rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 271 | 5e-30 | 123 | 31 | 49 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 122 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 264 | 7e-30 | 122 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 123 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 264 | 7e-30 | 122 | 32 | 50 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 124 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 264 | 8e-30 | 122 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 125 | Q4L8G4 | 318 | Y752_STAHJ Putative 2-hydroxyacid dehydrogena... | 246 | 1e-29 | 120 | 32 | 55 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 126 | P26298 | 332 | LDHD_LACPE D-lactate dehydrogenase OS=Lactoba... | 257 | 4e-29 | 119 | 31 | 49 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 127 | P17584 | 333 | DHD2_LACPA D-2-hydroxyisocaproate dehydrogena... | 258 | 8e-29 | 118 | 30 | 49 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 128 | P73821 | 554 | SERA_SYNY3 D-3-phosphoglycerate dehydrogenase... | 241 | 1e-28 | 119 | 29 | 49 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 129 | O13437 | 364 | FDH_CANBO Formate dehydrogenase OS=Candida bo... | 204 | 3e-28 | 117 | 37 | 55 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008863; F:formate dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0042426; P:choline catabolic process; IMP:UniProtKB.::GO:0042183; P:formate catabolic process; IDA:UniProtKB.::GO:0015946; P:methanol oxidation; IMP:UniProtKB.::GO:0030416; P:methylamine metabolic process; IMP:UniProtKB.::GO:0006735; P:NADH regeneration; IDA:UniProtKB. | 130 | P52643 | 329 | LDHD_ECOLI D-lactate dehydrogenase OS=Escheri... | 248 | 3e-28 | 116 | 30 | 50 | GO:0005625; C:soluble fraction; IDA:EcoCyc. | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IDA:EcoCyc.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0019664; P:glucose catabolic process to mixed acids; IDA:EcoCyc.::GO:0009408; P:response to heat; IEP:EcoliWiki. | 131 | O46036 | 476 | CTBP_DROME C-terminal-binding protein OS=Dros... | 275 | 5e-28 | 117 | 32 | 51 | GO:0005634; C:nucleus; IDA:FlyBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:FlyBase.::GO:0070491; F:repressing transcription factor binding; IPI:FlyBase.::GO:0003713; F:transcription coactivator activity; IDA:FlyBase.::GO:0003714; F:transcription corepressor activity; IDA:FlyBase. | | | | | | | | | | GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IGI:FlyBase. | 132 | Q03134 | 365 | FDH_EMENI Probable formate dehydrogenase OS=1... | 245 | 2e-27 | 114 | 33 | 52 | | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 133 | C8ZHD6 | 376 | FDH2_YEAS8 Formate dehydrogenase 2 OS=(Baker'... | 215 | 2e-27 | 114 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 134 | A6ZN46 | 376 | FDH2_YEAS7 Formate dehydrogenase 2 OS=Sacchar... | 215 | 2e-27 | 114 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 135 | Q08911 | 376 | FDH1_YEAST Formate dehydrogenase 1 OS=Sacchar... | 215 | 2e-27 | 114 | 33 | 53 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IGI:SGD.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0042183; P:formate catabolic process; IGI:SGD.::GO:0006735; P:NADH regeneration; TAS:SGD. | 136 | Q59642 | 331 | LDHD_PEDAC D-lactate dehydrogenase OS=Pedioco... | 258 | 3e-27 | 113 | 27 | 49 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 137 | O83080 | 331 | LDHD_TREPA D-lactate dehydrogenase OS=Trepone... | 256 | 4e-27 | 113 | 33 | 49 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 138 | Q05709 | 322 | VANH_ENTFC D-specific alpha-keto acid dehydro... | 276 | 2e-26 | 111 | 31 | 49 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 139 | O04130 | 624 | SERA_ARATH D-3-phosphoglycerate dehydrogenase... | 242 | 3e-26 | 114 | 31 | 48 | GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 140 | Q59516 | 314 | DHGY_METEA Glycerate dehydrogenase OS=Methylo... | 251 | 3e-26 | 110 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 141 | P45250 | 315 | Y1556_HAEIN Putative 2-hydroxyacid dehydrogen... | 256 | 7e-26 | 109 | 33 | 50 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 142 | Q47748 | 323 | VANH_ENTFA D-specific alpha-keto acid dehydro... | 249 | 2e-25 | 108 | 31 | 47 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW. | 143 | P13443 | 382 | DHGY_CUCSA Glycerate dehydrogenase OS=Cucumis... | 254 | 2e-25 | 108 | 31 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0009854; P:oxidative photosynthetic carbon pathway; IEA:UniProtKB-KW. | 144 | Q07103 | 375 | FDH_NEUCR Formate dehydrogenase OS=1257 / FGS... | 236 | 2e-25 | 108 | 35 | 54 | | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 145 | P51011 | 331 | LDHD_LEUMC D-lactate dehydrogenase OS=Leucono... | 241 | 7e-25 | 106 | 32 | 48 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 146 | P33677 | 362 | FDH_PICAN Formate dehydrogenase OS=Pichia ang... | 204 | 8e-25 | 107 | 34 | 53 | | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 147 | P43885 | 410 | SERA_HAEIN D-3-phosphoglycerate dehydrogenase... | 245 | 9e-25 | 107 | 30 | 51 | GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:InterPro. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW. | 148 | Q8D2P6 | 378 | PDXB_WIGBR Erythronate-4-phosphate dehydrogen... | 278 | 1e-24 | 106 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW. | 149 | Q54UF7 | 340 | LDHD_DICDI Putative D-lactate dehydrogenase O... | 195 | 1e-24 | 106 | 33 | 56 | GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; ISS:dictyBase.::GO:0051287; F:NAD binding; ISS:dictyBase. | | | | | | | | | | GO:0019652; P:lactate fermentation to propionate and acetate; ISS:dictyBase. | 150 | P33160 | 401 | FDH_PSESR Formate dehydrogenase OS=Pseudomona... | 198 | 3e-24 | 105 | 35 | 52 | | | | | | | | | | | GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 151 | P30799 | 331 | DDH_ZYMMO 2-hydroxyacid dehydrogenase homolog... | 195 | 4e-24 | 104 | 33 | 54 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | |