Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL189W
Length:
542
Number of sequences:
5887
Description:
YNL189W SRP1 SGDID:S000005133, Chr XIV from 284260-285888, Genome Release 64-1-1, Verified ORF, "Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q19969    514   IMA3_CAEEL Importin subunit alpha-3 OS=Caenor...5212e-133     405     43     62GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005643; C:nuclear pore; IMP:UniProtKB.
GO:0005515; F:protein binding; IPI:WormBase.::GO:0008565; F:protein transporter activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007128; P:meiotic prophase I; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006999; P:nuclear pore organization; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006606; P:protein import into nucleus; IMP:UniProtKB.::GO:0016246; P:RNA interference; IMP:WormBase.
32A9QM74    516   IMA8_HUMAN Importin subunit alpha-8 OS=Homo s...5056e-124     380     42     60GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006606; P:protein import into nucleus; IEA:InterPro.
33C6K7I2    507   IMA8_PIG Importin subunit alpha-8 OS=Sus scro...5101e-121     374     41     60GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
34P52295    522   IMA_DROME Importin subunit alpha OS=Drosophil...5173e-121     374     42     60GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0007301; P:female germline ring canal formation; IMP:FlyBase.::GO:0042332; P:gravitaxis; IMP:FlyBase.::GO:0048542; P:lymph gland development; IMP:FlyBase.::GO:0006606; P:protein import into nucleus; IEA:InterPro.::GO:0007291; P:sperm individualization; IMP:FlyBase.
35C1JZ66    522   IMA8_BOVIN Importin subunit alpha-8 OS=Bos ta...5045e-118     365     41     59GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
36Q557F4    550   IMA1A_DICDI Probable importin subunit alpha-A...5488e-117     363     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
37C0LLJ0    499   IMA8_MOUSE Importin subunit alpha-8 OS=Mus mu...5093e-109     342     39     57GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
38P91276    531   IMA2_CAEEL Importin subunit alpha-2 OS=Caenor...5286e-91     295     35     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005643; C:nuclear pore; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:WormBase.::GO:0008565; F:protein transporter activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007084; P:mitotic nuclear envelope reassembly; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006606; P:protein import into nucleus; IMP:UniProtKB.::GO:0051983; P:regulation of chromosome segregation; IMP:WormBase.
39Q9FYP9    528   IMA2_ORYSJ Importin subunit alpha-2 OS=Oryza ...5219e-52     190     27     47GO:0005634; C:nucleus; IEA:InterPro.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
40A8MYJ9    163   IMA2L_HUMAN Importin subunit alpha-2-like pro...800.002     42.7     36     50GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
41Q22560    524   IMA1_CAEEL Importin subunit alpha-1 OS=Caenor...5352e-18     92.4     21     43GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005643; C:nuclear pore; IMP:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:WormBase.::GO:0008565; F:protein transporter activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006606; P:protein import into nucleus; IMP:UniProtKB.
42Q6FJV1    582   VAC8_CANGA Vacuolar protein 8 OS=NRRL Y-65) (...2510.015     41.6     24     46GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
43Q6CX49    579   VAC8_KLULA Vacuolar protein 8 OS=1267 / NRRL ...4400.0000000000006     75.1     25     45GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
44P39968    578   VAC8_YEAST Vacuolar protein 8 OS=Saccharomyce...3120.003     43.9     22     45GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0071563; C:Myo2p-Vac17p-Vac8p transport complex; IDA:SGD.::GO:0071561; C:nucleus-vacuole junction; IDA:SGD.
GO:0043495; F:protein anchor; IMP:SGD.
GO:0071255; P:CVT vesicle assembly; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0071562; P:nucleus-vacuole junction assembly; IMP:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
45Q9JLI7    507   SPAG6_MOUSE Sperm-associated antigen 6 OS=Mus...1198.9     32.7     27     44GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI.
46Q4I1B1    539   VAC8_GIBZE Vacuolar protein 8 OS=(Wheat head ...2650.004     43.5     24     43GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
47Q2U5T5    578   VAC8_ASPOR Vacuolar protein 8 OS=Aspergillus ...2010.88     36.2     26     38GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
48O43028    550   VAC8_SCHPO Vacuolar protein 8 OS=Schizosaccha...4190.00000002     60.5     24     42GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0043495; F:protein anchor; ISS:PomBase.
GO:0071255; P:CVT vesicle assembly; ISS:PomBase.::GO:0016236; P:macroautophagy; ISS:PomBase.::GO:0042144; P:vacuole fusion, non-autophagic; ISS:PomBase.::GO:0000011; P:vacuole inheritance; ISS:PomBase.
49B7U179    737   ABAP1_ARATH ARMADILLO BTB ARABIDOPSIS PROTEIN...3900.00000003     60.1     23     43GO:0031261; C:DNA replication preinitiation complex; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006261; P:DNA-dependent DNA replication; TAS:TAIR.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:2000104; P:negative regulation of DNA-dependent DNA replication; IMP:UniProtKB.
50P0CM60    630   VAC8_CRYNJ Vacuolar protein 8 OS=ATCC MYA-565...3170.34     37.4     22     38GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
51P0CM61    630   VAC8_CRYNB Vacuolar protein 8 OS=(Filobasidie...3170.34     37.4     22     38GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
52O75602    509   SPAG6_HUMAN Sperm-associated antigen 6 OS=Hom...1192.7     34.3     27     44GO:0005930; C:axoneme; TAS:ProtInc.::GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0019861; C:flagellum; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; TAS:ProtInc.
53Q4WVW4    578   VAC8_ASPFU Vacuolar protein 8 OS=A1100) (Aspe...2170.91     36.2     24     40GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
54Q2GW27    560   VAC8_CHAGB Vacuolar protein 8 OS=6347 / NRRL ...1620.083     39.3     28     44GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
55Q6BTZ4    560   VAC8_DEBHA Vacuolar protein 8 OS=0083 / IGC 2...2450.076     39.3     24     44GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
56Q59MN0    585   VAC8_CANAL Vacuolar protein 8 OS=Candida albi...3750.000006     52.8     24     43GO:0000324; C:fungal-type vacuole; ISS:CGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
GO:0030448; P:hyphal growth; IMP:CGD.::GO:0000011; P:vacuole inheritance; IMP:CGD.
57Q7RXW1    578   VAC8_NEUCR Vacuolar protein 8 OS=1257 / FGSC ...1179.5     32.7     25     45GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
58B9DHT4    710   ARIA_ARATH ARM REPEAT PROTEIN INTERACTING WIT...2100.0004     46.6     20     45GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0010187; P:negative regulation of seed germination; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
59Q757R0    568   VAC8_ASHGO Vacuolar protein 8 OS=Y-1056) (Yea...2550.002     44.3     25     47GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
60A2RT91    1465   ANKAR_MOUSE Ankyrin and armadillo repeat-cont...3075.5     33.5     19     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
61Q14669    1992   TRIPC_HUMAN Probable E3 ubiquitin-protein lig...2910.000008     52.8     23     43GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
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