Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL272C
Length:
759
Number of sequences:
5887
Description:
YNL272C SEC2 SGDID:S000005216, Chr XIV from 129084-126805, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanyl-nucleotide exchange factor for the small G-protein Sec4p; essential for post-Golgi vesicle transport and for autophagy; associates with the exocyst, via exocyst subunit Sec15p, on secretory vesicles"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P17065    759   SEC2_YEAST Rab guanine nucleotide exchange fa...7590     1545     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0030133; C:transport vesicle; IDA:SGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:SGD.
GO:0006914; P:autophagy; IMP:SGD.::GO:0006887; P:exocytosis; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
2O13930    527   SEC2_SCHPO Rab guanine nucleotide exchange fa...1560.00000001     62     22     40GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005622; C:intracellular; IC:GOC.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:PomBase.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.
3Q62739    460   RAB3I_RAT Rab-3A-interacting protein OS=Rattu...1790.000008     52.8     31     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
4Q96QF0    476   RAB3I_HUMAN Rab-3A-interacting protein OS=Hom...3510.000009     52.8     23     41GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005813; C:centrosome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; IMP:BHF-UCL.::GO:0006893; P:Golgi to plasma membrane transport; TAS:BHF-UCL.::GO:0033365; P:protein localization to organelle; IMP:BHF-UCL.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
5Q18DN4    9159   HMU_HALWD Halomucin OS=Haloquadratum walsbyi ...1801.1     36.6     26     43GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0004180; F:carboxypeptidase activity; IEA:InterPro.
GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
6Q99NH3    377   R3GEF_RAT Guanine nucleotide exchange factor ...1790.001     45.8     25     48
GO:0019900; F:kinase binding; IDA:RGD.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:RGD.
7C6Y4C9    138   SPO13_SCHPO Sporulation-specific protein 13 O...920.002     42.4     38     61GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
8Q8IBP1    3429   YPF16_PLAF7 Uncharacterized protein PF07_0086...860.39     38.1     27     51GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
9Q8VDV3    383   R3GEF_MOUSE Guanine nucleotide exchange facto...1900.008     42.7     25     45
10Q9PTG8    931   TACC3_XENLA Transforming acidic coiled-coil-c...1130.11     39.7     27     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IPI:UniProtKB.
GO:0031369; F:translation initiation factor binding; IPI:UniProtKB.
GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.
11P0C6U3    4471   R1A_CVHN1 Replicase polyprotein 1a OS=Human c...1413.2     35     22     43GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
12P0C6X2    7182   R1AB_CVHN1 Replicase polyprotein 1ab OS=Human...1413.2     35     22     43GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
13P0C6U5    4421   R1A_CVHN5 Replicase polyprotein 1a OS=Human c...1750.38     38.1     22     41GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
14P0C6U4    4441   R1A_CVHN2 Replicase polyprotein 1a OS=Human c...1850.38     38.1     23     42GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
15P0C6X4    7132   R1AB_CVHN5 Replicase polyprotein 1ab OS=Human...1750.39     38.1     22     41GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
16P0C6X3    7152   R1AB_CVHN2 Replicase polyprotein 1ab OS=Human...1850.39     38.1     23     42GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
17Q18823    1633   LAM2_CAEEL Laminin-like protein lam-2 OS=Caen...1660.43     37.7     27     49
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
18Q2KJ58    390   R3GEF_BOVIN Guanine nucleotide exchange facto...1740.5     37.4     26     48
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
19Q7N3Y5    327   ZNTB_PHOLL Zinc transport protein ZntB OS=Pho...842.3     35     29     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005385; F:zinc ion transmembrane transporter activity; IEA:InterPro.
20Q06681    1438   YSP2_YEAST GRAM domain-containing protein YSP...892.7     35.4     33     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IMP:SGD.
21Q9UPY6    502   WASF3_HUMAN Wiskott-Aldrich syndrome protein ...773.4     34.7     31     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030041; P:actin filament polymerization; TAS:ProtInc.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
22Q8VHI6    501   WASF3_MOUSE Wiskott-Aldrich syndrome protein ...773.4     34.7     31     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
23Q00174    3712   LAMA_DROME Laminin subunit alpha OS=Drosophil...2003.7     35     22     43GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0048854; P:brain morphogenesis; IMP:FlyBase.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007507; P:heart development; IMP:FlyBase.::GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0031987; P:locomotion involved in locomotory behavior; IMP:FlyBase.::GO:0007498; P:mesoderm development; IEP:FlyBase.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.::GO:0001964; P:startle response; IMP:FlyBase.
24O31700    321   CSE15_BACSU Sporulation protein cse15 OS=Baci...874     34.3     30     59
GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
25P31732    432   OV71_ONCVO Muscle cell intermediate filament ...774.2     34.3     30     57GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
26P24043    3122   LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo s...1045.5     34.3     27     49GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
27Q9NTJ3    1288   SMC4_HUMAN Structural maintenance of chromoso...1316.7     33.9     29     52GO:0000796; C:condensin complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; TAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
28Q86MA7    862   PRQFV_APLCA Protein PRQFV-amide OS=Aplysia ca...746.9     33.9     31     54GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
29B1H2P5    882   CE120_XENTR Centrosomal protein of 120 kDa OS...818     33.5     33     56GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
30Q7Z4S6    1674   KI21A_HUMAN Kinesin-like protein KIF21A OS=Ho...899.3     33.5     30     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
31P05786    478   K2C8_BOVIN Keratin, type II cytoskeletal 8 OS...939.6     33.1     32     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0045095; C:keratin filament; IEA:InterPro.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
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