rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | B0WAU8 | 761 | PLK4_CULQU Serine/threonine-protein kinase PL... | 225 | 1e-22 | 107 | 29 | 48 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 512 | P53670 | 638 | LIMK2_RAT LIM domain kinase 2 OS=Rattus norve... | 195 | 1e-22 | 107 | 29 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007286; P:spermatid development; TAS:RGD. | 513 | P54744 | 622 | PKNB_MYCLE Serine/threonine-protein kinase pk... | 186 | 1e-22 | 107 | 30 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 514 | Q4KTY1 | 415 | KPSH1_PINFU Serine/threonine-protein kinase H... | 226 | 1e-22 | 105 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 515 | Q15139 | 912 | KPCD1_HUMAN Serine/threonine-protein kinase D... | 190 | 1e-22 | 107 | 35 | 59 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IMP:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0045806; P:negative regulation of endocytosis; TAS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:BHF-UCL.::GO:2001044; P:regulation of integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 516 | Q09137 | 552 | AAPK2_RAT 5'-AMP-activated protein kinase cat... | 244 | 1e-22 | 106 | 30 | 51 | GO:0031588; C:AMP-activated protein kinase complex; IDA:RGD.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030674; F:protein binding, bridging; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 517 | O42632 | 1174 | KPC1_COCHE Protein kinase C-like OS=Cochliobo... | 227 | 1e-22 | 108 | 27 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 518 | P13286 | 388 | PHKG1_RAT Phosphorylase b kinase gamma cataly... | 234 | 1e-22 | 104 | 31 | 51 | GO:0005964; C:phosphorylase kinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IDA:RGD.::GO:0004689; F:phosphorylase kinase activity; IDA:RGD. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:InterPro. | 519 | Q9NJU9 | 562 | CDPK3_PLAF7 Calcium-dependent protein kinase ... | 221 | 1e-22 | 106 | 32 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 520 | Q03042 | 768 | KGP1_DROME cGMP-dependent protein kinase, iso... | 221 | 1e-22 | 107 | 31 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:FlyBase. | | | | | | | | | | | 521 | Q9NRH2 | 765 | SNRK_HUMAN SNF-related serine/threonine-prote... | 241 | 1e-22 | 107 | 31 | 51 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB. | 522 | Q9Y6R4 | 1608 | M3K4_HUMAN Mitogen-activated protein kinase k... | 290 | 1e-22 | 108 | 27 | 47 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB. | 523 | A7TIZ4 | 994 | ATG1_VANPO Serine/threonine-protein kinase at... | 301 | 1e-22 | 107 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 524 | Q5R9Z7 | 970 | PLK4_PONAB Serine/threonine-protein kinase PL... | 297 | 1e-22 | 107 | 26 | 44 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB. | 525 | Q91YA2 | 424 | KPSH1_MOUSE Serine/threonine-protein kinase H... | 236 | 1e-22 | 104 | 29 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 526 | Q5XIT0 | 507 | CDKL2_RAT Cyclin-dependent kinase-like 2 OS=R... | 273 | 1e-22 | 105 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 527 | Q5RDH5 | 554 | AAPK1_PONAB 5'-AMP-activated protein kinase c... | 247 | 2e-22 | 106 | 31 | 52 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 528 | Q5EG47 | 559 | AAPK1_MOUSE 5'-AMP-activated protein kinase c... | 247 | 2e-22 | 106 | 31 | 52 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0019395; P:fatty acid oxidation; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; IDA:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 529 | Q9M077 | 294 | AUR1_ARATH Serine/threonine-protein kinase Au... | 223 | 2e-22 | 103 | 30 | 49 | GO:0009504; C:cell plate; IDA:TAIR.::GO:0005874; C:microtubule; IDA:TAIR.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:TAIR. | | | | | | | | | | | 530 | Q95ZQ4 | 626 | AAPK2_CAEEL 5'-AMP-activated protein kinase c... | 255 | 2e-22 | 106 | 31 | 49 | GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:WormBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 531 | Q13131 | 559 | AAPK1_HUMAN 5'-AMP-activated protein kinase c... | 247 | 2e-22 | 106 | 31 | 52 | GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; NAS:UniProtKB.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046318; P:negative regulation of glucosylceramide biosynthetic process; NAS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045542; P:positive regulation of cholesterol biosynthetic process; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; NAS:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 532 | Q9HC98 | 313 | NEK6_HUMAN Serine/threonine-protein kinase Ne... | 268 | 2e-22 | 103 | 27 | 49 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IDA:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB. | 533 | Q2LZZ7 | 458 | TRC_DROPS Serine/threonine-protein kinase tri... | 280 | 2e-22 | 105 | 27 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0050773; P:regulation of dendrite development; ISS:UniProtKB. | 534 | P54645 | 559 | AAPK1_RAT 5'-AMP-activated protein kinase cat... | 247 | 2e-22 | 106 | 31 | 52 | GO:0031588; C:AMP-activated protein kinase complex; IDA:UniProtKB.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042557; F:eukaryotic elongation factor-2 kinase activator activity; NAS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0071361; P:cellular response to ethanol; IEP:RGD.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; NAS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:RGD.::GO:0046321; P:positive regulation of fatty acid oxidation; NAS:UniProtKB.::GO:0045722; P:positive regulation of gluconeogenesis; NAS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; NAS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060627; P:regulation of vesicle-mediated transport; IMP:RGD.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 535 | P00518 | 387 | PHKG1_RABIT Phosphorylase b kinase gamma cata... | 234 | 2e-22 | 103 | 31 | 52 | GO:0005964; C:phosphorylase kinase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC. | | | | | | | | | | GO:0005978; P:glycogen biosynthetic process; IEA:InterPro. | 536 | Q16W24 | 769 | PLK4_AEDAE Serine/threonine-protein kinase PL... | 290 | 2e-22 | 107 | 27 | 46 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 537 | Q501V0 | 422 | KPSH1_DANRE Serine/threonine-protein kinase H... | 238 | 2e-22 | 104 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 538 | Q9WTQ1 | 918 | KPCD1_RAT Serine/threonine-protein kinase D1 ... | 190 | 2e-22 | 107 | 35 | 59 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB. | 539 | P53599 | 1579 | SSK2_YEAST MAP kinase kinase kinase SSK2 OS=S... | 273 | 2e-22 | 107 | 29 | 47 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:SGD.::GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.::GO:0007234; P:osmosensory signaling pathway via two-component system; IPI:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD. | 540 | Q96QS6 | 385 | KPSH2_HUMAN Serine/threonine-protein kinase H... | 238 | 2e-22 | 103 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 541 | Q54IF2 | 641 | Y0670_DICDI Probable serine/threonine-protein... | 297 | 2e-22 | 106 | 27 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | |