Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL280C
Length:
438
Number of sequences:
5887
Description:
YNL280C ERG24 SGDID:S000005224, Chr XIV from 110411-109095, Genome Release 64-1-1, reverse complement, Verified ORF, "C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32462    438   ERG24_YEAST Delta(14)-sterol reductase OS=Sac...4380     894     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IDA:SGD.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.
2Q09195    424   ERG24_SCHPO Delta(14)-sterol reductase OS=Sch...4452e-120     364     45     63GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
3P78575    430   ERG24_ASCIM Delta(14)-sterol reductase OS=Asc...4331e-100     313     41     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
4Q01447    485   ERG24_FUSSO Delta(14)-sterol reductase OS=Fus...3951e-98     310     42     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
5Q3U9G9    626   LBR_MOUSE Lamin-B receptor OS=Mus musculus (M...4471e-96     309     41     57GO:0005637; C:nuclear inner membrane; TAS:MGI.::GO:0005652; C:nuclear lamina; TAS:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
6P38670    490   ERG24_NEUCR Delta(14)-sterol reductase OS=125...4931e-96     305     36     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
7O08984    620   LBR_RAT Lamin-B receptor OS=Rattus norvegicus...4482e-94     303     40     57GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:RGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
8O13597    512   ERG24_SEPLY Delta(14)-sterol reductase OS=Sep...4989e-93     296     38     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
9Q5R7H4    615   LBR_PONAB Lamin-B receptor OS=Pongo abelii (S...4413e-91     295     40     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
10Q14739    615   LBR_HUMAN Lamin-B receptor OS=Homo sapiens (H...4426e-89     289     40     55GO:0005639; C:integral to nuclear inner membrane; TAS:ProtInc.
GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005521; F:lamin binding; TAS:ProtInc.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
11P23913    637   LBR_CHICK Lamin-B receptor OS=Gallus gallus (...4371e-88     288     40     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
12O76062    418   ERG24_HUMAN Delta(14)-sterol reductase OS=Hom...3572e-87     279     44     60GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
13Q71KT5    418   ERG24_MOUSE Delta(14)-sterol reductase OS=Mus...4433e-87     279     40     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
14Q8WMV1    418   ERG24_BOVIN Delta(14)-sterol reductase OS=Bos...3575e-84     270     43     58GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050613; F:delta14-sterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
15Q54PP1    462   ERG24_DICDI Delta(14)-sterol reductase OS=Dic...4436e-73     243     34     55GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; ISS:dictyBase.
GO:0006696; P:ergosterol biosynthetic process; IC:dictyBase.
16Q9LDR4    369   ERG24_ARATH Delta(14)-sterol reductase OS=Ara...3725e-60     206     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050613; F:delta14-sterol reductase activity; IMP:TAIR.
GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
17Q7ZXH1    473   DHCR7_XENLA 7-dehydrocholesterol reductase OS...3613e-54     193     34     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
18Q6P4M0    473   DHCR7_XENTR 7-dehydrocholesterol reductase OS...3886e-54     192     32     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
19Q5UQI4    447   DHCR7_MIMIV Probable 7-dehydrocholesterol red...2583e-52     187     40     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
20P36209    453   STS1_SCHPO Delta(24(24(1)))-sterol reductase ...4654e-52     187     31     47GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000246; F:delta24(24-1) sterol reductase activity; ISS:PomBase.
GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0071473; P:cellular response to cation stress; IMP:PomBase.::GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0090002; P:establishment of protein localization in plasma membrane; IMP:PomBase.::GO:0071210; P:protein insertion into membrane raft; IMP:PomBase.::GO:0042493; P:response to drug; IMP:PomBase.
21Q7SXF1    478   DHCR7_DANRE 7-dehydrocholesterol reductase OS...3942e-51     186     31     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
22Q9UBM7    475   DHCR7_HUMAN 7-dehydrocholesterol reductase OS...4101e-48     178     31     48GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005640; C:nuclear outer membrane; IDA:UniProtKB.
GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0006695; P:cholesterol biosynthetic process; IMP:UniProtKB.
23Q5E9J5    475   DHCR7_BOVIN 7-dehydrocholesterol reductase OS...3902e-48     177     32     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
24O88455    471   DHCR7_MOUSE 7-dehydrocholesterol reductase OS...2643e-47     174     39     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:MGI.
GO:0001568; P:blood vessel development; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0030324; P:lung development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.
25Q9Z2Z8    471   DHCR7_RAT 7-dehydrocholesterol reductase OS=R...2644e-47     174     38     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
GO:0047598; F:7-dehydrocholesterol reductase activity; IMP:RGD.
GO:0006695; P:cholesterol biosynthetic process; IDA:RGD.::GO:0045540; P:regulation of cholesterol biosynthetic process; IDA:RGD.
26P25340    473   ERG4_YEAST Delta(24(24(1)))-sterol reductase ...4762e-44     166     30     47GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000246; F:delta24(24-1) sterol reductase activity; IDA:SGD.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.
27Q9LDU6    432   ST7R_ARATH 7-dehydrocholesterol reductase OS=...3711e-42     160     31     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0047598; F:7-dehydrocholesterol reductase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0009918; F:sterol delta7 reductase activity; IMP:TAIR.
GO:0016132; P:brassinosteroid biosynthetic process; IMP:TAIR.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
28Q8MLV1    741   LBR_DROME Lamin-B receptor OS=Drosophila mela...3650.0000000000008     74.3     23     44GO:0005639; C:integral to nuclear inner membrane; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005521; F:lamin binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006997; P:nucleus organization; IC:UniProtKB.
29Q64V41    322   HTPX_BACFR Protease HtpX homolog OS=Bacteroid...1180.87     35.4     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
30Q5LE03    322   HTPX_BACFN Protease HtpX homolog OS=Bacteroid...1181.1     35     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
records
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