Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YNL172W
Length:
1748
Number of sequences:
5887
Description:
YNL172W APC1 SGDID:S000005116, Chr XIV from 310636-315882, Genome Release 64-1-1, Verified ORF, "Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53886    1748   APC1_YEAST Anaphase-promoting complex subunit...17480     3593     100     100GO:0005680; C:anaphase-promoting complex; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0010458; P:exit from mitosis; IMP:SGD.::GO:0007091; P:mitotic metaphase/anaphase transition; IMP:SGD.::GO:0016567; P:protein ubiquitination; IMP:SGD.
2P24686    2067   BIME_EMENI Negative regulator of mitosis OS=1...1655e-18     94.7     33     55GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
3Q9URV2    1458   APC1_SCHPO Anaphase-promoting complex subunit...1850.006     45.4     28     42GO:0005680; C:anaphase-promoting complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase.
4Q9H1A4    1944   APC1_HUMAN Anaphase-promoting complex subunit...1650.00002     53.9     30     52GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
5P53995    1944   APC1_MOUSE Anaphase-promoting complex subunit...1650.000009     54.7     30     53GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
6Q9FFF9    1678   APC1_ARATH Anaphase-promoting complex subunit...1460.00000002     63.2     32     52GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
7Q54NC6    2269   APC1_DICDI Anaphase-promoting complex subunit...2080.000005     55.5     25     44GO:0005680; C:anaphase-promoting complex; ISS:dictyBase.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:dictyBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:dictyBase.
8P20436    146   RPAB3_YEAST DNA-directed RNA polymerases I, I...683.3     34.7     26     46GO:0005736; C:DNA-directed RNA polymerase I complex; IDA:SGD.::GO:0005665; C:DNA-directed RNA polymerase II, core complex; IDA:SGD.::GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD.
GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006360; P:transcription from RNA polymerase I promoter; IPI:SGD.::GO:0006366; P:transcription from RNA polymerase II promoter; IPI:SGD.::GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IDA:SGD.
9Q5M900    488   B3GL2_XENTR UDP-GalNAc:beta-1,3-N-acetylgalac...883.9     35.8     27     40GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
GO:0006486; P:protein glycosylation; IEA:InterPro.
10Q12428    516   PRPD_YEAST Probable 2-methylcitrate dehydrata...1616.2     35     26     44GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0047547; F:2-methylcitrate dehydratase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
records
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