Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL273W
Length:
1238
Number of sequences:
5887
Description:
YNL273W TOF1 SGDID:S000005217, Chr XIV from 122883-126599, Genome Release 64-1-1, Verified ORF, "Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53840    1238   TOF1_YEAST Topoisomerase 1-associated factor ...12380     2540     100     100GO:0031298; C:replication fork protection complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006281; P:DNA repair; IMP:SGD.::GO:0000076; P:DNA replication checkpoint; IPI:SGD.::GO:0043570; P:maintenance of DNA repeat elements; IMP:SGD.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD.::GO:0043111; P:replication fork arrest; IMP:SGD.::GO:0048478; P:replication fork protection; IMP:SGD.
2Q6FNX7    1176   TOF1_CANGA Topoisomerase 1-associated factor ...11640     1271     55     73GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
3Q6CUU2    1162   TOF1_KLULA Topoisomerase 1-associated factor ...11100     880     43     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
4Q752A3    1265   TOF1_ASHGO Topoisomerase 1-associated factor ...11870     862     40     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
5Q6BPI8    1299   TOF1_DEBHA Topoisomerase 1-associated factor ...12971e-141     469     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
6Q59NW5    1263   TOF1_CANAL Topoisomerase 1-associated factor ...10212e-132     443     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
7A5DJ85    1216   TOF1_PICGU Topoisomerase 1-associated factor ...11585e-126     425     30     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
8A3LR41    1256   TOF1_PICST Topoisomerase 1-associated factor ...12173e-124     420     30     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
9A5E2H7    1175   TOF1_LODEL Topoisomerase 1-associated factor ...8193e-117     399     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
10Q2PIU8    1166   TOF1_ASPOR Topoisomerase 1-associated factor ...9705e-89     318     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
11Q4W9M7    1176   TOF1_ASPFU Topoisomerase 1-associated factor ...9546e-88     315     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
12A1D9I5    1177   TOF1_NEOFI Topoisomerase 1-associated factor ...9422e-87     313     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
13A1C928    1178   TOF1_ASPCL Topoisomerase 1-associated factor ...8979e-86     308     27     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
14Q1DM35    1171   TOF1_COCIM Topoisomerase 1-associated factor ...9982e-85     307     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
15A2R2E3    1169   TOF1_ASPNC Topoisomerase 1-associated factor ...9413e-85     306     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
16Q0UJF3    1177   TOF1_PHANO Topoisomerase 1-associated factor ...9611e-83     301     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
17Q0CU99    1147   TOF1_ASPTN Topoisomerase 1-associated factor ...10032e-83     300     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
18Q5AXH3    1167   TOF1_EMENI Topoisomerase 1-associated factor ...9952e-82     297     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
19Q7S2A9    1235   TOF1_NEUCR Topoisomerase 1-associated factor ...10344e-77     282     26     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
20Q9UUM2    971   SWI1_SCHPO Mating-type switching protein swi1...9692e-73     268     25     46GO:0031298; C:replication fork protection complex; TAS:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071515; P:genetic imprinting at mating-type locus; IMP:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IGI:PomBase.::GO:0045950; P:negative regulation of mitotic recombination; IDA:PomBase.::GO:0043111; P:replication fork arrest; IDA:PomBase.::GO:0048478; P:replication fork protection; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
21A4R4R3    1214   TOF1_MAGO7 Topoisomerase 1-associated factor ...9224e-73     270     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
22Q2HBI0    1251   TOF1_CHAGB Topoisomerase 1-associated factor ...9725e-71     264     24     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
23Q6CFJ2    1054   TOF1_YARLI Topoisomerase 1-associated factor ...9282e-69     257     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
24Q4PAB2    1251   TOF1_USTMA Topoisomerase 1-associated factor ...11691e-26     122     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
25P0CR92    1074   TOF1_CRYNJ Topoisomerase 1-associated factor ...7972e-24     115     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
26P0CR93    1074   TOF1_CRYNB Topoisomerase 1-associated factor ...7965e-22     107     21     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
27Q9UNS1    1208   TIM_HUMAN Protein timeless homolog OS=Homo sa...1109.6     34.3     24     41GO:0000790; C:nuclear chromatin; IDA:HGNC.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; ISS:UniProtKB.::GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002009; P:morphogenesis of an epithelium; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0033261; P:regulation of S phase; IMP:HGNC.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q9R1X4    1197   TIM_MOUSE Protein timeless homolog OS=Mus mus...5910.000001     56.6     22     41
GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:MGI.
GO:0048754; P:branching morphogenesis of a tube; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:UniProtKB.::GO:0009790; P:embryo development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002009; P:morphogenesis of an epithelium; IEP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q9Z2Y1    1205   TIM_RAT Protein timeless homolog OS=Rattus no...5910.00008     50.8     21     41GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; ISS:UniProtKB.::GO:0001822; P:kidney development; IMP:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:RGD.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q54S12    499   TM104_DICDI Transmembrane protein 104 homolog...573.3     35.4     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
records
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