Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL262W
Length:
2222
Number of sequences:
5887
Description:
YNL262W POL2 SGDID:S000005206, Chr XIV from 148212-154880, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P21951    2222   DPOE_YEAST DNA polymerase epsilon catalytic s...22220     4615     100     100GO:0008622; C:epsilon DNA polymerase complex; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0033260; P:DNA replication involved in S phase; IMP:SGD.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0006273; P:lagging strand elongation; TAS:SGD.::GO:0006272; P:leading strand elongation; TAS:SGD.::GO:0006298; P:mismatch repair; TAS:SGD.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD.::GO:0006289; P:nucleotide-excision repair; TAS:SGD.
2Q6FNY7    2217   DPOE_CANGA DNA polymerase epsilon catalytic s...22290     3249     68     83GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
3Q6CUS7    2185   DPOE_KLULA DNA polymerase epsilon catalytic s...22130     3068     65     81GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
4Q752B8    2180   DPOE_ASHGO DNA polymerase epsilon catalytic s...22120     2972     64     79GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5Q6BNG2    2226   DPOE_DEBHA DNA polymerase epsilon catalytic s...22740     2613     56     73GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
6O93845    2207   DPOE_EMENI DNA polymerase epsilon catalytic s...22630     2149     49     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
7Q4WXH8    2230   DPOE_ASPFU DNA polymerase epsilon catalytic s...22770     2122     49     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
8P87154    2199   DPOE_SCHPO DNA polymerase epsilon catalytic s...22190     1956     47     64GO:0031261; C:DNA replication preinitiation complex; IC:PomBase.::GO:0008622; C:epsilon DNA polymerase complex; TAS:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IMP:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006270; P:DNA-dependent DNA replication initiation; IMP:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
9Q4PFV5    2305   DPOE_USTMA DNA polymerase epsilon catalytic s...23450     1823     42     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
10P0CN26    2250   DPOE_CRYNJ DNA polymerase epsilon catalytic s...22490     1804     43     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
11P0CN27    2250   DPOE_CRYNB DNA polymerase epsilon catalytic s...22490     1804     43     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
12Q6C4J0    2183   DPOE_YARLI DNA polymerase epsilon catalytic s...22520     1690     41     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13Q9WVF7    2283   DPOE1_MOUSE DNA polymerase epsilon catalytic ...23120     1657     41     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
14Q07864    2286   DPOE1_HUMAN DNA polymerase epsilon catalytic ...1964e-29     132     32     57GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0003887; F:DNA-directed DNA polymerase activity; IMP:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006287; P:base-excision repair, gap-filling; IDA:UniProtKB.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:UniProtKB.::GO:0006270; P:DNA-dependent DNA replication initiation; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; IMP:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.::GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
15Q54RD4    2380   DPOE1_DICDI DNA polymerase epsilon catalytic ...1370.0000000006     68.9     30     50GO:0008622; C:epsilon DNA polymerase complex; ISS:dictyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006273; P:lagging strand elongation; ISS:dictyBase.::GO:0006272; P:leading strand elongation; ISS:dictyBase.::GO:0006298; P:mismatch repair; ISS:dictyBase.::GO:0006289; P:nucleotide-excision repair; ISS:dictyBase.
16Q58295    1634   DPOL_METJA DNA polymerase OS=JCM 10045 / NBRC...3618e-21     104     27     46
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
17O33845    1829   DPOL_THEAG DNA polymerase OS=Thermococcus agg...585.4     36.2     33     55
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
18P61876    775   DPOL_PYRWO DNA polymerase OS=Pyrococcus woese...2320.000007     55.1     26     41
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
19P61875    775   DPOL_PYRFU DNA polymerase OS=Pyrococcus furio...2320.000007     55.1     26     41
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
20P30317    1702   DPOL_THELI DNA polymerase OS=Thermococcus lit...3672e-17     93.2     29     46
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
21Q56366    775   DPOL_THES9 DNA polymerase OS=Thermococcus sp....3530.00001     54.3     23     39
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
22P56689    773   DPOL_THEGO DNA polymerase OS=Thermococcus gor...2320.00009     51.6     25     39
23Q51334    1312   DPOL_PYRSD DNA polymerase OS=Pyrococcus sp. (...2822.5     37     24     40
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
24Q9HH05    1668   DPOL_THEHY DNA polymerase OS=Thermococcus hyd...3410.00000000000005     82.4     27     45
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
25Q9HH84    1699   DPOL_THEG8 DNA polymerase OS=Thermococcus sp....4780.00000000000005     82     25     43
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
26O27276    586   DPOL_METTH DNA polymerase OS=thermoautotrophi...3710.00000000000006     80.9     25     43
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
27P77933    1671   DPOL_PYRKO DNA polymerase OS=(Thermococcus ko...4730.00000000000008     81.6     23     43
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
28O59610    1235   DPOL_PYRHO DNA polymerase OS=NBRC 100139 / OT...3260.13     41.2     22     39
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
29Q7SIG7    773   DPOL_DESST DNA polymerase OS=Desulfurococcus ...3420.46     39.3     25     39
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
30Q9HH06    775   DPOL_PYRGL DNA polymerase OS=Pyrococcus glyco...3470.018     43.9     24     38
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
31P74918    1523   DPOL_THEFM DNA polymerase OS=Thermococcus fum...566.4     35.8     38     48
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
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