Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL183C
Length:
790
Number of sequences:
5887
Description:
YNL183C NPR1 SGDID:S000005127, Chr XIV from 295509-293137, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571O74304    1436   WIN1_SCHPO MAP kinase kinase kinase win1 OS=S...2430.000000000000006     83.2     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:PomBase.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0031098; P:stress-activated protein kinase signaling cascade; IGI:PomBase.
572Q8SQW2    329   CTK1_ENCCU Probable CTD kinase subunit alpha ...1940.000000000000006     80.5     35     49GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
573Q8JH47    464   CDK8_DANRE Cyclin-dependent kinase 8 OS=Danio...2130.000000000000006     81.6     27     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
574O55098    966   STK10_MOUSE Serine/threonine-protein kinase 1...2000.000000000000006     82.8     29     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
575P0C431    357   HOG1_GIBZE Mitogen-activated protein kinase H...2050.000000000000006     80.5     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
576Q6CR51    593   SSN3_KLULA Serine/threonine-protein kinase SS...1830.000000000000006     82.4     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
577Q9R0A5    511   NEK3_MOUSE Serine/threonine-protein kinase Ne...2190.000000000000006     82     30     46GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
578Q8NJT7    359   HOG1_HORWE Mitogen-activated protein kinase H...2210.000000000000006     80.5     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
579Q56R42    365   HOG1_CRYNV Mitogen-activated protein kinase H...2210.000000000000007     80.5     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
580P0CP68    365   HOG1_CRYNJ Mitogen-activated protein kinase H...2210.000000000000007     80.5     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
581P0CP69    365   HOG1_CRYNB Mitogen-activated protein kinase H...2210.000000000000007     80.5     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
582P23573    314   CDC2C_DROME Cell division control protein 2 c...2010.000000000000007     79.7     30     48GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:FlyBase.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:FlyBase.::GO:0007259; P:JAK-STAT cascade; IPI:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
583Q14AX6    1484   CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus...2120.000000000000007     82.8     27     45GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:HGNC.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
584P13185    1064   KIN1_YEAST Serine/threonine protein kinase KI...2260.000000000000007     82.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
585Q2PQN9    292   CDK5_GLOMM Cyclin-dependent kinase 5 homolog ...1910.000000000000007     79.7     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.
586Q8SRU0    319   CSK2A_ENCCU Probable casein kinase II subunit...1610.000000000000008     79.7     34     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
587P08092    470   RAN1_SCHPO Negative regulator of sexual conju...2270.000000000000008     81.3     29     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0000746; P:conjugation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0031138; P:negative regulation of conjugation with cellular fusion; TAS:PomBase.::GO:0045835; P:negative regulation of meiosis; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
588Q9NB31    497   CST1_CAEEL Serine/threonine-protein kinase cs...2010.000000000000008     81.6     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0048747; P:muscle fiber development; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
589D2H526    1491   CDK12_AILME Cyclin-dependent kinase 12 OS=Ail...2120.000000000000008     82.8     27     45GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
590Q63844    380   MK03_MOUSE Mitogen-activated protein kinase 3...2130.000000000000008     80.5     31     49GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031143; C:pseudopodium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:MGI.::GO:0001784; F:phosphotyrosine binding; IMP:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051216; P:cartilage development; IDA:MGI.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:2000657; P:negative regulation of apolipoprotein binding; IMP:BHF-UCL.::GO:0009887; P:organ morphogenesis; IDA:MGI.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB.
591B5DE93    1239   CDK12_XENTR Cyclin-dependent kinase 12 OS=Xen...3370.000000000000008     82.4     22     41GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
592Q17446    377   PMK1_CAEEL Mitogen-activated protein kinase p...3100.000000000000009     80.5     25     44GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:WormBase.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0012501; P:programmed cell death; IMP:WormBase.
593P0C661    612   CDK8_CAEBR Cyclin-dependent kinase 8 OS=Caeno...2160.000000000000009     82     26     48GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
594P28829    659   BYR2_SCHPO Protein kinase byr2 OS=Schizosacch...2150.000000000000009     82     29     50GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
595Q80Y86    549   MK15_MOUSE Mitogen-activated protein kinase 1...3240.000000000000009     81.6     25     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
596P21708    380   MK03_RAT Mitogen-activated protein kinase 3 O...2130.000000000000009     80.5     31     49GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019369; P:arachidonic acid metabolic process; IEP:RGD.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000189; P:MAPK import into nucleus; IDA:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:RGD.
597Q3U3Q1    472   ULK3_MOUSE Serine/threonine-protein kinase UL...2070.000000000000009     81.3     31     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
598Q90327    427   MK08A_CYPCA Mitogen-activated protein kinase ...2400.000000000000009     80.9     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
599Q13555    558   KCC2G_HUMAN Calcium/calmodulin-dependent prot...3120.000000000000009     81.6     24     40GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030073; P:insulin secretion; NAS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
600Q96TL5    358   HOG1_NEUCR Mitogen-activated protein kinase h...2050.000000000000009     80.1     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
601Q5REX1    925   SIK2_PONAB Serine/threonine-protein kinase SI...2330.000000000000009     82     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
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