Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL251C
Length:
575
Number of sequences:
5887
Description:
YNL251C NRD1 SGDID:S000005195, Chr XIV from 174315-172588, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex mediates termination of snoRNAs and cryptic unstable transcripts (CUTs); interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), preferentially at phosphorylated Ser5; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; required for 3' end maturation of nonpolyadenylated RNAs"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53617    575   NRD1_YEAST Protein NRD1 OS=Saccharomyces cere...5750     1191     100     100GO:0035649; C:Nrd1 complex; IDA:SGD.::GO:0005634; C:nucleus; IPI:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001068; F:transcription regulatory region RNA binding; IDA:SGD.
GO:0030847; P:termination of RNA polymerase II transcription, exosome-dependent; IMP:SGD.
2Q9UTE3    620   SEB1_SCHPO Rpb7-binding protein seb1 OS=Schiz...1464e-19     94.7     34     56GO:0035649; C:Nrd1 complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031123; P:RNA 3'-end processing; ISS:PomBase.::GO:0030847; P:termination of RNA polymerase II transcription, exosome-dependent; ISS:PomBase.
3O95104    1147   SFR15_HUMAN Splicing factor, arginine/serine-...1650.00001     52     22     42GO:0005634; C:nucleus; IDA:HPA.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
4Q4W9V0    383   SLT11_ASPFU Pre-mRNA-splicing factor slt11 OS...1370.0001     48.1     29     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5Q63623    1268   SCAF8_RAT Protein SCAF8 OS=Rattus norvegicus ...1280.13     38.9     23     45GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IMP:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IMP:RGD.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; IMP:RGD.
6Q6DID3    1268   SCAF8_MOUSE Protein SCAF8 OS=Mus musculus (Mo...1280.12     39.3     23     45GO:0016363; C:nuclear matrix; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
7Q9UPN6    1271   SCAF8_HUMAN Protein SCAF8 OS=Homo sapiens (Hu...1380.001     45.4     22     43GO:0016363; C:nuclear matrix; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0043175; F:RNA polymerase core enzyme binding; IPI:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
8P32831    672   NGR1_YEAST Negative growth regulatory protein...700.002     45.1     33     51GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.::GO:0010494; C:cytoplasmic stress granule; IDA:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0061158; P:3'-UTR-mediated mRNA destabilization; IDA:SGD.::GO:0007005; P:mitochondrion organization; IMP:SGD.
9Q6XE24    437   RBMS3_HUMAN RNA-binding motif, single-strande...600.002     44.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
10Q5RBD3    436   RBMS3_PONAB RNA-binding motif, single-strande...600.002     44.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
11Q8BWL5    431   RBMS3_MOUSE RNA-binding motif, single-strande...600.002     44.3     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
12Q7RUX3    385   SLT11_NEUCR Pre-mRNA-splicing factor slt-11 O...830.004     43.5     28     49GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
13Q3ZBP3    403   RBMS1_BOVIN RNA-binding motif, single-strande...600.004     43.5     40     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
14P29558    406   RBMS1_HUMAN RNA-binding motif, single-strande...600.004     43.1     40     60GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003690; F:double-stranded DNA binding; NAS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0003697; F:single-stranded DNA binding; NAS:UniProtKB.
GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0006396; P:RNA processing; TAS:ProtInc.
15Q5PQP1    403   RBMS1_RAT RNA-binding motif, single-stranded-...600.005     43.1     37     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
16Q91W59    403   RBMS1_MOUSE RNA-binding motif, single-strande...600.007     42.7     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
17F4I3B3    445   RB47A_ARATH Polyadenylate-binding protein RBP...700.008     42.7     33     49GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0034605; P:cellular response to heat; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
18Q9LEB4    409   RBP45_NICPL Polyadenylate-binding protein RBP...700.013     42     30     49GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
19Q3ZC34    407   RBMS2_BOVIN RNA-binding motif, single-strande...600.017     41.6     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
20Q8VC70    383   RBMS2_MOUSE RNA-binding motif, single-strande...600.019     41.2     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
21Q15434    407   RBMS2_HUMAN RNA-binding motif, single-strande...600.022     41.2     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.
GO:0006396; P:RNA processing; TAS:ProtInc.
22Q0JDM0    903   C3H27_ORYSJ Zinc finger CCCH domain-containin...560.024     41.2     34     59
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q4KLH4    522   PSPC1_RAT Paraspeckle component 1 OS=Rattus n...920.033     40.8     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q8R326    523   PSPC1_MOUSE Paraspeckle component 1 OS=Mus mu...920.033     40.8     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0042382; C:paraspeckles; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q8WXF1    523   PSPC1_HUMAN Paraspeckle component 1 OS=Homo s...920.037     40.4     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q5ZK88    523   PSPC1_CHICK Paraspeckle component 1 OS=Gallus...910.042     40.4     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q5SNN4    482   C3H40_ORYSJ Zinc finger CCCH domain-containin...840.048     40     30     45
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
28Q6NZZ9    425   RBM22_DANRE Pre-mRNA-splicing factor RBM22 OS...710.049     40     30     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0036002; F:pre-mRNA binding; ISS:UniProtKB.::GO:0017069; F:snRNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009790; P:embryo development; IMP:ZFIN.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:UniProtKB.::GO:0033120; P:positive regulation of RNA splicing; ISS:UniProtKB.
29Q1LZD9    520   PSPC1_BOVIN Paraspeckle component 1 OS=Bos ta...920.053     40     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q5ZM16    420   RBM22_CHICK Pre-mRNA-splicing factor RBM22 OS...810.054     40     30     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0005487; F:nucleocytoplasmic transporter activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0036002; F:pre-mRNA binding; ISS:UniProtKB.::GO:0017069; F:snRNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033554; P:cellular response to stress; ISS:UniProtKB.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:UniProtKB.::GO:0090316; P:positive regulation of intracellular protein transport; ISS:UniProtKB.::GO:0033120; P:positive regulation of RNA splicing; ISS:UniProtKB.
31Q6Z358    486   C3H49_ORYSJ Zinc finger CCCH domain-containin...840.057     40     29     45
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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