0.00000000000004 | 77.4 | 28 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 873 | Q9Y2U5 | 619 | M3K2_HUMAN Mitogen-activated protein kinase k... | 227 | 0.00000000000004 | 77.4 | 30 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 874 | Q8RXG3 | 348 | M2K5_ARATH Mitogen-activated protein kinase k... | 229 | 0.00000000000004 | 76.3 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009814; P:defense response, incompatible interaction; IMP:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR. | 875 | P21137 | 404 | KAPC_CAEEL cAMP-dependent protein kinase cata... | 211 | 0.00000000000004 | 76.6 | 29 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:WormBase. | | | | | | | | | | GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase. | 876 | B4QK53 | 769 | PLK4_DROSI Serine/threonine-protein kinase PL... | 207 | 0.00000000000004 | 77.4 | 29 | 49 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 877 | P25321 | 351 | KAPCA_CRIGR cAMP-dependent protein kinase cat... | 211 | 0.00000000000004 | 76.3 | 28 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | | 878 | Q9C958 | 361 | SRK2B_ARATH Serine/threonine-protein kinase S... | 339 | 0.00000000000004 | 76.3 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009651; P:response to salt stress; IDA:TAIR. | 879 | Q8MYF1 | 456 | Y2070_DICDI Probable serine/threonine-protein... | 259 | 0.00000000000004 | 76.6 | 27 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 880 | Q6GPK9 | 1025 | TAOK2_XENLA Serine/threonine-protein kinase T... | 213 | 0.00000000000005 | 77.4 | 29 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB. | 881 | Q55EC7 | 960 | GEFX_DICDI RasGEF domain-containing serine/th... | 209 | 0.00000000000005 | 77.4 | 29 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 882 | P19525 | 551 | E2AK2_HUMAN Interferon-induced, double-strand... | 245 | 0.00000000000005 | 77 | 29 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; TAS:ProtInc.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; TAS:ProtInc.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; TAS:Reactome.::GO:0019054; P:modulation by virus of host cellular process; TAS:Reactome.::GO:0033689; P:negative regulation of osteoblast proliferation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0019058; P:viral infectious cycle; TAS:Reactome. | 883 | Q4P0K0 | 990 | ATG1_USTMA Serine/threonine-protein kinase AT... | 271 | 0.00000000000005 | 77.4 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 884 | P17612 | 351 | KAPCA_HUMAN cAMP-dependent protein kinase cat... | 211 | 0.00000000000005 | 76.3 | 28 | 48 | GO:0005952; C:cAMP-dependent protein kinase complex; NAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0045667; P:regulation of osteoblast differentiation; IDA:UniProtKB.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IDA:UniProtKB.::GO:0048240; P:sperm capacitation; ISS:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 885 | P00517 | 351 | KAPCA_BOVIN cAMP-dependent protein kinase cat... | 211 | 0.00000000000005 | 76.3 | 28 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001707; P:mesoderm formation; ISS:AgBase. | 886 | O64812 | 339 | SRK2J_ARATH Serine/threonine-protein kinase S... | 273 | 0.00000000000005 | 75.9 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 887 | Q8C1R0 | 372 | TSSK5_MOUSE Testis-specific serine/threonine-... | 320 | 0.00000000000005 | 76.3 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 888 | B6CZ17 | 551 | GRK7A_XENLA G protein-coupled receptor kinase... | 346 | 0.00000000000005 | 77 | 24 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 889 | Q54LH8 | 671 | Y6627_DICDI Probable serine/threonine-protein... | 214 | 0.00000000000005 | 77 | 26 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 890 | O12990 | 1153 | JAK1_DANRE Tyrosine-protein kinase JAK1 OS=Da... | 216 | 0.00000000000005 | 77.4 | 32 | 46 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 891 | Q8AYC9 | 476 | CHK1_CHICK Serine/threonine-protein kinase Ch... | 201 | 0.00000000000005 | 76.6 | 29 | 50 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB. | 892 | P22694 | 351 | KAPCB_HUMAN cAMP-dependent protein kinase cat... | 172 | 0.00000000000005 | 75.9 | 31 | 51 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 893 | Q5RAJ5 | 1315 | STK36_PONAB Serine/threonine-protein kinase 3... | 207 | 0.00000000000005 | 77.4 | 28 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB. | 894 | Q05655 | 676 | KPCD_HUMAN Protein kinase C delta type OS=Hom... | 341 | 0.00000000000005 | 77 | 26 | 43 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; TAS:BHF-UCL.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0090398; P:cellular senescence; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032091; P:negative regulation of protein binding; TAS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042119; P:neutrophil activation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000304; P:positive regulation of ceramide biosynthetic process; IMP:BHF-UCL.::GO:2000753; P:positive regulation of glucosylceramide catabolic process; IMP:BHF-UCL.::GO:1900163; P:positive regulation of phospholipid scramblase activity; IMP:UniProtKB.::GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.::GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.::GO:2000755; P:positive regulation of sphingomyelin catabolic process; IMP:BHF-UCL.::GO:0032930; P:positive regulation of superoxide anion generation; IMP:UniProtKB.::GO:0050821; P:protein stabilization; NAS:UniProtKB.::GO:0010469; P:regulation of receptor activity; TAS:BHF-UCL.::GO:0023021; P:termination of signal transduction; IMP:BHF-UCL. | 895 | Q5A649 | 834 | ATG1_CANAL Serine/threonine-protein kinase AT... | 282 | 0.00000000000005 | 77 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 896 | B4J3F1 | 762 | PLK4_DROGR Serine/threonine-protein kinase PL... | 293 | 0.00000000000005 | 77 | 26 | 44 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 897 | Q6DE87 | 474 | CHK1_XENLA Serine/threonine-protein kinase Ch... | 205 | 0.00000000000005 | 76.6 | 31 | 48 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB. | 898 | O97143 | 769 | PLK4_DROME Serine/threonine-protein kinase PL... | 207 | 0.00000000000006 | 77 | 29 | 49 | GO:0005814; C:centriole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase. | 899 | O75460 | 977 | ERN1_HUMAN Serine/threonine-protein kinase/en... | 314 | 0.00000000000006 | 77 | 28 | 46 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:InterPro.::GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 900 | Q69ZM6 | 1316 | STK36_MOUSE Serine/threonine-protein kinase 3... | 207 | 0.00000000000006 | 77 | 28 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB. | 901 | P25390 | 1331 | SSK22_YEAST Serine/threonine-protein kinase S... | 228 | 0.00000000000006 | 77 | 27 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD. |