UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL223W

Length:

494

Number of sequences:

5887

Description:

YNL223W ATG4 SGDID:S000005167, Chr XIV from 227370-228854, Genome Release 64-1-1, Verified ORF, "Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q9P373	320	ATG4_SCHPO Probable cysteine protease atg4 OS...	239	6e-40	151	33	53	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:PomBase.
									GO:0000045; P:autophagic vacuole assembly; ISS:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0032258; P:CVT pathway; ISS:PomBase.::GO:0016485; P:protein processing; ISS:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
32	Q6PZ02	393	ATG4B_CHICK Cysteine protease ATG4B OS=Gallus...	348	2e-34	137	28	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33	Q684M2	469	ATG4D_PIG Cysteine protease ATG4D OS=Sus scro...	325	4e-33	134	29	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
34	Q9Y4P1	393	ATG4B_HUMAN Cysteine protease ATG4B OS=Homo s...	346	2e-32	131	28	45	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0000045; P:autophagic vacuole assembly; IGI:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IDA:UniProtKB.
35	Q6DG88	394	ATG4B_DANRE Cysteine protease ATG4B OS=Danio ...	344	2e-31	129	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
36	Q86TL0	474	ATG4D_HUMAN Cysteine protease ATG4D OS=Homo s...	329	2e-31	129	28	44	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
37	Q8BGV9	474	ATG4D_MOUSE Cysteine protease ATG4D OS=Mus mu...	354	2e-31	129	27	43	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
									GO:0006914; P:autophagy; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
38	Q8BGE6	393	ATG4B_MOUSE Cysteine protease ATG4B OS=Mus mu...	349	4e-31	127	28	45	GO:0005737; C:cytoplasm; IDA:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
39	Q640G7	384	ATG4B_XENLA Cysteine protease ATG4B OS=Xenopu...	374	1e-30	125	28	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
40	Q6PZ03	393	ATG4B_BOVIN Cysteine protease ATG4B OS=Bos ta...	346	6e-30	124	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
41	Q6PZ05	398	ATG4A_BOVIN Cysteine protease ATG4A OS=Bos ta...	337	1e-29	123	27	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
42	Q8C9S8	396	ATG4A_MOUSE Cysteine protease ATG4A OS=Mus mu...	335	4e-29	121	28	43	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
									GO:0006914; P:autophagy; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
43	Q5XH30	450	ATG4C_XENLA Cysteine protease ATG4C OS=Xenopu...	426	1e-28	120	25	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
44	Q8WYN0	398	ATG4A_HUMAN Cysteine protease ATG4A OS=Homo s...	337	2e-28	119	27	43	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IDA:UniProtKB.
45	Q5R699	398	ATG4A_PONAB Cysteine protease ATG4A OS=Pongo ...	337	3e-28	119	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
46	Q96DT6	458	ATG4C_HUMAN Cysteine protease ATG4C OS=Homo s...	364	5e-28	119	26	40	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005576; C:extracellular region; IDA:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
									GO:0000045; P:autophagic vacuole assembly; IGI:UniProtKB.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.::GO:0006508; P:proteolysis; IDA:UniProtKB.
47	Q811C2	458	ATG4C_MOUSE Cysteine protease ATG4C OS=Mus mu...	409	8e-28	118	25	39	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
48	Q6GPU1	397	ATG4A_XENLA Cysteine protease ATG4A OS=Xenopu...	350	1e-27	117	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
49	Q68EP9	450	ATG4C_XENTR Cysteine protease ATG4C OS=Xenopu...	387	3e-27	117	26	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
50	Q5ZIW7	380	ATG4A_CHICK Cysteine protease ATG4A OS=Gallus...	352	3e-27	115	27	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
51	Q68FJ9	469	ATG4D_XENLA Cysteine protease ATG4D OS=Xenopu...	288	1e-24	109	29	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
52	Q9M1Y0	477	ATG4B_ARATH Cysteine protease ATG4b OS=Arabid...	267	2e-20	97.8	30	45
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
53	Q8S929	467	ATG4A_ARATH Cysteine protease ATG4a OS=Arabid...	266	4e-20	96.7	27	43
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54	Q75KP8	474	ATG4A_ORYSJ Cysteine protease ATG4A OS=Oryza ...	320	1e-18	92.4	28	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
55	Q2XPP4	478	ATG4B_ORYSI Cysteine protease ATG4B OS=Oryza ...	317	2e-18	91.7	27	41	GO:0005776; C:autophagic vacuole; ISS:Gramene.::GO:0005775; C:vacuolar lumen; ISS:Gramene.
									GO:0019786; F:APG8-specific protease activity; ISS:Gramene.::GO:0016807; F:cysteine-type carboxypeptidase activity; ISS:Gramene.
									GO:0006914; P:autophagy; ISS:Gramene.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
56	A2XHJ5	473	ATG4A_ORYSI Cysteine protease ATG4A OS=Oryza ...	364	4e-18	90.5	28	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
57	Q7XPW8	478	ATG4B_ORYSJ Cysteine protease ATG4B OS=Oryza ...	317	5e-18	90.5	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
58	A2Q1V6	487	ATG4_MEDTR Cysteine protease ATG4 OS=Medicago...	256	5e-17	87	28	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
59	Q557H7	745	ATG4_DICDI Cysteine protease atg4 OS=Dictyost...	128	0.00003	50.4	30	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; ISS:dictyBase.
									GO:0006914; P:autophagy; ISS:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; ISS:dictyBase.
60	Q9JL04	1578	FMN2_MOUSE Formin-2 OS=Mus musculus (Mouse). ...	107	2.6	34.7	29	42	GO:0015629; C:actin cytoskeleton; IEA:InterPro.
									GO:0003779; F:actin binding; IEA:InterPro.
									GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0051295; P:establishment of meiotic spindle localization; IMP:BHF-UCL.::GO:0016344; P:meiotic chromosome movement towards spindle pole; IMP:BHF-UCL.::GO:0007132; P:meiotic metaphase I; IMP:BHF-UCL.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IMP:BHF-UCL.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:BHF-UCL.
61	P32771	386	FADH_YEAST S-(hydroxymethyl)glutathione dehyd...	89	2.7	34.3	24	43	GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:SGD.::GO:0033833; F:hydroxymethylfurfural reductase (NADH) activity; IMP:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006069; P:ethanol oxidation; IEA:InterPro.::GO:0046294; P:formaldehyde catabolic process; IDA:SGD.::GO:0033859; P:furaldehyde metabolic process; IMP:SGD.

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