Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL298W
Length:
842
Number of sequences:
5887
Description:
YNL298W CLA4 SGDID:S000005242, Chr XIV from 68915-71443, Genome Release 64-1-1, Verified ORF, "Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121B7ZR30    950   STK10_XENLA Serine/threonine-protein kinase 1...3106e-38     156     34     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
122Q6NU21    1001   TAO1A_XENLA Serine/threonine-protein kinase T...2907e-38     156     36     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
123Q5R4F3    898   TAOK3_PONAB Serine/threonine-protein kinase T...2902e-37     155     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.
124P23561    717   STE11_YEAST Serine/threonine-protein kinase S...2982e-37     153     33     53GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:SGD.::GO:0032093; F:SAM domain binding; IDA:SGD.
GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0010525; P:regulation of transposition, RNA-mediated; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.
125A7A1P0    717   STE11_YEAS7 Serine/threonine-protein kinase S...2982e-37     153     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
126Q54XL6    574   FRAY1_DICDI Serine/threonine-protein kinase f...3094e-37     151     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
127Q10407    1116   MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S...3011e-36     152     32     51GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase.
128Q7SY52    974   STK10_DANRE Serine/threonine-protein kinase 1...3071e-36     152     32     49GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
129Q54XJ4    1495   Y8901_DICDI Probable serine/threonine-protein...2183e-36     152     38     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
130B5VNQ3    717   STE11_YEAS6 Serine/threonine-protein kinase S...2987e-36     149     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
131Q54PX0    496   Y4251_DICDI Probable serine/threonine-protein...2912e-35     145     32     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
132Q54R82    942   MKKA_DICDI Mitogen-activated protein kinase k...2812e-35     148     36     51GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
133Q99759    626   M3K3_HUMAN Mitogen-activated protein kinase k...2893e-35     146     35     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.
134O14427    971   CLA4_CANAX Serine/threonine-protein kinase CL...2784e-35     147     36     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
135Q61084    626   M3K3_MOUSE Mitogen-activated protein kinase k...2909e-35     144     35     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
136P41892    1062   CDC7_SCHPO Cell division control protein 7 OS...2771e-34     146     34     52GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
137O22042    651   M3K3_ARATH Mitogen-activated protein kinase k...2951e-34     144     32     50GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.
138O22040    666   ANP1_ARATH Mitogen-activated protein kinase k...3002e-34     144     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
139P46549    982   SULU_CAEEL Serine/threonine-protein kinase SU...2993e-34     145     34     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
140Q39008    608   M3K1_ARATH Mitogen-activated protein kinase k...2824e-34     142     33     52GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0019900; F:kinase binding; IPI:TAIR.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IDA:TAIR.
141Q54B33    926   PAKE_DICDI Serine/threonine-protein kinase pa...2977e-34     144     32     49
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IMP:dictyBase.
142Q56UN5    1328   YSK4_HUMAN SPS1/STE20-related protein kinase ...2908e-34     144     31     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
143Q9R011    647   PLK3_RAT Serine/threonine-protein kinase PLK3...2434e-33     140     34     53GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071779; P:G1/S transition checkpoint; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; NAS:RGD.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; ISS:UniProtKB.
144Q60806    631   PLK3_MOUSE Serine/threonine-protein kinase PL...2434e-33     139     34     53GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071779; P:G1/S transition checkpoint; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; ISS:UniProtKB.
145Q01389    1478   BCK1_YEAST Serine/threonine-protein kinase BC...2889e-33     140     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.::GO:0007584; P:response to nutrient; IMP:SGD.
146Q9H4B4    646   PLK3_HUMAN Serine/threonine-protein kinase PL...2432e-32     137     33     53GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007113; P:endomitotic cell cycle; TAS:UniProtKB.::GO:0071779; P:G1/S transition checkpoint; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0090166; P:Golgi disassembly; IDA:UniProtKB.::GO:0071780; P:mitotic cell cycle G2/M transition checkpoint; TAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; IDA:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB.::GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; IMP:UniProtKB.
147Q9Y2U5    619   M3K2_HUMAN Mitogen-activated protein kinase k...2854e-32     136     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
148Q9FZ36    651   M3K2_ARATH Mitogen-activated protein kinase k...3346e-32     136     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0000910; P:cytokinesis; IGI:TAIR.
149Q61083    619   M3K2_MOUSE Mitogen-activated protein kinase k...2852e-31     134     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
150Q5QN75    355   M2K1_ORYSJ Mitogen-activated protein kinase k...3174e-31     130     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
151Q9SZ67    1895   WRK19_ARATH Probable WRKY transcription facto...2945e-31     135     33     50GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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