Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL307C
Length:
375
Number of sequences:
5887
Description:
YNL307C MCK1 SGDID:S000005251, Chr XIV from 57573-56446, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601Q8NE63    616   HIPK4_HUMAN Homeodomain-interacting protein k...2461e-19     94     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
602Q8IBS5    528   CDPK4_PLAF7 Calcium-dependent protein kinase ...3212e-19     93.2     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
603Q9XTF3    817   MBK2_CAEEL Dual specificity tyrosine-phosphor...3242e-19     94     28     47GO:0005938; C:cell cortex; IDA:WormBase.::GO:0005813; C:centrosome; IDA:WormBase.::GO:0005694; C:chromosome; IDA:WormBase.::GO:0043186; C:P granule; IDA:WormBase.
GO:0005524; F:ATP binding; ISS:WormBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; ISS:WormBase.
GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000281; P:cytokinesis after mitosis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:WormBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:WormBase.::GO:0045732; P:positive regulation of protein catabolic process; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0046777; P:protein autophosphorylation; ISS:WormBase.
604A8WJR8    815   MBK2_CAEBR Dual specificity tyrosine-phosphor...3242e-19     93.6     28     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
605Q9FZ36    651   M3K2_ARATH Mitogen-activated protein kinase k...3032e-19     93.2     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0000910; P:cytokinesis; IGI:TAIR.
606P51568    400   AFC3_ARATH Serine/threonine-protein kinase AF...3353e-19     91.7     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
607Q7RJG2    528   CDPK4_PLAYO Calcium-dependent protein kinase ...3573e-19     92.8     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
608Q5UNT4    539   YL670_MIMIV Putative serine/threonine-protein...3133e-19     92.8     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
609Q9VP22    1157   CDK12_DROME Cyclin-dependent kinase 12 OS=Dro...2353e-19     93.2     30     49GO:0000228; C:nuclear chromosome; IDA:UniProtKB.::GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005703; C:polytene chromosome puff; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:UniProtKB.
610Q55GU0    916   Y9955_DICDI Probable serine/threonine-protein...2344e-19     92.8     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
611O74304    1436   WIN1_SCHPO MAP kinase kinase kinase win1 OS=S...3584e-19     92.8     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
612Q6A1A2    396   PDPK2_HUMAN Putative 3-phosphoinositide-depen...3104e-19     91.3     29     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
613Q9HAZ1    481   CLK4_HUMAN Dual specificity protein kinase CL...3315e-19     91.7     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
614P0C8M8    626   CCR1_MAIZE Probable serine/threonine-protein ...3055e-19     92     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
615Q9WTR2    1291   M3K6_MOUSE Mitogen-activated protein kinase k...2067e-19     92     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
616O95382    1288   M3K6_HUMAN Mitogen-activated protein kinase k...2077e-19     92     33     49
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
617O55173    559   PDPK1_RAT 3-phosphoinositide-dependent protei...3108e-19     91.3     28     43GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.
GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
618P62345    528   CDPK4_PLABA Calcium-dependent protein kinase ...3578e-19     91.3     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
619O15865    513   CDPK2_PLAFK Calcium-dependent protein kinase ...3049e-19     91.3     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
620Q8ICR0    509   CDPK2_PLAF7 Calcium-dependent protein kinase ...3049e-19     91.3     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:GeneDB_Pfalciparum.
621Q54UA9    932   CLKA_DICDI Probable serine/threonine-protein ...3481e-18     91.3     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
622O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...3101e-18     90.9     29     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
623O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...2471e-18     90.5     30     49GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
624P22216    821   RAD53_YEAST Serine/threonine-protein kinase R...2171e-18     91.3     30     52GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.
625Q9SPK4    284   PPCK1_ARATH Phosphoenolpyruvate carboxylase k...2691e-18     88.2     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046898; P:response to cycloheximide; IDA:UniProtKB.::GO:0009416; P:response to light stimulus; IDA:UniProtKB.
626Q9Z2G7    548   GRK7_SPETR G protein-coupled receptor kinase ...2082e-18     90.5     28     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
627Q8IYT8    1036   ULK2_HUMAN Serine/threonine-protein kinase UL...2252e-18     90.9     33     48GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
628P07934    388   PHKG1_MOUSE Phosphorylase b kinase gamma cata...2872e-18     89.4     27     46GO:0005964; C:phosphorylase kinase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
629Q54PX0    496   Y4251_DICDI Probable serine/threonine-protein...2472e-18     90.1     31     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
630P13286    388   PHKG1_RAT Phosphorylase b kinase gamma cataly...2872e-18     89     27     46GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
631Q66KH9    416   CDK8_XENLA Cyclin-dependent kinase 8 OS=Xenop...1972e-18     89.4     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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