Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL238W
Length:
814
Number of sequences:
5887
Description:
YNL238W KEX2 SGDID:S000005182, Chr XIV from 202428-204872, Genome Release 64-1-1, Verified ORF, "Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P29140    321   ISP_BACCS Intracellular alkaline protease OS=...2580.2     38.5     27     41
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
92P40903    467   ISP6_SCHPO Sexual differentiation process put...2610.51     37.4     26     41GO:0005619; C:ascospore wall; ISS:RefGenome.::GO:0000324; C:fungal-type vacuole; TAS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006914; P:autophagy; IMP:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:PomBase.::GO:0051171; P:regulation of nitrogen compound metabolic process; IMP:PomBase.::GO:0006401; P:RNA catabolic process; IGI:PomBase.::GO:0007033; P:vacuole organization; IMP:PomBase.
93C5PCB1    397   SUB4A_COCP7 Subtilisin-like protease CPC735_0...2540.55     37.4     24     39GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
94C5NZ69    400   SUB7C_COCP7 Subtilisin-like protease CPC735_0...2570.59     37     26     40GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
95Q69F57    421   SUB2_TRIRU Subtilisin-like protease 2 OS=Tric...2570.68     37     25     40GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
96A9AES3    433   SYS_BURM1 Serine--tRNA ligase OS=Burkholderia...520.87     36.6     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
97Q9AEN2    433   SYS_BURCE Serine--tRNA ligase OS=Burkholderia...520.87     36.6     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
98C5P6D1    406   SUB2A_COCP7 Subtilisin-like protease CPC735_0...2630.97     36.6     26     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
99P59996    691   PCSK9_RAT Proprotein convertase subtilisin/ke...1181.4     36.2     29     44GO:0005615; C:extracellular space; ISS:HGNC.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0050750; F:low-density lipoprotein particle receptor binding; ISS:HGNC.::GO:0004252; F:serine-type endopeptidase activity; ISS:HGNC.
GO:0032869; P:cellular response to insulin stimulus; IDA:HGNC.::GO:0009267; P:cellular response to starvation; IDA:HGNC.::GO:0042632; P:cholesterol homeostasis; IEP:RGD.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:RGD.::GO:0001822; P:kidney development; IEP:HGNC.::GO:0001889; P:liver development; IEP:HGNC.::GO:0032802; P:low-density lipoprotein particle receptor catabolic process; ISS:HGNC.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0030182; P:neuron differentiation; ISS:HGNC.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:HGNC.::GO:0016540; P:protein autoprocessing; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
100Q63RS1    433   SYS_BURPS Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
101Q3JPQ8    433   SYS_BURP1 Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
102A3NY56    433   SYS_BURP0 Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
103A1V1N6    433   SYS_BURMS Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
104Q62HY1    433   SYS_BURMA Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
105A2S9G4    433   SYS_BURM9 Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
106A3MMN2    433   SYS_BURM7 Serine--tRNA ligase OS=Burkholderia...521.7     35.8     42     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
107B0SNL6    555   CYSI_LEPBP Sulfite reductase [NADPH] hemoprot...1281.9     35.8     23     42GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
108B0SF75    555   CYSI_LEPBA Sulfite reductase [NADPH] hemoprot...1281.9     35.8     23     42GO:0009337; C:sulfite reductase complex (NADPH); IEA:InterPro.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0004783; F:sulfite reductase (NADPH) activity; IEA:EC.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.
109G3FNQ9    426   SPAZ_ARTOL Cuticle-degrading serine protease ...601.9     35.4     32     52GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
110G1X8P8    409   SPAZ_ARTOA Cuticle-degrading serine protease ...602     35.4     32     52GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
111A3NCC8    433   SYS_BURP6 Serine--tRNA ligase OS=Burkholderia...522.4     35     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
112P81719    63   PIIS_ACHLY Protease 2 small chain OS=Achromob...672.5     32.7     33     48GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
113E4V2V9    400   SUB7_ARTGP Subtilisin-like protease 7 OS=gyps...922.6     35     27     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
114Q44633    456   MNME_BUCAP tRNA modification GTPase MnmE OS=B...1172.8     35     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
115P87184    495   ALP2_ASPFU Alkaline protease 2 OS=A1100) (Asp...2582.9     35     25     38
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0019863; F:IgE binding; IDA:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
116B0Y473    495   ALP2_ASPFC Alkaline protease 2 OS=(Aspergillu...2582.9     35     25     38
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
117C5P9H3    394   SUB7D_COCP7 Subtilisin-like protease CPC735_0...1432.9     35     29     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
118C5NZ70    407   SUB2C_COCP7 Subtilisin-like protease CPC735_0...2832.9     35     24     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
119Q0BHH5    433   SYS_BURCM Serine--tRNA ligase OS=cepacia (str...523     35     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
120A0K5F5    433   SYS_BURCH Serine--tRNA ligase OS=Burkholderia...523.1     34.7     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
121B1YUL5    433   SYS_BURA4 Serine--tRNA ligase OS=Burkholderia...523.3     34.7     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004828; F:serine-tRNA ligase activity; IEA:EC.
GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
records
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