UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL227C

Length:

590

Number of sequences:

5887

Description:

YNL227C JJJ1 SGDID:S000005171, Chr XIV from 222431-220659, Genome Release 64-1-1, reverse complement, Verified ORF, "Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P53863	590	JJJ1_YEAST J protein JJJ1 OS=Saccharomyces ce...	590	0	1204	100	100	GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005730; C:nucleolus; IMP:SGD.
									GO:0001671; F:ATPase activator activity; IDA:SGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IMP:SGD.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0042273; P:ribosomal large subunit biogenesis; IMP:SGD.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
2	Q5F1R6	531	DJC21_HUMAN DnaJ homolog subfamily C member 2...	598	1e-58	210	31	48	GO:0005840; C:ribosome; NAS:UniProtKB.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006457; P:protein folding; NAS:UniProtKB.
3	Q0II91	533	DJC21_BOVIN DnaJ homolog subfamily C member 2...	395	2e-56	204	35	53	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
4	Q6PGY5	545	DJC21_DANRE DnaJ homolog subfamily C member 2...	411	3e-55	201	33	53	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
5	O14213	380	MU185_SCHPO Meiotically up-regulated gene 185...	379	4e-27	117	28	45	GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0042254; P:ribosome biogenesis; ISS:PomBase.
6	Q6AYU3	357	DNJB6_RAT DnaJ homolog subfamily B member 6 O...	104	8e-18	89	44	63	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
7	Q74H58	373	DNAJ_GEOSL Chaperone protein DnaJ OS=Geobacte...	63	9e-18	89	68	83	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
8	O54946	365	DNJB6_MOUSE DnaJ homolog subfamily B member 6...	104	2e-17	87.8	44	63	GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IDA:MGI.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0060710; P:chorio-allantoic fusion; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
9	B1ZUS0	382	DNAJ_OPITP Chaperone protein DnaJ OS=Opitutus...	65	4e-17	87	66	78	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
10	Q8NHS0	232	DNJB8_HUMAN DnaJ homolog subfamily B member 8...	63	1e-16	84	62	81
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
11	Q4R7Y5	241	DNJB6_MACFA DnaJ homolog subfamily B member 6...	65	2e-16	83.6	60	78	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
12	Q9QYI7	227	DNJB8_MOUSE DnaJ homolog subfamily B member 8...	63	3e-16	82.4	62	81
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
13	Q5F3Z5	326	DNJB6_CHICK DnaJ homolog subfamily B member 6...	72	3e-16	83.2	58	76	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
14	Q9XCA6	383	DNAJ_PORGI Chaperone protein DnaJ OS=Porphyro...	63	4e-16	84.3	63	81	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
15	Q0III6	242	DNJB6_BOVIN DnaJ homolog subfamily B member 6...	65	4e-16	82.4	60	78	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
16	Q892R1	375	DNAJ_CLOTE Chaperone protein DnaJ OS=Clostrid...	85	6e-16	83.2	48	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
17	O75190	326	DNJB6_HUMAN DnaJ homolog subfamily B member 6...	65	0.000000000000001	82	60	78	GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
									GO:0001671; F:ATPase activator activity; IDA:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0031072; F:heat shock protein binding; IDA:UniProtKB.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0045109; P:intermediate filament organization; IDA:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
18	Q5R8H0	326	DNJB6_PONAB DnaJ homolog subfamily B member 6...	65	0.000000000000001	82	60	78	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
19	P25491	409	MAS5_YEAST Mitochondrial protein import prote...	71	0.000000000000001	83.2	56	73	GO:0005792; C:microsome; IDA:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:SGD.::GO:0072380; C:TRC complex; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0001671; F:ATPase activator activity; IDA:SGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IDA:SGD.
									GO:0006458; P:'de novo' protein folding; IMP:SGD.::GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0042026; P:protein refolding; IDA:SGD.::GO:0045047; P:protein targeting to ER; IMP:SGD.::GO:0006626; P:protein targeting to mitochondrion; IMP:SGD.::GO:0009408; P:response to heat; IEA:InterPro.
20	Q2S030	388	DNAJ_SALRD Chaperone protein DnaJ OS=Saliniba...	67	0.000000000000001	82.8	61	76	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
21	B2RLJ0	383	DNAJ_PORG3 Chaperone protein DnaJ OS=Porphyro...	63	0.000000000000002	82	62	81	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
22	Q9JMC3	397	DNJA4_MOUSE DnaJ homolog subfamily A member 4...	74	0.000000000000002	82	57	70	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
23	A3DF24	386	DNAJ_CLOTH Chaperone protein DnaJ OS=Clostrid...	63	0.000000000000002	81.6	65	75	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
24	Q5XGU5	245	DNJ6B_XENLA DnaJ homolog subfamily B member 6...	98	0.000000000000003	79.7	41	63	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
25	Q8WW22	397	DNJA4_HUMAN DnaJ homolog subfamily A member 4...	74	0.000000000000004	81.3	57	70	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
26	P25686	324	DNJB2_HUMAN DnaJ homolog subfamily B member 2...	151	0.000000000000004	80.1	39	50	GO:0016234; C:inclusion body; IDA:BHF-UCL.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0030544; F:Hsp70 protein binding; IPI:BHF-UCL.::GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.::GO:0070628; F:proteasome binding; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.
									GO:0030433; P:ER-associated protein catabolic process; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IGI:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IGI:UniProtKB.::GO:0090084; P:negative regulation of inclusion body assembly; IDA:BHF-UCL.::GO:0090086; P:negative regulation of protein deubiquitination; IDA:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006986; P:response to unfolded protein; TAS:ProtInc.
27	Q5FWN8	250	DNJ6A_XENLA DnaJ homolog subfamily B member 6...	72	0.000000000000005	79	51	76	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
28	Q1LJ82	379	DNAJ_RALME Chaperone protein DnaJ OS=Ralstoni...	65	0.000000000000005	80.5	58	83	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
29	Q0A7E4	383	DNAJ_ALHEH Chaperone protein DnaJ OS=Alkalili...	63	0.000000000000009	79.7	59	78	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
30	Q2VYT0	383	DNAJ_MAGSA Chaperone protein DnaJ OS=Magnetos...	63	0.00000000000001	79.7	62	76	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0009408; P:response to heat; IEA:InterPro.
31	Q862Z4	242	DNJB3_MACFU DnaJ homolog subfamily B member 3...	67	0.00000000000002	77.4	55	73
									GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.

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