rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q63415 | 937 | PCSK6_RAT Proprotein convertase subtilisin/ke... | 516 | 2e-100 | 338 | 38 | 54 | GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0016486; P:peptide hormone processing; IEP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 32 | P29122 | 969 | PCSK6_HUMAN Proprotein convertase subtilisin/... | 597 | 3e-100 | 338 | 35 | 52 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:BHF-UCL. | | | | | | | | | | GO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030510; P:regulation of BMP signaling pathway; TAS:BHF-UCL.::GO:0032940; P:secretion by cell; IDA:BHF-UCL. | 33 | P51559 | 943 | BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabdit... | 514 | 1e-99 | 337 | 37 | 55 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 34 | Q9NJ15 | 1696 | PCSK5_BRACL Proprotein convertase subtilisin/... | 492 | 8e-96 | 333 | 39 | 56 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 35 | Q92824 | 1860 | PCSK5_HUMAN Proprotein convertase subtilisin/... | 484 | 3e-95 | 332 | 40 | 57 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; ISS:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; ISS:BHF-UCL. | | | | | | | | | | GO:0042277; F:peptide binding; ISS:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0042089; P:cytokine biosynthetic process; ISS:BHF-UCL.::GO:0007566; P:embryo implantation; ISS:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; ISS:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; ISS:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002001; P:renin secretion into blood stream; IEP:BHF-UCL.::GO:0030323; P:respiratory tube development; ISS:BHF-UCL.::GO:0006465; P:signal peptide processing; IDA:HGNC.::GO:0019067; P:viral assembly, maturation, egress, and release; IEP:BHF-UCL. | 36 | P41413 | 1809 | PCSK5_RAT Proprotein convertase subtilisin/ke... | 484 | 4e-95 | 332 | 40 | 57 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 37 | Q04592 | 1877 | PCSK5_MOUSE Proprotein convertase subtilisin/... | 484 | 5e-95 | 332 | 40 | 57 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI. | | | | | | | | | | GO:0042277; F:peptide binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.::GO:0042089; P:cytokine biosynthetic process; IDA:BHF-UCL.::GO:0007566; P:embryo implantation; IMP:BHF-UCL.::GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.::GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.::GO:0007507; P:heart development; IMP:BHF-UCL.::GO:0001822; P:kidney development; IMP:BHF-UCL.::GO:0035108; P:limb morphogenesis; IMP:BHF-UCL.::GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.::GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030323; P:respiratory tube development; IMP:BHF-UCL.::GO:0019067; P:viral assembly, maturation, egress, and release; IDA:BHF-UCL. | 38 | P26016 | 1269 | FUR11_DROME Furin-like protease 1, isoforms 1... | 472 | 2e-93 | 324 | 39 | 60 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 39 | P30430 | 1101 | FUR1C_DROME Furin-like protease 1, isoform 1-... | 495 | 2e-93 | 322 | 38 | 59 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 40 | P23916 | 662 | PRCA_ANAVT Calcium-dependent protease OS=Anab... | 435 | 2e-36 | 149 | 32 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 41 | Q59149 | 662 | PRCA_NOSS1 Calcium-dependent protease OS=Nost... | 436 | 3e-35 | 146 | 32 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 42 | Q00139 | 370 | VG47_ICHVA Subtilisin-like protease OS=herpes... | 307 | 6e-16 | 84 | 25 | 43 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 43 | P42779 | 603 | BPRV_DICNO Extracellular basic protease OS=Di... | 522 | 0.000000000007 | 72.4 | 25 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 44 | P31339 | 621 | ASPA_AERSA Microbial serine proteinase OS=Aer... | 528 | 0.000000007 | 63.2 | 22 | 37 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 45 | P29141 | 806 | SUBV_BACSU Minor extracellular protease vpr O... | 194 | 0.0000001 | 59.3 | 32 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 46 | P42780 | 595 | BPRX_DICNO Extracellular subtilisin-like prot... | 315 | 0.0000001 | 58.9 | 26 | 38 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 47 | P29139 | 326 | ISP_PAEPO Intracellular serine protease OS=Pa... | 267 | 0.0000001 | 57.8 | 29 | 44 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 48 | O31788 | 442 | APRX_BACSU Serine protease AprX OS=Bacillus s... | 319 | 0.0000002 | 58.2 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 49 | P00782 | 382 | SUBT_BACAM Subtilisin BPN' OS=Bacillus amylol... | 274 | 0.0000002 | 57.8 | 30 | 44 | | | | | | | | | | | | | | | | | | | | | | 50 | P16396 | 645 | SUBE_BACSU Minor extracellular protease epr O... | 285 | 0.0000002 | 58.5 | 29 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 51 | P04189 | 381 | SUBT_BACSU Subtilisin E OS=Bacillus subtilis ... | 267 | 0.0000002 | 57.4 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 52 | P29143 | 530 | HLY_HAL17 Halolysin OS=Halophilic archaebacte... | 287 | 0.0000005 | 57 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 53 | P35835 | 381 | SUBN_BACNA Subtilisin NAT OS=Bacillus subtili... | 267 | 0.0000006 | 56.2 | 28 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.::GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 54 | P07518 | 275 | SUBT_BACPU Subtilisin OS=Bacillus pumilus (Ba... | 267 | 0.000005 | 52.8 | 27 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 55 | P23314 | 580 | EXPR_XANCP Extracellular protease OS=LMG 568)... | 335 | 0.000005 | 53.5 | 26 | 37 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 56 | P20724 | 378 | ELYA_BACYA Alkaline elastase YaB OS=Bacillus ... | 253 | 0.000006 | 53.1 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 57 | P11018 | 319 | ISP1_BACSU Major intracellular serine proteas... | 256 | 0.00002 | 51.6 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 58 | P29142 | 381 | SUBT_GEOSE Subtilisin J OS=Geobacillus stearo... | 273 | 0.00002 | 51.2 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 59 | P54423 | 894 | WPRA_BACSU Cell wall-associated protease OS=B... | 318 | 0.00002 | 51.6 | 28 | 39 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 60 | P00783 | 381 | SUBT_BACSA Subtilisin amylosacchariticus OS=B... | 273 | 0.00003 | 50.8 | 28 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 61 | Q45670 | 401 | THES_BACSJ Thermophilic serine proteinase OS=... | 233 | 0.00003 | 50.8 | 31 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |