Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL243W
Length:
968
Number of sequences:
5887
Description:
YNL243W SLA2 SGDID:S000005187, Chr XIV from 188051-190957, Genome Release 64-1-1, Verified ORF, "Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33338    968   SLA2_YEAST Protein SLA2 OS=Saccharomyces cere...9680     2002     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.
GO:0007015; P:actin filament organization; IMP:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0006887; P:exocytosis; TAS:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD.
2Q9P6L5    1102   SLA2_SCHPO Endocytosis protein end4 OS=Schizo...4241e-64     240     38     56GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; ISS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0031580; P:membrane raft distribution; IMP:PomBase.
3O75146    1068   HIP1R_HUMAN Huntingtin-interacting protein 1-...10403e-47     187     23     42GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
4O00291    1037   HIP1_HUMAN Huntingtin-interacting protein 1 O...10202e-45     181     24     45GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; TAS:ProtInc.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030276; F:clathrin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0048268; P:clathrin coat assembly; IDA:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9JKY5    1068   HIP1R_MOUSE Huntingtin-interacting protein 1-...10052e-42     172     23     43GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IDA:MGI.::GO:0005856; C:cytoskeleton; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0006898; P:receptor-mediated endocytosis; ISS:UniProtKB.
6Q02328    927   SLAP2_CAEEL Huntington interacting protein re...5591e-17     92.4     21     41GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0030421; P:defecation; IMP:WormBase.::GO:0032502; P:developmental process; IMP:WormBase.::GO:0007638; P:mechanosensory behavior; IMP:WormBase.::GO:0007269; P:neurotransmitter secretion; IMP:WormBase.::GO:0008104; P:protein localization; IMP:WormBase.::GO:0050954; P:sensory perception of mechanical stimulus; IMP:WormBase.::GO:0007624; P:ultradian rhythm; IMP:WormBase.
7Q8VD75    1029   HIP1_MOUSE Huntingtin-interacting protein 1 O...3152e-20     100     23     49GO:0030665; C:clathrin coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IDA:UniProtKB.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q54K81    2614   TALB_DICDI Talin-B OS=Dictyostelium discoideu...2020.000000000000001     85.9     31     52GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0048102; P:autophagic cell death; IMP:dictyBase.::GO:0048870; P:cell motility; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
9P0CE95    2492   TALA1_DICDI Talin-A OS=Dictyostelium discoide...1990.0000000000005     77.4     32     48GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.
10P26039    2541   TLN1_MOUSE Talin-1 OS=Mus musculus (Mouse). G...1950.000000000001     75.9     33     51GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0007044; P:cell-substrate junction assembly; IMP:MGI.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:MGI.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
11Q9Y490    2541   TLN1_HUMAN Talin-1 OS=Homo sapiens (Human). G...1950.000000000002     75.9     33     51GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005911; C:cell-cell junction; IC:UniProtKB.::GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0005925; C:focal adhesion; NAS:UniProtKB.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IEA:InterPro.::GO:0030274; F:LIM domain binding; IPI:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.::GO:0017166; F:vinculin binding; IPI:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.::GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.
12Q9Y4G6    2542   TLN2_HUMAN Talin-2 OS=Homo sapiens (Human). G...2040.000000000003     75.1     33     49GO:0015629; C:actin cytoskeleton; NAS:UniProtKB.::GO:0005911; C:cell-cell junction; IC:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:InterPro.::GO:0045202; C:synapse; NAS:UniProtKB.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005158; F:insulin receptor binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0007155; P:cell adhesion; NAS:UniProtKB.::GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
13P54939    2541   TLN1_CHICK Talin-1 OS=Gallus gallus (Chicken)...2030.00000000005     71.2     31     49GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:HGNC.::GO:0005925; C:focal adhesion; IDA:HGNC.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
14Q71LX4    2375   TLN2_MOUSE Talin-2 OS=Mus musculus (Mouse). G...1310.00000002     62.4     36     53GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005916; C:fascia adherens; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:InterPro.::GO:0045202; C:synapse; IDA:MGI.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
15Q8ILR9    4662   YPF17_PLAF7 Protein PF14_0175 OS=Plasmodium f...1660.0002     49.3     27     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
16O60167    649   YHC3_SCHPO ENTH domain-containing protein C19...1190.052     41.2     29     49GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0030118; C:clathrin coat; IEA:InterPro.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.::GO:0030276; F:clathrin binding; ISS:PomBase.
