Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL305C
Length:
297
Number of sequences:
5887
Description:
YNL305C BXI1 SGDID:S000005249, Chr XIV from 59791-58898, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in apoptosis; variously described as containing a BCL-2 homology (BH3) domain or as a member of the BAX inhibitor family; reported to promote apoptosis under some conditions and to inhibit it in others; localizes to ER and vacuole; may link the unfolded protein response to apoptosis via regulation of calcium-mediated signaling; translocates to mitochondria under apoptosis-inducing conditions in a process involving Mir1p and Cor1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P48558    297   BXI1_YEAST Bax inhibitor 1 OS=Saccharomyces c...2970     606     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000324; C:fungal-type vacuole; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IMP:SGD.::GO:0019722; P:calcium-mediated signaling; IMP:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.
2Q9DA39    238   LFG4_MOUSE Protein lifeguard 4 OS=Mus musculu...2841e-18     86.7     30     43GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0050848; P:regulation of calcium-mediated signaling; ISS:UniProtKB.
3Q969X1    311   LFG3_HUMAN Protein lifeguard 3 OS=Homo sapien...2537e-17     82.4     24     48GO:0010008; C:endosome membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.
4Q8BJZ3    309   LFG3_MOUSE Protein lifeguard 3 OS=Mus musculu...2537e-17     82.4     25     50GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.
GO:0050848; P:regulation of calcium-mediated signaling; ISS:UniProtKB.
5O74888    266   BXI1_SCHPO Bax inhibitor 1 OS=Schizosaccharom...2993e-16     80.1     24     40GO:0005783; C:endoplasmic reticulum; ISS:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; ISS:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.
GO:0006915; P:apoptotic process; ISS:PomBase.::GO:0019722; P:calcium-mediated signaling; ISS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.
6Q7Z429    371   LFG1_HUMAN Protein lifeguard 1 OS=Homo sapien...3040.000000000000006     77.4     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
7Q32L53    366   LFG1_BOVIN Protein lifeguard 1 OS=Bos taurus ...3040.000000000000007     77.4     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
8Q6P6R0    348   LFG1_RAT Protein lifeguard 1 OS=Rattus norveg...2540.00000000000002     75.9     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005261; F:cation channel activity; NAS:RGD.
9Q9ESF4    345   LFG1_MOUSE Protein lifeguard 1 OS=Mus musculu...2890.00000000000003     75.5     25     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
10Q9HC24    238   LFG4_HUMAN Protein lifeguard 4 OS=Homo sapien...3000.0000000000001     72     29     42GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0050848; P:regulation of calcium-mediated signaling; IDA:UniProtKB.
11Q5R4I4    316   LFG2_PONAB Protein lifeguard 2 OS=Pongo abeli...2990.000000000001     70.9     25     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0021681; P:cerebellar granular layer development; ISS:UniProtKB.::GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
12Q9BWQ8    316   LFG2_HUMAN Protein lifeguard 2 OS=Homo sapien...2990.000000000001     70.5     24     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0021681; P:cerebellar granular layer development; ISS:UniProtKB.::GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; IMP:UniProtKB.
13Q1LZ71    316   LFG2_BOVIN Protein lifeguard 2 OS=Bos taurus ...2990.000000000004     68.9     24     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0021681; P:cerebellar granular layer development; ISS:UniProtKB.::GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
14O88407    316   LFG2_RAT Protein lifeguard 2 OS=Rattus norveg...2540.000000000008     68.2     24     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0021681; P:cerebellar granular layer development; ISS:UniProtKB.::GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
15Q8K097    317   LFG2_MOUSE Protein lifeguard 2 OS=Mus musculu...2540.000000000008     68.2     25     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0021681; P:cerebellar granular layer development; IMP:UniProtKB.::GO:0021702; P:cerebellar Purkinje cell differentiation; IMP:UniProtKB.::GO:0043523; P:regulation of neuron apoptotic process; IMP:UniProtKB.
16O51489    232   Y539_BORBU Uncharacterized protein BB_0539 OS...2630.00000002     57.4     24     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
17Q94A20    256   BI1L_ARATH BI1-like protein OS=Arabidopsis th...1600.0000004     53.9     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
18Q11080    276   TMBI4_CAEEL Transmembrane BAX inhibitor motif...1480.0000005     53.5     28     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
19Q9PIQ8    231   Y236_CAMJE Uncharacterized protein Cj0236c OS...1360.000007     50.1     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
20Q9ZKT1    230   Y920_HELPJ Uncharacterized protein jhp_0854 O...1220.0006     43.9     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
21O25578    230   Y920_HELPY Uncharacterized protein HP_0920 OS...1220.0008     43.5     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
22Q9LD45    247   BI1_ARATH Bax inhibitor 1 OS=Arabidopsis thal...1590.002     42.7     28     49GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006983; P:ER overload response; IMP:TAIR.::GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0000038; P:very long-chain fatty acid metabolic process; IMP:TAIR.
23Q9A1B9    229   Y358_STRP1 Uncharacterized membrane protein S...1940.041     38.5     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
24Q8P2D4    229   Y408_STRP8 Uncharacterized membrane protein s...1940.059     37.7     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
25Q5XDQ1    229   Y327_STRP6 Uncharacterized membrane protein M...1940.059     37.7     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
26P0DA11    229   Y260_STRPQ Uncharacterized membrane protein S...1940.081     37.4     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
27P0DA10    229   Y260_STRP3 Uncharacterized membrane protein S...1940.081     37.4     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
28O31539    214   YETJ_BACSU Uncharacterized protein YetJ OS=Ba...590.17     36.6     34     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
29Q9MBD8    249   BI1_ORYSJ Bax inhibitor 1 OS=Oryza sativa sub...770.37     35.4     31     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IGI:Gramene.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
30Q9IA79    237   BI1_PAROL Probable Bax inhibitor 1 OS=Paralic...2710.37     35.4     22     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
31Q9ZE15    236   Y147_RICPR Uncharacterized protein RP147 OS=R...610.71     34.7     36     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
records
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