Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL250W
Length:
1312
Number of sequences:
5887
Description:
YNL250W RAD50 SGDID:S000005194, Chr XIV from 175410-179348, Genome Release 64-1-1, Verified ORF, "Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P12753    1312   RAD50_YEAST DNA repair protein RAD50 OS=Sacch...13120     2638     100     100GO:0005739; C:mitochondrion; IDA:SGD.::GO:0030870; C:Mre11 complex; IPI:SGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004017; F:adenylate kinase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0003691; F:double-stranded telomeric DNA binding; IDA:SGD.::GO:0051880; F:G-quadruplex DNA binding; IDA:SGD.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043047; F:single-stranded telomeric DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006284; P:base-excision repair; IMP:SGD.::GO:0000727; P:double-strand break repair via break-induced replication; TAS:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0042138; P:meiotic DNA double-strand break formation; TAS:SGD.::GO:0000706; P:meiotic DNA double-strand break processing; TAS:SGD.::GO:0032078; P:negative regulation of endodeoxyribonuclease activity; IDA:SGD.::GO:0000722; P:telomere maintenance via recombination; IMP:SGD.
2P70388    1312   RAD50_MOUSE DNA repair protein RAD50 OS=Mus m...13508e-136     455     29     52GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0030870; C:Mre11 complex; IEA:InterPro.::GO:0045120; C:pronucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
3Q9W252    1318   RAD50_DROME DNA repair protein RAD50 OS=Droso...13762e-124     424     28     51GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0030870; C:Mre11 complex; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0008104; P:protein localization; IMP:UniProtKB.::GO:0016233; P:telomere capping; IMP:FlyBase.::GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
4Q9UTJ8    1285   RAD50_SCHPO DNA repair protein rad50 OS=Schiz...4082e-97     345     44     68GO:0030870; C:Mre11 complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; TAS:PomBase.::GO:0003677; F:DNA binding; TAS:PomBase.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000724; P:double-strand break repair via homologous recombination; IGI:PomBase.::GO:0000734; P:gene conversion at mating-type locus, DNA repair synthesis; IMP:PomBase.::GO:0031573; P:intra-S DNA damage checkpoint; TAS:PomBase.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
5Q92878    1312   RAD50_HUMAN DNA repair protein RAD50 OS=Homo ...6643e-66     250     32     54GO:0030870; C:Mre11 complex; IDA:UniProtKB.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032508; P:DNA duplex unwinding; IMP:BHF-UCL.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0033674; P:positive regulation of kinase activity; IDA:BHF-UCL.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.::GO:0000019; P:regulation of mitotic recombination; IDA:UniProtKB.::GO:0007004; P:telomere maintenance via telomerase; IDA:UniProtKB.
6Q9JIL8    1312   RAD50_RAT DNA repair protein RAD50 OS=Rattus ...2312e-65     247     52     71GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000794; C:condensed nuclear chromosome; IDA:RGD.::GO:0016234; C:inclusion body; IDA:RGD.::GO:0030870; C:Mre11 complex; ISS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0030674; F:protein binding, bridging; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000075; P:cell cycle checkpoint; TAS:RGD.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0007131; P:reciprocal meiotic recombination; TAS:RGD.::GO:0000019; P:regulation of mitotic recombination; ISS:UniProtKB.::GO:0007004; P:telomere maintenance via telomerase; ISS:UniProtKB.
7Q8SRK6    1247   RAD50_ENCCU DNA repair protein RAD50 OS=Encep...3313e-65     246     40     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
8Q9SL02    1316   RAD50_ARATH DNA repair protein RAD50 OS=Arabi...8671e-61     235     29     49GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0030870; C:Mre11 complex; TAS:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; IMP:TAIR.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006312; P:mitotic recombination; IMP:TAIR.::GO:0016233; P:telomere capping; IMP:TAIR.
9Q54CS9    1351   RAD50_DICDI DNA repair protein RAD50 OS=Dicty...2142e-57     222     49     69GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0030870; C:Mre11 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:dictyBase.::GO:0003690; F:double-stranded DNA binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030674; F:protein binding, bridging; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:dictyBase.
GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0006303; P:double-strand break repair via nonhomologous end joining; ISS:dictyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000019; P:regulation of mitotic recombination; ISS:UniProtKB.::GO:0007004; P:telomere maintenance via telomerase; ISS:UniProtKB.
10C6KSQ6    2236   RAD50_PLAF7 Probable DNA repair protein RAD50...2746e-46     186     36     59GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000014; F:single-stranded DNA specific endodeoxyribonuclease activity; ISS:GeneDB_Pfalciparum.
GO:0006302; P:double-strand break repair; ISS:GeneDB_Pfalciparum.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
11O44199    1298   RAD50_CAEEL DNA repair protein rad-50 OS=Caen...2051e-37     158     41     56GO:0030870; C:Mre11 complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
12Q8TXI4    876   RAD50_METKA DNA double-strand break repair Ra...750.00001     53.9     39     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
13O26640    837   RAD50_METTH DNA double-strand break repair Ra...4160.00000002     62.8     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
14D4GUK1    893   RAD50_HALVD DNA double-strand break repair Ra...3780.000004     55.1     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
15Q5JHN1    883   RAD50_PYRKO DNA double-strand break repair Ra...2380.00003     52.4     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
16Q9YFZ1    919   RAD50_AERPE DNA double-strand break repair Ra...2240.0002     50.1     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
17Q96YR5    879   RAD50_SULTO DNA double-strand break repair Ra...390.036     42.4     41     72
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
18O33600    886   RAD50_SULAC DNA double-strand break repair Ra...1600.004     45.4     23     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
19B8CW13    1185   SMC_HALOH Chromosome partition protein Smc OS...800.0002     49.7     35     54GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
20O29230    886   RAD50_ARCFU DNA double-strand break repair Ra...3460.028     42.4     20     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
21Q8PUY4    1070   RAD50_METMA DNA double-strand break repair Ra...1170.0005     48.1     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
22O58687    879   RAD50_PYRHO DNA double-strand break repair Ra...3398.5     34.3     24     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
23Q97WH0    864   RAD50_SULSO DNA double-strand break repair Ra...2940.077     41.2     23     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
24Q5ZJY5    1065   SMC5_CHICK Structural maintenance of chromoso...1290.001     47.4     26     48GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.::GO:0030915; C:Smc5-Smc6 complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0090398; P:cellular senescence; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.::GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.::GO:0000722; P:telomere maintenance via recombination; ISS:UniProtKB.
25P62134    993   RAD50_METMP DNA double-strand break repair Ra...390.26     39.3     38     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
26Q24U48    1198   SMC_DESHY Chromosome partition protein Smc OS...1020.001     47     28     54GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
27Q9HLR8    896   RAD50_THEAC DNA double-strand break repair Ra...3890.22     39.7     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
28P58302    895   RAD50_THEVO DNA double-strand break repair Ra...820.42     38.9     27     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
29Q9NUQ8    709   ABCF3_HUMAN ATP-binding cassette sub-family F...1380.003     45.8     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
30Q5R9Z5    709   ABCF3_PONAB ATP-binding cassette sub-family F...1380.003     45.8     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
31Q8K268    709   ABCF3_MOUSE ATP-binding cassette sub-family F...950.004     45.1     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 184 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::