Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL246W
Length:
264
Number of sequences:
5887
Description:
YNL246W VPS75 SGDID:S000005190, Chr XIV from 185460-185491,185587-186349, Genome Release 64-1-1, Verified ORF, "NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53853    264   VPS75_YEAST Vacuolar protein sorting-associat...2640     539     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0010698; F:acetyltransferase activator activity; IMP:SGD.::GO:0042393; F:histone binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:SGD.::GO:0006334; P:nucleosome assembly; IDA:SGD.::GO:0035066; P:positive regulation of histone acetylation; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
2Q9HGN2    244   YO48_SCHPO Putative nucleosome assembly prote...2210.00000000002     65.5     29     47GO:0005634; C:nucleus; ISS:PomBase.
GO:0010698; F:acetyltransferase activator activity; ISS:PomBase.::GO:0042393; F:histone binding; ISS:PomBase.
GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0035066; P:positive regulation of histone acetylation; ISS:PomBase.
3P53997    269   SET_DROME Protein SET OS=Drosophila melanogas...2200.000000001     60.8     26     43GO:0005634; C:nucleus; IEA:InterPro.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
4Q9H0U9    437   TSYL1_HUMAN Testis-specific Y-encoded-like pr...1880.0004     44.7     22     38GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
5Q69ZB3    406   TSYL5_MOUSE Testis-specific Y-encoded-like pr...2110.0006     44.3     21     40GO:0005634; C:nucleus; IEA:InterPro.
GO:0071480; P:cellular response to gamma radiation; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
6Q5R5G8    438   TSYL1_PONAB Testis-specific Y-encoded-like pr...1880.0006     44.3     22     38GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
7O88852    379   TSYL1_MOUSE Testis-specific Y-encoded-like pr...1870.003     42     22     38GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
8Q0P5N2    432   TSYL1_BOVIN Testis-specific Y-encoded-like pr...1830.003     42     20     38GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
9Q7TQI8    677   TSYL2_MOUSE Testis-specific Y-encoded-like pr...1810.005     41.6     22     36
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q86VY4    417   TSYL5_HUMAN Testis-specific Y-encoded-like pr...1720.025     39.3     22     40GO:0005634; C:nucleus; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0071480; P:cellular response to gamma radiation; IMP:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
11Q9H2G4    693   TSYL2_HUMAN Testis-specific Y-encoded-like pr...1770.048     38.5     20     34GO:0005813; C:centrosome; IDA:HPA.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0000182; F:rDNA binding; NAS:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045786; P:negative regulation of cell cycle; NAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0008156; P:negative regulation of DNA replication; IDA:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q9BE64    695   TSYL2_MACFA Testis-specific Y-encoded-like pr...1770.081     37.7     21     34GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008156; P:negative regulation of DNA replication; ISS:UniProtKB.::GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13P13825    253   ASP_PLAFS Aspartic acid-rich protein OS=Plasm...900.28     35.8     30     49GO:0005634; C:nucleus; IEA:InterPro.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
14Q01105    290   SET_HUMAN Protein SET OS=Homo sapiens (Human)...2182.1     33.1     20     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0042393; F:histone binding; TAS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc.::GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.
GO:0006260; P:DNA replication; TAS:ProtInc.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0035067; P:negative regulation of histone acetylation; TAS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006913; P:nucleocytoplasmic transport; NAS:UniProtKB.::GO:0006334; P:nucleosome assembly; TAS:ProtInc.::GO:0006337; P:nucleosome disassembly; TAS:UniProtKB.
15Q8C0W1    906   ANMY1_MOUSE Ankyrin repeat and MYND domain-co...782.1     33.5     33     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
16Q9EQU5    289   SET_MOUSE Protein SET OS=Mus musculus (Mouse)...2182.5     32.7     20     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
17Q63945    289   SET_RAT Protein SET OS=Rattus norvegicus (Rat...2182.8     32.7     20     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0006334; P:nucleosome assembly; IEA:InterPro.
18Q18240    312   SPR2_CAEEL Suppressor of presenilin-2 OS=Caen...2095.5     32     20     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006334; P:nucleosome assembly; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19B5Y9D1    273   FOLD_COPPD Bifunctional protein FolD OS=Copro...516.6     31.6     39     47
GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
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