UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL262W

Length:

2222

Number of sequences:

5887

Description:

YNL262W POL2 SGDID:S000005206, Chr XIV from 148212-154880, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P74918	1523	DPOL_THEFM DNA polymerase OS=Thermococcus fum...	56	6.4	35.8	38	48
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
32	P0CL77	771	DPOL_PYRAB DNA polymerase 1 OS=Pyrococcus aby...	388	0.0002	50.1	23	40
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
33	P0CL76	771	DPOL_PYRAY DNA polymerase 1 OS=Pyrococcus aby...	388	0.00007	51.6	23	40
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
34	O29753	781	DPOL_ARCFU DNA polymerase OS=9628 / NBRC 1001...	355	0.000005	55.5	21	40
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
35	Q90162	990	DPOL_NPVCF DNA polymerase OS=Choristoneura fu...	277	0.000003	56.6	23	42
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
36	P41712	986	DPOL_NPVBM DNA polymerase OS=Bombyx mori nucl...	245	0.000003	56.2	24	44
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
37	P18131	984	DPOL_NPVAC DNA polymerase OS=Autographa calif...	245	0.000004	56.2	24	45
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
38	Q83948	985	DPOL_NPVOP DNA polymerase OS=Orgyia pseudotsu...	346	3.2	36.6	23	38
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
39	P52025	824	DPOL_METVO DNA polymerase OS=Methanococcus vo...	202	0.005	45.8	27	41
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
40	P21189	783	DPO2_ECOLI DNA polymerase II OS=Escherichia c...	233	0.00002	53.5	26	41
									GO:0008296; F:3'-5'-exodeoxyribonuclease activity; IDA:EcoCyc.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0045004; P:DNA replication proofreading; IDA:EcoCyc.::GO:0009432; P:SOS response; IEP:EcoCyc.
41	P30316	1086	DPOD_SCHPO DNA polymerase delta catalytic sub...	294	0.00008	51.6	22	41	GO:0043625; C:delta DNA polymerase complex; TAS:PomBase.
									GO:0008296; F:3'-5'-exodeoxyribonuclease activity; ISS:RefGenome.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006287; P:base-excision repair, gap-filling; ISS:RefGenome.::GO:0045004; P:DNA replication proofreading; ISS:RefGenome.::GO:0043137; P:DNA replication, removal of RNA primer; TAS:PomBase.::GO:0000731; P:DNA synthesis involved in DNA repair; TAS:PomBase.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IMP:PomBase.::GO:0006297; P:nucleotide-excision repair, DNA gap filling; ISS:RefGenome.::GO:0000084; P:S phase of mitotic cell cycle; ISS:RefGenome.
42	P26811	882	DPOL1_SULSO DNA polymerase 1 OS=P2). GN=dpo1 ...	303	0.0001	51.2	24	41
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
43	O93746	803	DPOL2_AERPE DNA polymerase 2 OS=100138 / K1)....	374	0.0002	50.8	21	39
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
44	O50607	872	DPOL1_SULOH DNA polymerase 1 OS=Sulfurisphaer...	231	0.0005	48.9	26	42
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
45	P95690	876	DPOL1_SULAC DNA polymerase 1 OS=NBRC 15157 / ...	231	0.0005	48.9	26	42
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
46	P43139	1244	DPOL_ASFL6 DNA polymerase beta OS=African swi...	115	0.001	48.1	32	46
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
47	P0C974	1196	DPOL_ASFK5 DNA polymerase beta OS=African swi...	121	0.005	45.8	31	46
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
48	O27579	1092	DP2L_METTH DNA polymerase II large subunit OS...	82	0.009	45.1	26	54
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
									GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
49	Q196U0	1141	DPOL_IIV3 DNA polymerase 120R OS=Invertebrate...	341	0.009	45.1	23	41
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
50	P0C973	1199	DPOL_ASFWA DNA polymerase beta OS=(ASFV). GN=...	115	0.009	45.1	31	45
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
51	P0C971	1202	DPOL_ASFP4 DNA polymerase beta OS=Pr4/1996) (...	115	0.009	45.1	31	45
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
52	Q9LVN7	1095	DPOD1_ARATH DNA polymerase delta catalytic su...	507	0.01	45.1	19	38	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
53	P42489	1207	DPOL_ASFB7 DNA polymerase beta OS=(ASFV). GN=...	115	0.01	45.1	31	45
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
54	Q54SV8	1509	DPOLA_DICDI DNA polymerase alpha catalytic su...	83	1.2	38.1	31	48	GO:0005658; C:alpha DNA polymerase:primase complex; ISS:dictyBase.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IBA:RefGenome.::GO:0001882; F:nucleoside binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; ISS:dictyBase.
									GO:0000076; P:DNA replication checkpoint; IBA:RefGenome.::GO:0006269; P:DNA replication, synthesis of RNA primer; IBA:RefGenome.::GO:0000731; P:DNA synthesis involved in DNA repair; ISS:dictyBase.::GO:0006270; P:DNA-dependent DNA replication initiation; ISS:dictyBase.::GO:0006273; P:lagging strand elongation; ISS:dictyBase.::GO:0006272; P:leading strand elongation; ISS:dictyBase.::GO:0000084; P:S phase of mitotic cell cycle; IBA:RefGenome.
55	P0C972	1206	DPOL_ASFM2 DNA polymerase beta OS=African swi...	115	0.018	43.9	31	45
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
56	Q6R7C9	1878	DPOL_OSHVF DNA polymerase OS=herpesvirus). GN...	77	0.019	44.3	35	53
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
57	A7U6F2	1206	DPOL_POV01 DNA polymerase OS=Pyramimonas orie...	55	0.029	43.5	40	55
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
58	P54358	1092	DPOD1_DROME DNA polymerase delta catalytic su...	119	0.029	43.5	23	51	GO:0043625; C:delta DNA polymerase complex; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.
									GO:0008296; F:3'-5'-exodeoxyribonuclease activity; IDA:FlyBase.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
59	O45228	616	PROD_CAEEL Proline dehydrogenase 1, mitochond...	177	0.035	42.7	27	42	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0071949; F:FAD binding; ISS:UniProtKB.::GO:0004657; F:proline dehydrogenase activity; ISS:UniProtKB.
									GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.::GO:0006562; P:proline catabolic process; IEA:InterPro.
60	P46588	1038	DPOD_CANAX DNA polymerase delta catalytic sub...	295	0.042	42.7	22	38	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
61	O57861	1431	DP2L_PYRHO DNA polymerase II large subunit OS...	72	0.044	42.7	31	51
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
									GO:0006308; P:DNA catabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.

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