rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q8X505 | 248 | YDFG_ECO57 NADP-dependent L-serine/L-allo-thr... | 192 | 0.00002 | 48.5 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 392 | P51661 | 386 | DHI2_MOUSE Corticosteroid 11-beta-dehydrogena... | 161 | 0.00002 | 48.9 | 25 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 393 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 215 | 0.00003 | 48.5 | 21 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 394 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 207 | 0.00003 | 48.5 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 395 | Q8VCR2 | 304 | DHB13_MOUSE 17-beta-hydroxysteroid dehydrogen... | 187 | 0.00003 | 48.5 | 21 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 396 | Q02338 | 343 | BDH_HUMAN D-beta-hydroxybutyrate dehydrogenas... | 112 | 0.00003 | 48.1 | 23 | 53 | GO:0005759; C:mitochondrial matrix; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.::GO:0046952; P:ketone body catabolic process; TAS:Reactome. | 397 | B1LNJ7 | 270 | HCAB_ECOSM 3-phenylpropionate-dihydrodiol/cin... | 223 | 0.00003 | 48.1 | 25 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 398 | Q83QJ8 | 270 | HCAB_SHIFL 3-phenylpropionate-dihydrodiol/cin... | 220 | 0.00004 | 47.8 | 25 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 399 | Q0T1X8 | 270 | HCAB_SHIF8 3-phenylpropionate-dihydrodiol/cin... | 220 | 0.00004 | 47.8 | 25 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 400 | P50233 | 400 | DHI2_RAT Corticosteroid 11-beta-dehydrogenase... | 130 | 0.00005 | 47.8 | 28 | 45 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0007565; P:female pregnancy; IEP:RGD.::GO:0008211; P:glucocorticoid metabolic process; IDA:RGD.::GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.] | 401 | P28845 | 292 | DHI1_HUMAN Corticosteroid 11-beta-dehydrogena... | 213 | 0.00005 | 47.8 | 21 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.] | 402 | B5Z114 | 270 | HCAB_ECO5E 3-phenylpropionate-dihydrodiol/cin... | 223 | 0.00005 | 47.4 | 25 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 403 | Q8XA72 | 270 | HCAB_ECO57 3-phenylpropionate-dihydrodiol/cin... | 223 | 0.00005 | 47.4 | 25 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 404 | Q5E9H7 | 312 | DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1... | 220 | 0.00006 | 47.4 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 405 | Q6PUF3 | 287 | DHI1L_DANRE Hydroxysteroid 11-beta-dehydrogen... | 209 | 0.00006 | 47.4 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016229; F:steroid dehydrogenase activity; ISS:ZFIN. | | | | | | | | | | | 406 | Q3YZ12 | 270 | HCAB_SHISS 3-phenylpropionate-dihydrodiol/cin... | 223 | 0.00007 | 47 | 26 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 407 | P25970 | 253 | Y5909_MYXXD Uncharacterized oxidoreductase MX... | 166 | 0.00008 | 47 | 24 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 408 | Q99J47 | 323 | DRS7B_MOUSE Dehydrogenase/reductase SDR famil... | 189 | 0.00009 | 47 | 20 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 409 | O06544 | 250 | Y1144_MYCTU Uncharacterized oxidoreductase Rv... | 199 | 0.00009 | 46.6 | 26 | 44 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 410 | Q29608 | 291 | DHI1_SAISC Corticosteroid 11-beta-dehydrogena... | 206 | 0.00009 | 47 | 21 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 411 | Q3T0R4 | 325 | DRS7B_BOVIN Dehydrogenase/reductase SDR famil... | 206 | 0.0001 | 46.6 | 21 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 412 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 192 | 0.0001 | 46.6 | 25 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 413 | P44432 | 262 | FABI_HAEIN Enoyl-[acyl-carrier-protein] reduc... | 217 | 0.0001 | 46.6 | 27 | 43 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 414 | Q9ZMN7 | 275 | FABI_HELPJ Enoyl-[acyl-carrier-protein] reduc... | 204 | 0.0001 | 46.6 | 25 | 44 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 415 | P51658 | 381 | DHB2_MOUSE Estradiol 17-beta-dehydrogenase 2 ... | 168 | 0.0001 | 46.2 | 25 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | | 416 | Q5ZJG8 | 331 | HSDL1_CHICK Hydroxysteroid dehydrogenase-like... | 190 | 0.0002 | 46.2 | 24 | 44 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 417 | Q5XG41 | 318 | DH12A_XENLA Estradiol 17-beta-dehydrogenase 1... | 185 | 0.0002 | 45.8 | 23 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 418 | P37959 | 280 | YUSZ_BACSU Uncharacterized oxidoreductase yus... | 192 | 0.0002 | 45.4 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 419 | Q6Q7D2 | 287 | DHI1L_MACFA Hydroxysteroid 11-beta-dehydrogen... | 233 | 0.0003 | 45.4 | 22 | 39 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 420 | P40580 | 263 | BZRD_YEAST Benzil reductase ((S)-benzoin form... | 137 | 0.0003 | 45.1 | 26 | 48 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC. | | | | | | | | | | | 421 | P55435 | 248 | Y4EL_RHISN Uncharacterized short-chain type d... | 225 | 0.0003 | 44.7 | 24 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |