rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
301 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 260 | 0.00000006 | 56.2 | 25 | 44 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 302 | P29147 | 343 | BDH_RAT D-beta-hydroxybutyrate dehydrogenase,... | 169 | 0.00000007 | 56.6 | 24 | 47 | GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:RGD. | | | | | | | | | | GO:0060612; P:adipose tissue development; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 303 | Q5RA68 | 418 | HSDL2_PONAB Hydroxysteroid dehydrogenase-like... | 226 | 0.00000007 | 56.6 | 26 | 45 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 304 | P39644 | 259 | YWFH_BACSU Bacilysin biosynthesis oxidoreduct... | 90 | 0.00000007 | 55.8 | 31 | 54 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 305 | P15428 | 266 | PGDH_HUMAN 15-hydroxyprostaglandin dehydrogen... | 193 | 0.00000007 | 56.2 | 27 | 45 | GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; IDA:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IDA:UniProtKB.::GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB. | 306 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 209 | 0.00000008 | 55.8 | 27 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 307 | Q80XN0 | 343 | BDH_MOUSE D-beta-hydroxybutyrate dehydrogenas... | 190 | 0.00000009 | 56.2 | 24 | 44 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 308 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 226 | 0.0000001 | 56.2 | 26 | 45 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 309 | Q8MJY8 | 266 | PGDH_MACFA 15-hydroxyprostaglandin dehydrogen... | 193 | 0.0000001 | 55.5 | 27 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; IEP:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 310 | P39333 | 237 | YJGI_ECOLI Uncharacterized oxidoreductase yjg... | 174 | 0.0000001 | 55.1 | 21 | 44 | | | | | | | | | | | GO:0035438; F:cyclic-di-GMP binding; IDA:EcoCyc.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044010; P:single-species biofilm formation; IMP:EcoCyc. | 311 | Q0IH28 | 323 | DRS7B_XENLA Dehydrogenase/reductase SDR famil... | 207 | 0.0000001 | 55.8 | 21 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 312 | P71564 | 253 | Y945_MYCTU Uncharacterized oxidoreductase Rv0... | 231 | 0.0000001 | 55.1 | 23 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 313 | Q2FZQ3 | 256 | FABI_STAA8 Enoyl-[acyl-carrier-protein] reduc... | 230 | 0.0000002 | 55.1 | 28 | 44 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IDA:UniProtKB.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0050661; F:NADP binding; IDA:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 314 | Q566S6 | 309 | DRS7B_DANRE Dehydrogenase/reductase SDR famil... | 214 | 0.0000002 | 55.5 | 20 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 315 | P14061 | 328 | DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 ... | 132 | 0.0000002 | 55.5 | 27 | 51 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 316 | Q0VFE7 | 309 | DRS7B_XENTR Dehydrogenase/reductase SDR famil... | 203 | 0.0000002 | 55.1 | 22 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 317 | P0AEK6 | 262 | FABI_SHIFL Enoyl-[acyl-carrier-protein] reduc... | 155 | 0.0000002 | 54.7 | 30 | 47 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.::GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.] | 318 | P0AEK4 | 262 | FABI_ECOLI Enoyl-[acyl-carrier-protein] reduc... | 155 | 0.0000002 | 54.7 | 30 | 47 | GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; IMP:UniProtKB.::GO:0030497; P:fatty acid elongation; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.] | 319 | P0AEK5 | 262 | FABI_ECO57 Enoyl-[acyl-carrier-protein] reduc... | 155 | 0.0000002 | 54.7 | 30 | 47 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.::GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.] | 320 | O34782 | 263 | YVRD_BACSU Uncharacterized oxidoreductase yvr... | 261 | 0.0000002 | 54.7 | 21 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 321 | Q1WNP0 | 328 | DHB1_PANTR Estradiol 17-beta-dehydrogenase 1 ... | 132 | 0.0000002 | 55.1 | 27 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro. | 322 | P16657 | 262 | FABI_SALTY Enoyl-[acyl-carrier-protein] reduc... | 155 | 0.0000002 | 54.7 | 30 | 47 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.::GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.] | 323 | Q8CQD2 | 257 | BUTA_STAES Diacetyl reductase [(S)-acetoin fo... | 259 | 0.0000002 | 54.7 | 23 | 40 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 324 | Q9NKW1 | 441 | MFEA_DICDI Peroxisomal multifunctional enzyme... | 191 | 0.0000002 | 55.1 | 27 | 42 | GO:0005777; C:peroxisome; TAS:dictyBase. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 325 | P40747 | 689 | YUXG_BACSU Uncharacterized oxidoreductase yux... | 199 | 0.0000003 | 55.1 | 26 | 42 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 326 | Q5HKG6 | 257 | BUTA_STAEQ Diacetyl reductase [(S)-acetoin fo... | 199 | 0.0000003 | 53.9 | 23 | 42 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 327 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 193 | 0.0000003 | 54.3 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 328 | P80365 | 405 | DHI2_HUMAN Corticosteroid 11-beta-dehydrogena... | 130 | 0.0000004 | 54.7 | 30 | 49 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc. | 329 | Q4V8F9 | 524 | HSDL2_RAT Hydroxysteroid dehydrogenase-like p... | 141 | 0.0000004 | 54.7 | 29 | 50 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 330 | Q3ZBV9 | 255 | DHR11_BOVIN Dehydrogenase/reductase SDR famil... | 243 | 0.0000004 | 53.5 | 26 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 331 | P42556 | 289 | PTR1_LEITA Pteridine reductase 1 OS=Leishmani... | 90 | 0.0000005 | 53.9 | 33 | 57 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047040; F:pteridine reductase activity; IEA:EC. | | | | | | | | | | GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW. |