Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL180C
Length:
331
Number of sequences:
5887
Description:
YNL180C RHO5 SGDID:S000005124, Chr XIV from 300649-299654, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
661P08642    189   RASH_CHICK GTPase HRas OS=Gallus gallus (Chic...2000.00001     48.9     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
662P24409    200   RAB10_CANFA Ras-related protein Rab-10 OS=Can...1650.00001     48.9     22     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
663Q8CB87    725   RAB44_MOUSE Ras-related protein Rab-44 OS=Mus...1960.00001     50.4     24     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
664P20171    189   RASH_RAT GTPase HRas OS=Rattus norvegicus (Ra...2000.00001     48.5     23     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:RGD.::GO:0007265; P:Ras protein signal transduction; IMP:RGD.::GO:0035176; P:social behavior; IEP:RGD.
665Q61411    189   RASH_MOUSE GTPase HRas OS=Mus musculus (Mouse...2000.00001     48.5     23     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0008283; P:cell proliferation; IPI:MGI.::GO:0006897; P:endocytosis; IDA:MGI.::GO:0008629; P:induction of apoptosis by intracellular signals; IMP:MGI.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
666P01112    189   RASH_HUMAN GTPase HRas OS=Homo sapiens (Human...2000.00001     48.5     23     39GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0090398; P:cellular senescence; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
667Q95ME4    189   RASN_MONDO GTPase NRas OS=Monodelphis domesti...2020.00001     48.5     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
668Q5ZIT5    200   RAB10_CHICK Ras-related protein Rab-10 OS=Gal...1650.00002     48.5     23     41GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
669Q54RX9    214   RAB5B_DICDI Putative ras-related protein Rab-...1370.00002     48.9     24     47
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
670Q8R367    199   RERG_MOUSE Ras-related and estrogen-regulated...2170.00002     48.5     24     40GO:0016020; C:membrane; IEA:InterPro.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
671Q8TAI7    183   REBL1_HUMAN GTPase RhebL1 OS=Homo sapiens (Hu...1830.00002     48.1     27     40GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB.
672Q96AX2    223   RAB37_HUMAN Ras-related protein Rab-37 OS=Hom...1570.00002     48.9     22     41GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
673P12825    189   RASN_CAVPO GTPase NRas OS=Cavia porcellus (Gu...2020.00002     48.1     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
674P08556    189   RASN_MOUSE GTPase NRas OS=Mus musculus (Mouse...2020.00002     48.1     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
675Q9XI98    206   RAG3E_ARATH Ras-related protein RABG3e OS=Ara...2080.00002     48.5     23     38GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
676Q5R615    229   RB33B_PONAB Ras-related protein Rab-33B OS=Po...1610.00002     48.9     28     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
677Q504M8    260   RAB26_MOUSE Ras-related protein Rab-26 OS=Mus...2090.00002     48.9     22     42GO:0031226; C:intrinsic to plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0035272; P:exocrine system development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
678P90726    202   RAB18_CAEBR Ras-related protein Rab-18 OS=Cae...2220.00002     48.5     22     40GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
679Q2MJK3    189   RASN_PIG GTPase NRas OS=Sus scrofa (Pig). GN=...2020.00002     48.1     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
680P01111    189   RASN_HUMAN GTPase NRas OS=Homo sapiens (Human...2020.00002     48.1     24     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
681O35963    229   RB33B_MOUSE Ras-related protein Rab-33B OS=Mu...1610.00002     48.5     28     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
682Q9H082    229   RB33B_HUMAN Ras-related protein Rab-33B OS=Ho...1610.00002     48.5     28     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
683P20791    203   RAB8B_DICDI Ras-related protein Rab-8B OS=Dic...1300.00002     48.1     23     44GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:dictyBase.
GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031157; P:regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
684Q04970    189   RASN_RAT GTPase NRas OS=Rattus norvegicus (Ra...2020.00002     48.1     23     38GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
685Q8IXI1    618   MIRO2_HUMAN Mitochondrial Rho GTPase 2 OS=Hom...2240.00002     49.7     26     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0019725; P:cellular homeostasis; IMP:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
686Q8BU31    183   RAP2C_MOUSE Ras-related protein Rap-2c OS=Mus...2280.00002     47.8     27     43GO:0005829; C:cytosol; IDA:MGI.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0031954; P:positive regulation of protein autophosphorylation; IDA:MGI.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; IDA:UniProtKB.
687Q9Y3L5    183   RAP2C_HUMAN Ras-related protein Rap-2c OS=Hom...2280.00002     47.8     27     43GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
688Q08DI5    183   RAP2C_BOVIN Ras-related protein Rap-2c OS=Bos...2280.00002     47.8     27     43GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
689P79800    188   RASK_MELGA GTPase KRas OS=Meleagris gallopavo...2000.00002     47.8     23     38GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
690Q5R4A3    207   RAB8A_PONAB Ras-related protein Rab-8A OS=Pon...1710.00002     48.1     20     42GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
691Q8MXS1    203   RAB18_CAEEL Ras-related protein Rab-18 OS=Cae...2220.00002     48.1     22     40GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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