GO:0048268; P:clathrin coat assembly; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; NAS:PomBase.
17Q9SA65    599   CAP4_ARATH Putative clathrin assembly protein...2730.053     41.2     25     40GO:0030118; C:clathrin coat; IEA:InterPro.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.::GO:0030276; F:clathrin binding; IEA:InterPro.
GO:0048268; P:clathrin coat assembly; IEA:InterPro.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
18Q8VYT2    601   CAP6_ARATH Putative clathrin assembly protein...750.67     37.4     32     51GO:0030118; C:clathrin coat; IEA:InterPro.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.::GO:0030276; F:clathrin binding; IEA:InterPro.
GO:0048268; P:clathrin coat assembly; IEA:InterPro.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
19Q60LV4    1969   MYO3_CAEBR Myosin-3 OS=Caenorhabditis briggsa...1621.1     37     27     51GO:0031672; C:A band; ISS:UniProtKB.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; ISS:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.
20O80931    367   AS1_ARATH Transcription factor AS1 OS=Arabido...1591.8     35.8     23     44GO:0000793; C:condensed chromosome; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0003677; F:DNA binding; IPI:TAIR.::GO:0042803; F:protein homodimerization activity; IPI:TAIR.
GO:0008356; P:asymmetric cell division; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0050832; P:defense response to fungus; IMP:TAIR.::GO:0010338; P:leaf formation; IGI:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009944; P:polarity specification of adaxial/abaxial axis; IMP:TAIR.::GO:0045088; P:regulation of innate immune response; IMP:TAIR.::GO:0009733; P:response to auxin stimulus; IEP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009739; P:response to gibberellin stimulus; IEP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009615; P:response to virus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q9LVD8    591   CAP7_ARATH Putative clathrin assembly protein...842.5     35.4     31     51GO:0030118; C:clathrin coat; IEA:InterPro.::GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.::GO:0030276; F:clathrin binding; IEA:InterPro.
GO:0048268; P:clathrin coat assembly; IEA:InterPro.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
22Q8TDY4    903   ASAP3_HUMAN Arf-GAP with SH3 domain, ANK repe...1323     35.4     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
23P37028    266   BTUF_ECOLI Vitamin B12-binding protein OS=Esc...884.5     34.3     31     55GO:0042597; C:periplasmic space; IDA:EcoliWiki.
GO:0031419; F:cobalamin binding; IDA:EcoliWiki.
GO:0006810; P:transport; IEA:UniProtKB-KW.
24P0A5P4    284   ERP_MYCTU Exported repetitive protein OS=Myco...744.6     34.3     36     41GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MTBBASE.
GO:0044119; P:growth of symbiont in host cell; IDA:MTBBASE.::GO:0009405; P:pathogenesis; IMP:MTBBASE.
25P0A5P5    284   ERP_MYCBO Exported repetitive protein OS=Myco...744.6     34.3     36     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
26Q8CWD2    266   BTUF_ECOL6 Vitamin B12-binding protein OS=Esc...884.9     34.3     31     55GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
27P13541    1940   MYH3_MOUSE Myosin-3 OS=Mus musculus (Mouse). ...1374.9     35     30     48GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
28P12847    1940   MYH3_RAT Myosin-3 OS=Rattus norvegicus (Rat)....1375.1     34.7     30     48GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
29Q2M243    656   CCD27_HUMAN Coiled-coil domain-containing pro...1685.4     34.7     28     46
30O42903    401   YBAC_SCHPO GRIP domain-containing protein C11...1015.4     34.3     33     50GO:0005796; C:Golgi lumen; IEA:UniProtKB-SubCell.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
31Q5M729    539   OPD23_ARATH Dihydrolipoyllysine-residue acety...645.6     34.3     36     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006090; P:pyruvate metabolic process; IEA:InterPro.
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