Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL186W
Length:
792
Number of sequences:
5887
Description:
YNL186W UBP10 SGDID:S000005130, Chr XIV from 289498-291876, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P35123    962   UBP4_MOUSE Ubiquitin carboxyl-terminal hydrol...1950.00000009     59.7     25     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
92Q5UQR3    468   UBPL1_MIMIV Probable ubiquitin carboxyl-termi...4500.000000000002     73.6     23     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
93B4HUI5    1059   UBP36_DROSE Ubiquitin carboxyl-terminal hydro...1460.00000001     62.8     28     46GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
94Q5RCD3    963   UBP4_PONAB Ubiquitin carboxyl-terminal hydrol...1950.00000008     59.7     26     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
95P32571    926   UBP4_YEAST Ubiquitin carboxyl-terminal hydrol...4040.000000000003     74.3     25     38GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000502; C:proteasome complex; IPI:SGD.
GO:0004175; F:endopeptidase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:SGD.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0010995; P:free ubiquitin chain depolymerization; IDA:SGD.::GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006275; P:regulation of DNA replication; IMP:SGD.::GO:0010992; P:ubiquitin homeostasis; IMP:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
96Q9SCJ9    1067   UBP26_ARATH Ubiquitin carboxyl-terminal hydro...3640.000000000003     74.3     24     41GO:0005730; C:nucleolus; IDA:TAIR.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0048316; P:seed development; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
97Q9P7V9    585   UBP9_SCHPO Probable ubiquitin carboxyl-termin...3660.000000000003     73.6     22     38GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
98Q9FPS9    924   UBP15_ARATH Ubiquitin carboxyl-terminal hydro...1830.000000002     65.5     27     46GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:TAIR.::GO:0009908; P:flower development; IMP:TAIR.::GO:0010154; P:fruit development; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0016579; P:protein deubiquitination; IDA:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
99A6ZY34    926   UBP4_YEAS7 Ubiquitin carboxyl-terminal hydrol...4040.000000000004     73.9     25     38GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
100Q9FIQ1    732   UBP21_ARATH Ubiquitin carboxyl-terminal hydro...1700.006     43.9     24     43
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
101B3LGK1    926   UBP4_YEAS1 Ubiquitin carboxyl-terminal hydrol...4040.000000000004     73.6     25     38GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
102A5WWB0    370   UBP46_DANRE Ubiquitin carboxyl-terminal hydro...3710.000000000005     72     23     40
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007610; P:behavior; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
103P0C7H9    530   U17L7_HUMAN Inactive ubiquitin carboxyl-termi...3830.000000000007     72.4     21     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
104A3AF13    1079   UBP26_ORYSJ Ubiquitin carboxyl-terminal hydro...1920.000001     55.8     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
105A2XDG4    1079   UBP26_ORYSI Ubiquitin carboxyl-terminal hydro...1920.000001     55.8     27     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
106Q4WQI1    775   CREB_ASPFU Probable ubiquitin carboxyl-termin...2650.000000000009     72.4     25     38
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
107A6QR55    963   UBP4_BOVIN Ubiquitin carboxyl-terminal hydrol...2040.00000004     60.8     25     42GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
108Q13107    963   UBP4_HUMAN Ubiquitin carboxyl-terminal hydrol...1950.00000007     60.1     26     42GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
109B0Y4P5    767   CREB_ASPFC Probable ubiquitin carboxyl-termin...2650.00000000001     72.4     25     38
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
110Q0CT11    768   CREB_ASPTN Probable ubiquitin carboxyl-termin...3160.00000000001     72.4     25     40
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
111A1CW53    761   CREB_NEOFI Probable ubiquitin carboxyl-termin...3440.00000000001     72     23     36
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
112Q3KR59    794   UBP10_RAT Ubiquitin carboxyl-terminal hydrola...4560.00000000001     72     23     38GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
113A1A5G2    1354   UBP47_XENTR Ubiquitin carboxyl-terminal hydro...4520.00000000001     72.4     19     36GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
114Q8BY87    1376   UBP47_MOUSE Ubiquitin carboxyl-terminal hydro...4220.00000000001     72     19     37GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0034644; P:cellular response to UV; IMP:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
115Q6FQF0    887   UBP4_CANGA Ubiquitin carboxyl-terminal hydrol...4320.00000000002     71.6     22     35GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
116B8NSV5    755   CREB_ASPFN Probable ubiquitin carboxyl-termin...2070.00000000002     71.6     29     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
117Q3UJD6    1360   UBP19_MOUSE Ubiquitin carboxyl-terminal hydro...1990.002     45.4     21     40GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IMP:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
118Q2UUG8    754   CREB_ASPOR Probable ubiquitin carboxyl-termin...2070.00000000002     71.6     29     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
119Q6J1Y9    1357   UBP19_RAT Ubiquitin carboxyl-terminal hydrola...1990.003     45.1     21     40GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IMP:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; IEP:UniProtKB.
120A7TGY3    882   UBP4_VANPO Ubiquitin carboxyl-terminal hydrol...4380.00000000002     71.2     24     34GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
121O94966    1318   UBP19_HUMAN Ubiquitin carboxyl-terminal hydro...1990.005     44.3     21     40GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
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