Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL183C
Length:
790
Number of sequences:
5887
Description:
YNL183C NPR1 SGDID:S000005127, Chr XIV from 295509-293137, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation; phosphorylates Aly2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q9DG02    475   KCC2D_XENLA Calcium/calmodulin-dependent prot...3120.000000000000001     84.3     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
452Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...2500.000000000000001     84.7     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
453A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...2140.000000000000001     84.3     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
454Q12706    436   PSK1_SCHPO Serine/threonine-protein kinase ps...1940.000000000000001     84     27     53GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IC:PomBase.
455Q6P3N6    464   CDK8_XENTR Cyclin-dependent kinase 8 OS=Xenop...2130.000000000000001     84     27     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
456O14098    593   CTK1_SCHPO CTD kinase subunit alpha OS=Schizo...2400.000000000000001     84.7     28     44GO:0005730; C:nucleolus; IDA:PomBase.::GO:0008024; C:positive transcription elongation factor complex b; NAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0031566; P:contractile ring maintenance involved in cell cycle cytokinesis; IMP:PomBase.::GO:0031565; P:cytokinesis checkpoint; IMP:PomBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; IGI:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
457Q8C0N0    497   SMKZ_MOUSE Sperm motility kinase Z OS=Mus mus...2130.000000000000001     84.3     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
458Q5N942    360   SAPK4_ORYSJ Serine/threonine-protein kinase S...2070.000000000000001     82.8     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
459Q9NQU5    681   PAK6_HUMAN Serine/threonine-protein kinase PA...2500.000000000000001     84.7     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.
460Q6PHZ2    499   KCC2D_MOUSE Calcium/calmodulin-dependent prot...3120.000000000000001     84.3     25     40GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0030315; C:T-tubule; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0060048; P:cardiac muscle contraction; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
461Q13557    499   KCC2D_HUMAN Calcium/calmodulin-dependent prot...3120.000000000000001     84.3     25     40GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
462Q6AX33    1482   MAST3_XENLA Microtubule-associated serine/thr...2080.000000000000001     85.5     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
463Q9SJG9    606   MPK20_ARATH Mitogen-activated protein kinase ...2150.000000000000001     84.7     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
464Q5Z6X0    514   CIPKP_ORYSJ CBL-interacting protein kinase 25...1640.000000000000001     84.3     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
465E2QWQ2    527   NLK_CANFA Serine/threonine-protein kinase NLK...2050.000000000000001     84.3     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
466O60307    1309   MAST3_HUMAN Microtubule-associated serine/thr...2080.000000000000001     85.1     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
467D3ZSZ3    527   NLK_RAT Serine/threonine-protein kinase NLK O...2050.000000000000001     84.3     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
468O54949    527   NLK_MOUSE Serine/threonine-protein kinase NLK...2050.000000000000001     84.3     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
469Q8SSV3    652   MKCD_DICDI Probable serine/threonine-protein ...1930.000000000000001     84.7     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
470P87253    1142   KPC1_NEUCR Protein kinase C-like OS=1257 / FG...2580.000000000000001     85.1     27     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
471Q9UBE8    527   NLK_HUMAN Serine/threonine-protein kinase NLK...2050.000000000000001     84.3     28     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
472Q0D0P5    364   HOG1_ASPTN Mitogen-activated protein kinase h...2210.000000000000001     82.8     34     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
473P15791    533   KCC2D_RAT Calcium/calmodulin-dependent protei...3120.000000000000001     84     25     40GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
474Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...2000.000000000000001     84.7     32     47GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
475Q9W739    302   CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana ...1990.000000000000001     81.6     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
476Q69ZA1    1511   CDK13_MOUSE Cyclin-dependent kinase 13 OS=Mus...2120.000000000000001     85.1     28     46GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.
477A2QRF6    365   HOG1_ASPNC Mitogen-activated protein kinase h...2990.000000000000001     82.4     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
478D3ZHP7    472   ULK3_RAT Serine/threonine-protein kinase ULK3...2090.000000000000002     83.6     31     54GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
479Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...3100.000000000000002     84.3     24     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
480Q03114    292   CDK5_RAT Cyclin-dependent kinase 5 OS=Rattus ...1910.000000000000002     81.6     29     47GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; TAS:RGD.::GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IDA:RGD.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:RGD.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:RGD.::GO:0006913; P:nucleocytoplasmic transport; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0045055; P:regulated secretory pathway; IMP:RGD.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0009611; P:response to wounding; IMP:RGD.::GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; IMP:RGD.
481O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...2060.000000000000002     83.6     31     50GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
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