Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL307C
Length:
375
Number of sequences:
5887
Description:
YNL307C MCK1 SGDID:S000005251, Chr XIV from 57573-56446, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661Q8WMV0    552   GRK7_BOVIN G protein-coupled receptor kinase ...2093e-17     86.7     28     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
662Q9WUT3    733   KS6A2_MOUSE Ribosomal protein S6 kinase alpha...2924e-17     86.7     28     43GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004711; F:ribosomal protein S6 kinase activity; IDA:MGI.
GO:0002035; P:brain renin-angiotensin system; IDA:MGI.::GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0060047; P:heart contraction; IDA:MGI.::GO:0007507; P:heart development; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0000089; P:mitotic metaphase; IDA:MGI.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0070613; P:regulation of protein processing; IDA:MGI.
663Q54QV3    1458   YAKA_DICDI Probable serine/threonine-protein ...2494e-17     87     28     47GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0007165; P:signal transduction; TAS:dictyBase.
664P22612    351   KAPCG_HUMAN cAMP-dependent protein kinase cat...2154e-17     85.1     31     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0008584; P:male gonad development; TAS:ProtInc.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome.
665Q8WP15    553   GRK7_PIG G protein-coupled receptor kinase 7 ...2135e-17     85.9     27     48GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
666P28829    659   BYR2_SCHPO Protein kinase byr2 OS=Schizosacch...2165e-17     86.3     33     50GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
667Q9Y7J6    550   PPK21_SCHPO Serine/threonine-protein kinase p...2436e-17     85.9     31     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0033205; P:cell cycle cytokinesis; TAS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
668Q7ZUQ3    492   STK3_DANRE Serine/threonine-protein kinase 3 ...2946e-17     85.5     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
669Q86SG6    692   NEK8_HUMAN Serine/threonine-protein kinase Ne...2326e-17     85.9     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
670Q86AD7    392   MYLKB_DICDI Probable myosin light chain kinas...3007e-17     84.7     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
671Q3U3Q1    472   ULK3_MOUSE Serine/threonine-protein kinase UL...2937e-17     85.5     26     46GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
672Q63184    513   E2AK2_RAT Interferon-induced, double-stranded...2477e-17     85.5     30     49GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033689; P:negative regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0043330; P:response to exogenous dsRNA; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IMP:RGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0033197; P:response to vitamin E; IPI:RGD.
673A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2107e-17     85.5     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
674Q12236    1081   PKH2_YEAST Serine/threonine-protein kinase PK...3218e-17     85.9     26     40GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
675Q75V57    361   SAPK9_ORYSJ Serine/threonine-protein kinase S...3469e-17     84.3     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
676Q751F5    581   SSN3_ASHGO Serine/threonine-protein kinase SS...2029e-17     85.1     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
677Q10407    1116   MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S...2201e-16     85.5     30     47GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase.
678Q04759    706   KPCT_HUMAN Protein kinase C theta type OS=Hom...3451e-16     85.1     27     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
679Q9N2L7    632   PLK2_CAEEL Serine/threonine-protein kinase pl...1661e-16     85.1     30     55GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; NAS:UniProtKB.::GO:0060631; P:regulation of meiosis I; IMP:WormBase.
680P49760    499   CLK2_HUMAN Dual specificity protein kinase CL...3281e-16     84.7     25     42GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
681Q9ESL4    802   MLTK_MOUSE Mitogen-activated protein kinase k...2361e-16     85.1     31     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:MGI.
GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
682Q940H6    362   SRK2E_ARATH Serine/threonine-protein kinase S...3191e-16     83.6     28     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0040007; P:growth; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0010359; P:regulation of anion channel activity; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0010118; P:stomatal movement; IMP:TAIR.::GO:0005985; P:sucrose metabolic process; IMP:TAIR.::GO:0019432; P:triglyceride biosynthetic process; IMP:TAIR.::GO:0006636; P:unsaturated fatty acid biosynthetic process; IMP:TAIR.
683Q12701    592   KSG1_SCHPO Serine/threonine-protein kinase ks...3201e-16     84.7     27     42GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
684Q925K9    273   TSSK6_MOUSE Testis-specific serine/threonine-...2071e-16     82.4     32     46
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0035092; P:sperm chromatin condensation; IMP:UniProtKB.
685P0CY24    1228   STE20_CANAL Serine/threonine-protein kinase C...2191e-16     85.1     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0000165; P:MAPK cascade; IGI:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IGI:CGD.
686Q91ZR4    698   NEK8_MOUSE Serine/threonine-protein kinase Ne...2321e-16     84.7     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0072372; C:primary cilium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
687C4YRB7    1224   STE20_CANAW Serine/threonine-protein kinase C...2191e-16     85.1     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
688P0CY23    1230   STE20_CANAX Serine/threonine-protein kinase C...2192e-16     85.1     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
689Q54PK9    908   PDPKB_DICDI 3-phosphoinositide-dependent prot...2122e-16     84.7     31     49
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
690Q4V3C8    486   PDPK2_ARATH 3-phosphoinositide-dependent prot...2502e-16     84.3     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
691Q03407    766   PKH1_YEAST Serine/threonine-protein kinase PK...2512e-16     84.3     29     45GO:0005829; C:cytosol; IDA:SGD.::GO:0032126; C:eisosome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
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