Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL186W
Length:
792
Number of sequences:
5887
Description:
YNL186W UBP10 SGDID:S000005130, Chr XIV from 289498-291876, Genome Release 64-1-1, Verified ORF, "Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121O94966    1318   UBP19_HUMAN Ubiquitin carboxyl-terminal hydro...1990.005     44.3     21     40GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
122O57429    357   UBP2_CHICK Ubiquitin carboxyl-terminal hydrol...1890.0002     48.1     25     43GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:Roslin.
GO:0016579; P:protein deubiquitination; IDA:Roslin.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
123A2Q9N1    758   CREB_ASPNC Probable ubiquitin carboxyl-termin...2110.00000000003     70.9     28     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
124A1CIL1    760   CREB_ASPCL Probable ubiquitin carboxyl-termin...2070.00000000004     70.5     28     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0045013; P:carbon catabolite repression of transcription; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
125Q5U252    1350   UBP47_XENLA Ubiquitin carboxyl-terminal hydro...4520.00000000005     70.5     19     36GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006284; P:base-excision repair; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
126Q9FPS7    695   UBP20_ARATH Ubiquitin carboxyl-terminal hydro...1660.002     45.1     22     40
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
127Q5RE63    375   UBP18_PONAB Ubl carboxyl-terminal hydrolase 1...1650.00000000005     68.9     27     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
128Q9FPT5    1083   UBP1_ARATH Ubiquitin carboxyl-terminal hydrol...1340.000003     54.7     31     50
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
129Q9UMW8    372   UBP18_HUMAN Ubl carboxyl-terminal hydrolase 1...1670.0000000001     67.8     27     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:LIFEdb.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
130Q8R5H1    981   UBP15_MOUSE Ubiquitin carboxyl-terminal hydro...1280.00000005     60.5     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
131Q9Y4E8    981   UBP15_HUMAN Ubiquitin carboxyl-terminal hydro...1280.00000006     60.1     31     50
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
132O75604    605   UBP2_HUMAN Ubiquitin carboxyl-terminal hydrol...1820.0002     48.5     25     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
133Q5U349    618   UBP2_RAT Ubiquitin carboxyl-terminal hydrolas...1870.00009     49.7     25     41GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
134O88623    613   UBP2_MOUSE Ubiquitin carboxyl-terminal hydrol...1870.0001     49.3     25     41GO:0005938; C:cell cortex; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
135Q2NL57    791   UB10A_XENLA Ubiquitin carboxyl-terminal hydro...4470.0000000002     68.2     22     35GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
136Q9UK80    565   UBP21_HUMAN Ubiquitin carboxyl-terminal hydro...2070.002     45.4     24     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
137Q70CQ4    1352   UBP31_HUMAN Ubiquitin carboxyl-terminal hydro...1940.042     41.2     21     37
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
138Q6P8X6    390   UBP50_MOUSE Putative ubiquitin carboxyl-termi...1750.0007     46.6     25     41
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
139Q99K46    921   UBP11_MOUSE Ubiquitin carboxyl-terminal hydro...1910.000007     53.5     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
140Q2KJ72    565   UBP21_BOVIN Ubiquitin carboxyl-terminal hydro...2070.013     42.7     24     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
141Q8K387    813   UBP45_MOUSE Ubiquitin carboxyl-terminal hydro...2060.0000000003     67.4     28     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
142Q7ZXR7    805   UB10B_XENLA Ubiquitin carboxyl-terminal hydro...4470.0000000003     67.4     22     35GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
143P39944    805   UBP5_YEAST Ubiquitin carboxyl-terminal hydrol...1650.0000000004     67     30     43GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
144Q24574    1556   UBPE_DROME Ubiquitin carboxyl-terminal hydrol...830.04     41.2     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0031935; P:regulation of chromatin silencing; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
145Q9WTV6    368   UBP18_MOUSE Ubl carboxyl-terminal hydrolase 1...1680.0000000005     65.9     26     49
GO:0019785; F:ISG15-specific protease activity; IMP:MGI.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0032020; P:ISG15-protein conjugation; IMP:MGI.::GO:0035634; P:response to stilbenoid; IEP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
146Q6DIJ4    805   UBP10_XENTR Ubiquitin carboxyl-terminal hydro...4470.0000000006     66.6     22     34GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0042980; F:cystic fibrosis transmembrane conductance regulator binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
147P39538    1254   UBP12_YEAST Ubiquitin carboxyl-terminal hydro...1550.00000004     60.8     28     48GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
148Q9QZL6    566   UBP21_MOUSE Ubiquitin carboxyl-terminal hydro...2080.031     41.6     24     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
149Q754R5    848   UBP4_ASHGO Ubiquitin carboxyl-terminal hydrol...1800.0000000009     66.2     29     46GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
150Q96K76    1375   UBP47_HUMAN Ubiquitin carboxyl-terminal hydro...4220.0000000009     66.2     19     37GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0071987; F:WD40-repeat domain binding; IPI:UniProtKB.
GO:0006284; P:base-excision repair; IMP:UniProtKB.::GO:0034644; P:cellular response to UV; ISS:UniProtKB.::GO:0035520; P:monoubiquitinated protein deubiquitination; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
151B2GUX4    565   UBP21_RAT Ubiquitin carboxyl-terminal hydrola...2070.01     42.7     24     35GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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