Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL262W
Length:
2222
Number of sequences:
5887
Description:
YNL262W POL2 SGDID:S000005206, Chr XIV from 148212-154880, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61O57861    1431   DP2L_PYRHO DNA polymerase II large subunit OS...720.044     42.7     31     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
62P81409    1263   DP2L_PYRFU DNA polymerase II large subunit OS...720.047     42.7     31     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
63P95979    764   DPOL3_SULSO DNA polymerase 3 OS=P2). GN=dpo3 ...3210.056     42.4     24     42
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
64Q9V2F4    1455   DP2L_PYRAB DNA polymerase II large subunit OS...700.059     42.4     31     53
GO:0008408; F:3'-5' exonuclease activity; IEA:HAMAP.::GO:0003677; F:DNA binding; IEA:HAMAP.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:HAMAP.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0000738; P:DNA catabolic process, exonucleolytic; IEA:HAMAP.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006261; P:DNA-dependent DNA replication; IEA:HAMAP.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
65P30315    1094   DPOD1_PLAFK DNA polymerase delta catalytic su...3370.12     41.6     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
66Q5JET0    1798   DP2L_PYRKO DNA polymerase II large subunit OS...890.13     41.2     28     49
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
67Q3KSP1    1015   DPOL_EBVG DNA polymerase catalytic subunit OS...1150.16     40.8     30     49GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
68Q1HVC1    1015   DPOL_EBVA8 DNA polymerase catalytic subunit O...1150.16     40.8     30     49GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
69P03198    1015   DPOL_EBVB9 DNA polymerase catalytic subunit O...1150.17     40.8     30     49GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
70O05706    763   DPOL3_SULSH DNA polymerase 3 OS=Sulfolobus sh...3240.2     40.4     23     43
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
71P90829    1081   DPOD1_CAEEL DNA polymerase delta catalytic su...731.5     37.7     32     52GO:0043625; C:delta DNA polymerase complex; IBA:RefGenome.
GO:0008296; F:3'-5'-exodeoxyribonuclease activity; IBA:RefGenome.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IBA:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006287; P:base-excision repair, gap-filling; IBA:RefGenome.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0045004; P:DNA replication proofreading; IBA:RefGenome.::GO:0043137; P:DNA replication, removal of RNA primer; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0035188; P:hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; IBA:RefGenome.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0000084; P:S phase of mitotic cell cycle; IBA:RefGenome.
72O93745    959   DPOL1_AERPE DNA polymerase 1 OS=100138 / K1)....3070.48     39.3     23     41
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
73A0B8K5    1109   DP2L_METTP DNA polymerase II large subunit OS...710.89     38.5     30     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
74Q2FSF9    1286   DP2L_METHJ DNA polymerase II large subunit OS...691.1     38.1     25     55
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
75Q9LRE6    1105   DPOD1_ORYSJ DNA polymerase delta catalytic su...3811.1     38.1     21     39GO:0043625; C:delta DNA polymerase complex; ISS:RefGenome.
GO:0008296; F:3'-5'-exodeoxyribonuclease activity; ISS:RefGenome.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; ISS:RefGenome.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006287; P:base-excision repair, gap-filling; ISS:RefGenome.::GO:0045004; P:DNA replication proofreading; ISS:RefGenome.::GO:0043137; P:DNA replication, removal of RNA primer; ISS:RefGenome.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; ISS:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; ISS:RefGenome.::GO:0000084; P:S phase of mitotic cell cycle; ISS:RefGenome.
76A0RYM0    1112   DP2L_CENSY DNA polymerase II large subunit OS...691.4     37.7     25     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
77O36363    1026   DPOL_ALHV1 DNA polymerase catalytic subunit O...831.4     37.7     30     42GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
78Q12229    455   UBX3_YEAST UBX domain-containing protein 3 OS...1071.9     37     27     44GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
79Q55CW3    640   SAMKA_DICDI Probable serine/threonine-protein...792     37.4     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
80P30318    1014   DPOL_NPVLD DNA polymerase OS=Lymantria dispar...2542.2     37.4     22     42
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
81P15436    1097   DPOD_YEAST DNA polymerase delta catalytic sub...1442.9     37     25     38GO:0043625; C:delta DNA polymerase complex; IBA:RefGenome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008310; F:single-stranded DNA specific 3'-5' exodeoxyribonuclease activity; TAS:SGD.
GO:0006287; P:base-excision repair, gap-filling; IBA:RefGenome.::GO:0045004; P:DNA replication proofreading; IBA:RefGenome.::GO:0043137; P:DNA replication, removal of RNA primer; IDA:SGD.::GO:0006272; P:leading strand elongation; TAS:SGD.::GO:0006298; P:mismatch repair; NAS:SGD.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; IBA:RefGenome.::GO:0006301; P:postreplication repair; TAS:SGD.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0006278; P:RNA-dependent DNA replication; IDA:SGD.::GO:0000084; P:S phase of mitotic cell cycle; IBA:RefGenome.
82A7U6F1    1623   DPOL_CEV01 DNA polymerase OS=Chrysochromulina...503.2     36.6     36     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
83P09884    1462   DPOLA_HUMAN DNA polymerase alpha catalytic su...713.5     36.6     32     54GO:0005658; C:alpha DNA polymerase:primase complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005635; C:nuclear envelope; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001882; F:nucleoside binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0000076; P:DNA replication checkpoint; IBA:RefGenome.::GO:0006269; P:DNA replication, synthesis of RNA primer; IBA:RefGenome.::GO:0006270; P:DNA-dependent DNA replication initiation; IDA:UniProtKB.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006273; P:lagging strand elongation; IDA:UniProtKB.::GO:0006272; P:leading strand elongation; IDA:UniProtKB.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; IDA:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.::GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
84Q9DKT8    1041   DPOL_ELHVK DNA polymerase catalytic subunit O...3184.2     36.2     21     34GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004523; F:ribonuclease H activity; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
85Q92784    378   DPF3_HUMAN Zinc finger protein DPF3 OS=Homo s...664.3     35.8     26     50GO:0071565; C:nBAF complex; ISS:UniProtKB.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86P58269    378   DPF3_MOUSE Zinc finger protein DPF3 OS=Mus mu...664.3     35.8     26     50GO:0071565; C:nBAF complex; IDA:UniProtKB.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87P06781    192   RHO2_YEAST GTP-binding protein RHO2 OS=Saccha...1144.9     35     25     54GO:0005622; C:intracellular; TAS:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0004871; F:signal transducer activity; TAS:SGD.
GO:0007015; P:actin filament organization; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.::GO:0007017; P:microtubule-based process; TAS:SGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:SGD.
88Q9E6N9    1220   DPOL_GAHVM DNA polymerase catalytic subunit O...3625.8     35.8     22     40GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004523; F:ribonuclease H activity; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
89Q9VYD1    2313   C1716_DROME Probable histone-lysine N-methylt...386.9     35.8     45     68GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:FlyBase.::GO:0051219; F:phosphoprotein binding; IPI:FlyBase.
GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
90P21402    988   DPOL_FOWPN DNA polymerase OS=Fowlpox virus (s...1028.4     35.4     26     39
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
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