Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL186W
Length:
792
Number of sequences:
5887
Description:
YNL186W UBP10 SGDID:S000005130, Chr XIV from 289498-291876, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q949Y0    482   UBP6_ARATH Ubiquitin carboxyl-terminal hydrol...480.00002     52     46     65GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005516; F:calmodulin binding; IDA:TAIR.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IGI:TAIR.
GO:0016579; P:protein deubiquitination; TAS:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
212B1AY13    2617   UBP24_MOUSE Ubiquitin carboxyl-terminal hydro...1820.068     40.8     23     41
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
213P50101    1230   UBP15_YEAST Ubiquitin carboxyl-terminal hydro...4110.00003     51.2     23     36GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; IC:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
214O60139    593   UBP4_SCHPO Probable ubiquitin carboxyl-termin...4060.00003     51.2     22     38GO:0032153; C:cell division site; IDA:PomBase.::GO:0005768; C:endosome; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
215F1N5V1    981   UBP37_BOVIN Ubiquitin carboxyl-terminal hydro...770.005     44.3     36     53
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
216Q9VYQ8    1129   UBP7_DROME Ubiquitin carboxyl-terminal hydrol...1640.005     44.3     25     45GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:FlyBase.::GO:0043234; C:protein complex; IPI:FlyBase.::GO:0035328; C:transcriptionally silent chromatin; IDA:FlyBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006342; P:chromatin silencing; IGI:FlyBase.::GO:0016578; P:histone deubiquitination; IDA:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
217Q86T82    979   UBP37_HUMAN Ubiquitin carboxyl-terminal hydro...770.007     43.9     36     53GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
218F1SRY5    982   UBP37_PIG Ubiquitin carboxyl-terminal hydrola...770.005     44.3     36     53
GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0035871; P:protein K11-linked deubiquitination; ISS:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
219O00507    2555   USP9Y_HUMAN Probable ubiquitin carboxyl-termi...1360.0001     49.7     28     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
220P70398    2559   USP9X_MOUSE Probable ubiquitin carboxyl-termi...1360.0001     49.7     26     41GO:0045177; C:apical part of cell; IDA:MGI.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
221Q9USM5    849   UBP1_SCHPO Probable ubiquitin carboxyl-termin...1920.01     43.1     23     38GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
222Q93008    2570   USP9X_HUMAN Probable ubiquitin carboxyl-termi...1360.0001     49.7     27     43GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007292; P:female gamete generation; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
223P25037    809   UBP1_YEAST Ubiquitin carboxyl-terminal hydrol...600.0002     48.5     38     57GO:0005783; C:endoplasmic reticulum; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
224Q9P2H5    1018   UBP35_HUMAN Ubiquitin carboxyl-terminal hydro...1750.0004     47.8     23     40
GO:0005488; F:binding; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
225Q9HBJ7    922   UBP29_HUMAN Ubiquitin carboxyl-terminal hydro...470.45     37.7     47     64
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
GO:0006464; P:protein modification process; NAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
226Q6A4J8    1103   UBP7_MOUSE Ubiquitin carboxyl-terminal hydrol...1710.21     38.9     23     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
227Q93009    1102   UBP7_HUMAN Ubiquitin carboxyl-terminal hydrol...1710.22     38.9     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
228Q4VSI4    1103   UBP7_RAT Ubiquitin carboxyl-terminal hydrolas...1710.22     38.9     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:RGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
229Q6U7I1    1101   UBP7_CHICK Ubiquitin carboxyl-terminal hydrol...1710.34     38.1     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
230Q8NFA0    1604   UBP32_HUMAN Ubiquitin carboxyl-terminal hydro...573.4     35     32     47GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; TAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
231Q09879    1108   UBP5_SCHPO Probable ubiquitin carboxyl-termin...1000.025     42     31     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
232F1QFS9    860   UBP13_DANRE Ubiquitin carboxyl-terminal hydro...640.002     45.4     36     55
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
233Q9UTT1    1129   UBP21_SCHPO Ubiquitin carboxyl-terminal hydro...1750.24     38.9     27     41GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; IMP:PomBase.::GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0045859; P:regulation of protein kinase activity; IGI:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
234P45974    858   UBP5_HUMAN Ubiquitin carboxyl-terminal hydrol...410.004     44.7     41     61GO:0005764; C:lysosome; TAS:ProtInc.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
235P35125    1406   UBP6_HUMAN Ubiquitin carboxyl-terminal hydrol...570.95     37     35     49GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:UniProtKB.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0060627; P:regulation of vesicle-mediated transport; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
236Q5R407    858   UBP5_PONAB Ubiquitin carboxyl-terminal hydrol...410.004     44.7     41     61
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
237P56399    858   UBP5_MOUSE Ubiquitin carboxyl-terminal hydrol...410.004     44.7     41     61
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
238A4QNN3    519   UBP30_XENTR Ubiquitin carboxyl-terminal hydro...3250.005     43.9     20     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
239Q5I043    1051   UBP28_MOUSE Ubiquitin carboxyl-terminal hydro...750.006     43.9     39     57GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; ISS:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
240Q84WU2    1115   UBP13_ARATH Ubiquitin carboxyl-terminal hydro...1091.4     36.2     29     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
241Q96RU2    1077   UBP28_HUMAN Ubiquitin carboxyl-terminal hydro...750.008     43.5     36     56GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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