Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL250W
Length:
1312
Number of sequences:
5887
Description:
YNL250W RAD50 SGDID:S000005194, Chr XIV from 175410-179348, Genome Release 64-1-1, Verified ORF, "Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q1GAD3    252   PSTB_LACDA Phosphate import ATP-binding prote...1011.5     36.2     26     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
122O54692    779   ZW10_MOUSE Centromere/kinetochore protein zw1...1731.6     36.6     29     46GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005828; C:kinetochore microtubule; ISS:HGNC.::GO:0005634; C:nucleus; ISS:HGNC.::GO:0000922; C:spindle pole; ISS:HGNC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:HGNC.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:HGNC.::GO:0006461; P:protein complex assembly; ISS:HGNC.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; ISS:HGNC.
123Q8CGB3    1411   UACA_MOUSE Uveal autoantigen with coiled-coil...3351.6     37     24     46GO:0043293; C:apoptosome; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005635; C:nuclear envelope; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:MGI.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0042307; P:positive regulation of protein import into nucleus; IMP:MGI.::GO:0009411; P:response to UV; IMP:MGI.
124Q02224    2701   CENPE_HUMAN Centromere-associated protein E O...2811.7     37     26     51GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0005634; C:nucleus; IMP:UniProtKB.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043515; F:kinetochore binding; IDA:UniProtKB.::GO:0003777; F:microtubule motor activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051382; P:kinetochore assembly; NAS:UniProtKB.::GO:0007079; P:mitotic chromosome movement towards spindle pole; TAS:ProtInc.::GO:0000089; P:mitotic metaphase; TAS:ProtInc.::GO:0007080; P:mitotic metaphase plate congression; TAS:ProtInc.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
125Q8N442    669   GUF1_HUMAN Translation factor GUF1, mitochond...2411.9     36.6     26     47GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006412; P:translation; IEA:UniProtKB-KW.
126Q8HYC0    445   CLC4M_PANTR C-type lectin domain family 4 mem...2722     36.2     24     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005537; F:mannose binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
127Q4V8C2    777   ZW10_RAT Centromere/kinetochore protein zw10 ...1732     36.6     29     46GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005828; C:kinetochore microtubule; ISS:HGNC.::GO:0005634; C:nucleus; ISS:HGNC.::GO:0000922; C:spindle pole; ISS:HGNC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:HGNC.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:HGNC.::GO:0006461; P:protein complex assembly; ISS:HGNC.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007096; P:regulation of exit from mitosis; ISS:HGNC.
128Q2PMN9    90   RR15_SOYBN 30S ribosomal protein S15, chlorop...722.1     33.5     33     54GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:UniProtKB-KW.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
129O42649    1194   SMC3_SCHPO Structural maintenance of chromoso...1062.1     36.6     27     46GO:0000794; C:condensed nuclear chromosome; IC:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0030892; C:mitotic cohesin complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:PomBase.
130Q8HY00    404   CD209_PONPY CD209 antigen OS=Pongo pygmaeus (...2432.1     36.2     24     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005537; F:mannose binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
131P02534    412   K1M1_SHEEP Keratin, type I microfibrillar 48 ...2982.2     36.2     22     44GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
132Q21JQ9    228   LOLD_SACD2 Lipoprotein-releasing system ATP-b...652.3     35.4     32     49GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0042954; F:lipoprotein transporter activity; IEA:InterPro.
133Q9NRC6    3674   SPTN5_HUMAN Spectrin beta chain, brain 4 OS=H...972.3     36.6     28     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; NAS:UniProtKB.::GO:0008091; C:spectrin; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.
134B0LKP1    455   KRT35_SHEEP Keratin, type I cuticular Ha5 OS=...3002.4     35.8     22     43GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
135P58301    882   RAD50_PYRFU DNA double-strand break repair Ra...422.5     36.2     33     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
136Q46KX0    336   FMT_PROMT Methionyl-tRNA formyltransferase OS...872.5     35.8     40     59
GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:EC.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
137Q9LS42    689   CASP_ARATH Protein CASP OS=Arabidopsis thalia...3422.5     36.2     24     47GO:0030173; C:integral to Golgi membrane; IEA:InterPro.
GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
138A5A6M5    416   K1H1_PANTR Keratin, type I cuticular Ha1 OS=P...2847.9     34.3     25     48GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
139A3DHZ7    369   RECF_CLOTH DNA replication and repair protein...422.6     35.8     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009432; P:SOS response; IEA:UniProtKB-KW.
140Q15323    416   K1H1_HUMAN Keratin, type I cuticular Ha1 OS=H...2849     34.3     25     48GO:0005882; C:intermediate filament; TAS:ProtInc.
GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0008544; P:epidermis development; TAS:ProtInc.
141Q0P5J7    454   KRT35_BOVIN Keratin, type I cuticular Ha5 OS=...3002.9     35.8     21     43GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
142Q9Y7S2    396   YQO3_SCHPO UPF0612 protein C569.003 OS=Schizo...1312.9     35.8     22     51GO:0005829; C:cytosol; IDA:PomBase.
143Q9H2X3    399   CLC4M_HUMAN C-type lectin domain family 4 mem...2483     35.4     26     45GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0030369; F:ICAM-3 receptor activity; NAS:UniProtKB.::GO:0005537; F:mannose binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042605; F:peptide antigen binding; NAS:UniProtKB.::GO:0046790; F:virion binding; TAS:UniProtKB.
GO:0009988; P:cell-cell recognition; TAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0046795; P:intracellular virion transport; TAS:UniProtKB.::GO:0007159; P:leukocyte cell-cell adhesion; NAS:UniProtKB.::GO:0046968; P:peptide antigen transport; NAS:UniProtKB.::GO:0019062; P:viral attachment to host cell; TAS:UniProtKB.::GO:0019079; P:viral genome replication; NAS:UniProtKB.
144Q669P3    234   LOLD_YERPS Lipoprotein-releasing system ATP-b...653     35     29     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0042954; F:lipoprotein transporter activity; IEA:InterPro.
145Q6IFW2    431   K1C40_RAT Keratin, type I cytoskeletal 40 OS=...2943.1     35.4     26     43GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
146Q6IFX3    439   K1C40_MOUSE Keratin, type I cytoskeletal 40 O...2943.2     35.4     25     43GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
147Q1CI46    234   LOLD_YERPN Lipoprotein-releasing system ATP-b...653.3     35     29     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0042954; F:lipoprotein transporter activity; IEA:InterPro.
148Q8ZFR4    234   LOLD_YERPE Lipoprotein-releasing system ATP-b...653.3     35     29     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0042954; F:lipoprotein transporter activity; IEA:InterPro.
149Q1C6Q8    234   LOLD_YERPA Lipoprotein-releasing system ATP-b...653.3     35     29     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0042954; F:lipoprotein transporter activity; IEA:InterPro.
150P44884    506   MGLA_HAEIN Galactose/methyl galactoside impor...1533.3     35.4     25     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015407; F:monosaccharide-transporting ATPase activity; IEA:EC.
151Q4QM77    506   MGLA_HAEI8 Galactose/methyl galactoside impor...1533.3     35.4     25     48GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015407; F:monosaccharide-transporting ATPase activity; IEA:EC.
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