Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL189W
Length:
542
Number of sequences:
5887
Description:
YNL189W SRP1 SGDID:S000005133, Chr XIV from 284260-285888, Genome Release 64-1-1, Verified ORF, "Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q02821    542   IMA1_YEAST Importin subunit alpha OS=Saccharo...5420     1117     100     100GO:0005634; C:nucleus; IDA:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IDA:SGD.
GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.
2O94374    539   IMA2_SCHPO Importin subunit alpha-2 OS=Schizo...5320     611     58     74GO:0005829; C:cytosol; IDA:PomBase.::GO:0005643; C:nuclear pore; TAS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0040023; P:establishment of nucleus localization; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
3O14063    542   IMA1_SCHPO Importin subunit alpha-1 OS=Schizo...5280     607     57     76GO:0005737; C:cytoplasm; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005525; F:GTP binding; NAS:PomBase.::GO:0030674; F:protein binding, bridging; IPI:PomBase.::GO:0008565; F:protein transporter activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IGI:PomBase.::GO:0030261; P:chromosome condensation; IMP:PomBase.::GO:0000087; P:M phase of mitotic cell cycle; IMP:PomBase.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
4Q9SLX0    534   IMA1B_ORYSJ Importin subunit alpha-1b OS=Oryz...5402e-178     521     54     68GO:0005634; C:nucleus; IEA:InterPro.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
5Q96321    532   IMA1_ARATH Importin subunit alpha-1 OS=Arabid...5396e-177     517     55     67GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005635; C:nuclear envelope; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
6Q5RBV0    536   IMA7_PONAB Importin subunit alpha-7 OS=Pongo ...5116e-177     517     54     72GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
7O60684    536   IMA7_HUMAN Importin subunit alpha-7 OS=Homo s...5116e-177     517     54     72GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.
GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.
8O35345    536   IMA7_MOUSE Importin subunit alpha-7 OS=Mus mu...5117e-177     517     54     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006606; P:protein import into nucleus; IDA:MGI.
9Q0V7M0    536   IMA7_BOVIN Importin subunit alpha-7 OS=Bos ta...5119e-177     516     54     72GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.
10Q71VM4    526   IMA1A_ORYSJ Importin subunit alpha-1a OS=Oryz...5311e-172     506     53     68GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006606; P:protein import into nucleus; IEA:InterPro.
11O15131    536   IMA5_HUMAN Importin subunit alpha-6 OS=Homo s...5158e-171     501     53     71GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.
12O22478    527   IMA_SOLLC Importin subunit alpha OS=Solanum l...5053e-169     497     55     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
13Q503E9    536   IMA5_DANRE Importin subunit alpha-6 OS=Danio ...5226e-169     496     52     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
14Q56R16    536   IMA5_RAT Importin subunit alpha-6 OS=Rattus n...5184e-167     492     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
15Q5ZML1    538   IMA1_CHICK Importin subunit alpha-1 OS=Gallus...5194e-166     489     52     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
16P83953    538   IMA1_RAT Importin subunit alpha-1 OS=Rattus n...5191e-164     486     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
17Q76P29    516   IMAB_DICDI Importin subunit alpha-B OS=Dictyo...5302e-164     484     49     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
18P52294    538   IMA1_HUMAN Importin subunit alpha-1 OS=Homo s...5153e-164     484     51     70GO:0005829; C:cytosol; TAS:Reactome.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000018; P:regulation of DNA recombination; TAS:ProtInc.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome.
19A2VE08    538   IMA1_BOVIN Importin subunit alpha-1 OS=Bos ta...5193e-164     484     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
20Q5R909    538   IMA1_PONAB Importin subunit alpha-1 OS=Pongo ...5194e-164     484     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
21O04294    531   IMA2_ARATH Importin subunit alpha-2 OS=Arabid...5321e-163     483     52     67GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006952; P:defense response; IMP:TAIR.::GO:0006606; P:protein import into nucleus; IEA:InterPro.
22Q60960    538   IMA1_MOUSE Importin subunit alpha-1 OS=Mus mu...5192e-163     483     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
23O00629    521   IMA4_HUMAN Importin subunit alpha-4 OS=Homo s...5222e-150     448     47     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005488; F:binding; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.
24O35343    521   IMA4_MOUSE Importin subunit alpha-4 OS=Mus mu...5223e-150     448     47     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
GO:0006606; P:protein import into nucleus; IDA:MGI.
25P52293    529   IMA2_MOUSE Importin subunit alpha-2 OS=Mus mu...5243e-149     446     45     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008565; F:protein transporter activity; IEA:InterPro.
26O35344    521   IMA3_MOUSE Importin subunit alpha-3 OS=Mus mu...5313e-148     443     47     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
27P52292    529   IMA2_HUMAN Importin subunit alpha-2 OS=Homo s...5351e-147     442     45     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0008139; F:nuclear localization sequence binding; IDA:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006259; P:DNA metabolic process; TAS:ProtInc.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000072; P:M phase specific microtubule process; TAS:ProtInc.::GO:0006607; P:NLS-bearing substrate import into nucleus; IDA:UniProtKB.::GO:0000018; P:regulation of DNA recombination; TAS:ProtInc.
28O00505    521   IMA3_HUMAN Importin subunit alpha-3 OS=Homo s...5312e-146     438     47     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0006461; P:protein complex assembly; TAS:ProtInc.
29P52170    522   IMA1_XENLA Importin subunit alpha-1 OS=Xenopu...5284e-138     417     44     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
30P52171    523   IMA2_XENLA Importin subunit alpha-2 OS=Xenopu...5172e-137     415     44     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0006606; P:protein import into nucleus; IEA:InterPro.
31Q19969    514   IMA3_CAEEL Importin subunit alpha-3 OS=Caenor...5212e-133     405     43     62GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005643; C:nuclear pore; IMP:UniProtKB.
GO:0005515; F:protein binding; IPI:WormBase.::GO:0008565; F:protein transporter activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007128; P:meiotic prophase I; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006999; P:nuclear pore organization; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0006606; P:protein import into nucleus; IMP:UniProtKB.::GO:0016246; P:RNA interference; IMP:WormBase.
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