Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL180C
Length:
331
Number of sequences:
5887
Description:
YNL180C RHO5 SGDID:S000005124, Chr XIV from 300649-299654, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
721B3LPD8    417   YPT11_YEAS1 GTP-binding protein YPT11 OS=Sacc...870.00006     48.1     30     51GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
722Q7TNZ5    183   REBL1_RAT GTPase RhebL1 OS=Rattus norvegicus ...1830.00006     46.6     27     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
723Q86L51    205   RAPB_DICDI Ras-related protein rapB OS=Dictyo...1720.00006     47     26     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
724Q15382    184   RHEB_HUMAN GTP-binding protein Rheb OS=Homo s...1660.00006     46.6     28     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032008; P:positive regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
725Q5RD87    189   RASN_PONAB GTPase NRas OS=Pongo abelii (Sumat...2030.00006     46.6     25     41GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
726P01120    322   RAS2_YEAST Ras-like protein 2 OS=Saccharomyce...1480.00006     47.8     23     43GO:0005886; C:plasma membrane; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007190; P:activation of adenylate cyclase activity; TAS:SGD.::GO:0030437; P:ascospore formation; IMP:SGD.::GO:0000411; P:positive regulation of transcription by galactose; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; TAS:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
727P08644    189   RASK_RAT GTPase KRas OS=Rattus norvegicus (Ra...2000.00007     46.6     23     38GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0019002; F:GMP binding; IDA:RGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030275; F:LRR domain binding; IDA:RGD.
GO:0019221; P:cytokine-mediated signaling pathway; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:RGD.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0051385; P:response to mineralocorticoid stimulus; IEP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
728P32883    189   RASK_MOUSE GTPase KRas OS=Mus musculus (Mouse...2000.00007     46.6     23     38GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IGI:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; IGI:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IGI:MGI.::GO:0032228; P:regulation of synaptic transmission, GABAergic; IGI:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI.::GO:0008542; P:visual learning; IGI:MGI.
729Q969Q5    203   RAB24_HUMAN Ras-related protein Rab-24 OS=Hom...2000.00007     46.6     25     40GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
730Q62639    184   RHEB_RAT GTP-binding protein Rheb OS=Rattus n...1660.00007     46.2     28     42GO:0030425; C:dendrite; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.
GO:0032008; P:positive regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; NAS:RGD.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD.
731Q921J2    184   RHEB_MOUSE GTP-binding protein Rheb OS=Mus mu...1670.00007     46.2     28     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IDA:MGI.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0032008; P:positive regulation of TOR signaling cascade; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
732P79737    188   RASN_DANRE GTPase NRas OS=Danio rerio (Zebraf...2000.00007     46.6     24     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
733P22280    205   RAS3_MUCCL Ras-like protein 3 OS=lusitanicus)...2000.00007     46.6     23     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
734Q56JV3    184   RHEB_BOVIN GTP-binding protein Rheb OS=Bos ta...1660.00007     46.2     28     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0032008; P:positive regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
735Q4PB75    752   GEM1_USTMA Mitochondrial Rho GTPase 1 OS=Usti...2330.00008     48.1     26     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
736Q20365    307   RAB33_CAEEL Ras-related protein Rab-33 OS=Cae...1600.00008     47.4     25     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
737Q5EFX7    188   RASK_KRYMA GTPase KRas OS=Kryptolebias marmor...2000.00009     46.2     23     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
738Q7Z444    233   RASE_HUMAN GTPase ERas OS=Homo sapiens (Human...1560.00009     47     25     39GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
739B4KB60    181   RAS1_DROMO Ras-like protein 1 OS=Drosophila m...2000.00009     46.2     24     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
740Q2HJF8    631   MIRO1_BOVIN Mitochondrial Rho GTPase 1 OS=Bos...2230.0001     47.8     23     41GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
741P35290    203   RAB24_MOUSE Ras-related protein Rab-24 OS=Mus...2000.0001     46.2     26     40GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
742Q96D21    266   RHES_HUMAN GTP-binding protein Rhes OS=Homo s...2120.0001     47     23     40GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031681; F:G-protein beta-subunit binding; IPI:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IC:UniProtKB.
743Q8BG51    631   MIRO1_MOUSE Mitochondrial Rho GTPase 1 OS=Mus...2230.0001     47.8     23     41GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
744Q86YS6    212   RAB43_HUMAN Ras-related protein Rab-43 OS=Hom...2300.0001     46.2     23     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
745Q8IXI2    618   MIRO1_HUMAN Mitochondrial Rho GTPase 1 OS=Hom...2230.0001     47.4     23     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0019725; P:cellular homeostasis; IMP:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
746O42277    188   RASK_ORYLA GTPase KRas OS=Oryzias latipes (Me...2000.0001     45.8     23     39GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
747P36862    203   YPTV3_VOLCA GTP-binding protein yptV3 OS=Volv...2100.0001     46.2     23     39GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
748P63033    266   RHES_RAT GTP-binding protein Rhes OS=Rattus n...2120.0001     46.6     23     40GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
749P63032    266   RHES_MOUSE GTP-binding protein Rhes OS=Mus mu...2120.0001     46.6     23     40GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007626; P:locomotory behavior; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:UniProtKB.
750Q5F470    207   RAB8A_CHICK Ras-related protein Rab-8A OS=Gal...1300.0001     46.2     22     42GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
751Q8VEL9    341   REM2_MOUSE GTP-binding protein REM 2 OS=Mus m...1420.0001     47     31     42GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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